The Dichotomous Pattern of IL-12R and IL-23R Expression Elucidates the Role of IL-12 and IL-23 in Inflammation

Cutting Edge: NKT Cells Constitutively Express IL-23 Receptor and ROR t and Rapidly Produce IL-17 upon Receptor Ligation in an IL-6-Independent Fashion

(2014) A. V. Rachitskaya et al.   JOURNAL OF IMMUNOLOGY

Developmental Expression of IL-12R 2 on Murine Naive Neonatal T Cells Counters the Upregulation of IL-13R 1 on Primary Th1 Cells and Balances Immunity in the Newborn

(2013) C. M. Hoeman et al.   JOURNAL OF IMMUNOLOGY

Dynamic regulatory network controlling TH17 cell differentiation

(2013) Nir Yosef et al.   NATURE

Interleukin-18, more than a Th1 cytokine

(2013) Daniela Novick et al.   SEMINARS IN IMMUNOLOGY

Th22 Cells Are an Important Source of IL-22 for Host Protection against Enteropathogenic Bacteria

(2012) Rajatava Basu et al.   IMMUNITY

Innate Lymphoid Cells Promote Anatomical Containment of Lymphoid-Resident Commensal Bacteria

(2012) G. F. Sonnenberg et al.   SCIENCE

Genetic polymorphisms of IL-23R and IL-17A and novel insights into their associations with inflammatory bowel disease

(2011) S. W. Kim et al.   GUT

Interleukin-27 and interleukin-23 modulate human plasmacell functions

(2011) C. Cocco et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Association of IL-12B Genetic Polymorphism with the Susceptibility and Disease Severity of Ankylosing Spondylitis

(2011) R.-H. WONG et al.   JOURNAL OF RHEUMATOLOGY

Opposing consequences of IL-23 signaling mediated by innate and adaptive cells in chemically induced colitis in mice

(2011) J H Cox et al.   Mucosal Immunology

Therapeutic targeting of the IL-12/23 pathways: generation and characterization of ustekinumab

(2011) Jacqueline M Benson et al.   NATURE BIOTECHNOLOGY

Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis

(2011) George F Mells et al.   NATURE GENETICS

Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

(2011) Manuel A Rivas et al.   NATURE GENETICS

Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages

(2011) Wei Liao et al.   NATURE IMMUNOLOGY

Inflammatory disease protective R381Q IL23 receptor polymorphism results in decreased primary CD4+ and CD8+ human T-cell functional responses

(2011) R. Sarin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-23 Receptor Regulates Unconventional IL-17–Producing T Cells That Control Bacterial Infections

(2010) Lorena Riol-Blanco et al.   JOURNAL OF IMMUNOLOGY

Resequencing of positional candidates identifies low frequency IL23R coding variants protecting against inflammatory bowel disease

(2010) Yukihide Momozawa et al.   NATURE GENETICS

IL-12 initiates tumor rejection via lymphoid tissue–inducer cells bearing the natural cytotoxicity receptor NKp46

(2010) Maya Eisenring et al.   NATURE IMMUNOLOGY

The Natural Cytotoxicity Receptor NKp46 Is Dispensable for IL-22-Mediated Innate Intestinal Immune Defense against Citrobacter rodentium

(2009) N. Satoh-Takayama et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: IL-23 Receptor GFP Reporter Mice Reveal Distinct Populations of IL-17-Producing Cells

(2009) Amit Awasthi et al.   JOURNAL OF IMMUNOLOGY

CD27 is a thymic determinant of the balance between interferon-γ- and interleukin 17–producing γδ T cell subsets

(2009) Julie C Ribot et al.   NATURE IMMUNOLOGY

Primary Biliary Cirrhosis Associated withHLA, IL12A,andIL12RB2Variants

(2009) Gideon M. Hirschfield et al.   NEW ENGLAND JOURNAL OF MEDICINE

Investigation of association of the IL12B and IL23R genes with psoriatic arthritis

(2008) Charlotte Filer et al.   ARTHRITIS AND RHEUMATISM

Th memory for interleukin-17 expression is stablein vivo

(2008) Maria H. Lexberg et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Lymphoid tissue inducer–like cells are an innate source of IL-17 and IL-22

(2008) Hiroaki Takatori et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

(2008) Jeffrey C Barrett et al.   NATURE GENETICS

A Genome-Wide Association Study of Psoriasis and Psoriatic Arthritis Identifies New Disease Loci

(2008) Ying Liu et al.   PLoS Genetics