Regulators of Human White Adipose Browning: Evidence for Sympathetic Control and Sexual Dimorphic Responses to Sprint Interval Training

Irisin and exercise training in humans – Results from a randomized controlled training trial

(2013) Anne Hecksteden et al.   BMC Medicine

The effects of acute and chronic exercise on PGC-1α, irisin and browning of subcutaneous adipose tissue in humans

(2013) Frode Norheim et al.   FEBS Journal

Irisin Is Expressed and Produced by Human Muscle and Adipose Tissue in Association With Obesity and Insulin Resistance

(2013) José María Moreno-Navarrete et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Are skeletal muscleFNDC5gene expression and irisin release regulated by exercise and related to health?

(2013) Satu Pekkala et al.   JOURNAL OF PHYSIOLOGY-LONDON

Exercise training does not increase muscle FNDC5 protein or mRNA expression in pigs

(2013) John N. Fain et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

FNDC5/Irisin Is Not Only a Myokine but Also an Adipokine

(2013) Arturo Roca-Rivada et al.   PLoS One

Acute Exercise Induces FGF21 Expression in Mice and in Healthy Humans

(2013) Kook Hwan Kim et al.   PLoS One

Modulating fibroblast growth factor 21 in hyperphagic OLETF rats with daily exercise and caloric restriction

(2012) Justin A. Fletcher et al.   Applied Physiology Nutrition and Metabolism

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

(2012) Jun Wu et al.   CELL

FGF21 regulates PGC-1  and browning of white adipose tissues in adaptive thermogenesis

(2012) f. M. Fisher et al.   GENES & DEVELOPMENT

Fibroblast growth factor-21 serum concentrations are associated with metabolic and hepatic markers in humans

(2012) Susan Kralisch et al.   JOURNAL OF ENDOCRINOLOGY

Sympathetic inhibition attenuates hypoxia induced insulin resistance in healthy adult humans

(2012) Garrett L. Peltonen et al.   JOURNAL OF PHYSIOLOGY-LONDON

FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise

(2012) Joo Young Huh et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

(2012) Pontus Boström et al.   NATURE

Circulating levels of irisin in patients with anorexia nervosa and different stages of obesity – Correlation with body mass index

(2012) Andreas Stengel et al.   PEPTIDES

Exercise Increases Serum Fibroblast Growth Factor 21 (FGF21) Levels

(2012) Daniel Cuevas-Ramos et al.   PLoS One

Cold but not sympathomimetics activates human brown adipose tissue in vivo

(2012) A. M. Cypess et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sprint interval running increases insulin sensitivity in young healthy subjects

(2012) Marit Sandvei et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Implications of nonshivering thermogenesis for energy balance regulation in humans

(2011) Wouter D. van Marken Lichtenbelt et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Thermogenic Activation Induces FGF21 Expression and Release in Brown Adipose Tissue

(2011) Elayne Hondares et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

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(2011) Dionysios Chartoumpekis et al.   MOLECULAR MEDICINE

Autonomic recovery following sprint interval exercise

(2011) M. I. Stuckey et al.   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

Short-term sympathoadrenal inhibition augments the thermogenic response to β-adrenergic receptor stimulation

(2010) Sean A Newsom et al.   JOURNAL OF ENDOCRINOLOGY

Short-term sprint interval training increases insulin sensitivity in healthy adults but does not affect the thermogenic response to β-adrenergic stimulation

(2010) Jennifer C. Richards et al.   JOURNAL OF PHYSIOLOGY-LONDON

Run Sprint Interval Training Improves Aerobic Performance but Not Maximal Cardiac Output

(2010) REBECCA E. K. MACPHERSON et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models—association with liver and adipose tissue effects

(2009) Jing Xu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Brown Fat in Humans: Turning up the Heat on Obesity

(2009) P. Seale et al.   DIABETES

Functional Brown Adipose Tissue in Healthy Adults

(2009) Kirsi A. Virtanen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cold-Activated Brown Adipose Tissue in Healthy Men

(2009) Wouter D. van Marken Lichtenbelt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Serum FGF21 Levels Are Increased in Obesity and Are Independently Associated With the Metabolic Syndrome in Humans

(2008) X. Zhang et al.   DIABETES

Increased serum pigment epithelium derived factor levels in Type 2 diabetes patients

(2008) Alicia Jenkins et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Isoform-Specific Increases in Murine Skeletal Muscle Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α (PGC-1α) mRNA in Response to β2-Adrenergic Receptor Activation and Exercise

(2008) Shinji Miura et al.   ENDOCRINOLOGY

The Klotho gene family as a regulator of endocrine fibroblast growth factors

(2008) Hiroshi Kurosu et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Adipose Fibroblast Growth Factor 21 Is Up-Regulated by Peroxisome Proliferator-Activated Receptor   and Altered Metabolic States

(2008) E. S. Muise et al.   MOLECULAR PHARMACOLOGY

Similar metabolic adaptations during exercise after low volume sprint interval and traditional endurance training in humans

(2007) Kirsten A. Burgomaster et al.   JOURNAL OF PHYSIOLOGY-LONDON