Selective Inhibition of PI3K/Akt/mTOR Signaling Pathway Regulates Autophagy of Macrophage and Vulnerability of Atherosclerotic Plaque

Everolimus Causing Severe Hypertriglyceridemia and Acute Pancreatitis

(2017) Somasundaram Subramaniam et al.   Journal of the National Comprehensive Cancer Network

Complement C2 siRNA mediated therapy of myasthenia gravis in mice

(2013) Ruksana Huda et al.   JOURNAL OF AUTOIMMUNITY

Molecular Biology of Atherosclerosis

(2013) Paul N. Hopkins   PHYSIOLOGICAL REVIEWS

MAPK15/ERK8 stimulates autophagy by interacting with LC3 and GABARAP proteins

(2012) David Colecchia et al.   Autophagy

Autophagy Links Inflammasomes to Atherosclerotic Progression

(2012) Babak Razani et al.   Cell Metabolism

Beclin 1 Is Required for Starvation-Enhanced, but Not Rapamycin-Enhanced, LC3-Associated Phagocytosis of Burkholderia pseudomallei in RAW 264.7 Cells

(2012) Xuelei Li et al.   INFECTION AND IMMUNITY

β-catenin confers resistance to PI3K and AKT inhibitors and subverts FOXO3a to promote metastasis in colon cancer

(2012) Stephan P Tenbaum et al.   NATURE MEDICINE

IKBKE Protein Activates Akt Independent of Phosphatidylinositol 3-Kinase/PDK1/mTORC2 and the Pleckstrin Homology Domain to Sustain Malignant Transformation

(2011) Jian-Ping Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rapamycin Suppresses Self-Renewal and Vasculogenic Potential of Stem Cells Isolated from Infantile Hemangioma

(2011) Shoshana Greenberger et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The emerging role of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling network in normal myelopoiesis and leukemogenesis

(2010) Alberto M. Martelli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Akt activation inhibitor TCN-P inhibits Akt phosphorylation by binding to the PH domain of Akt and blocking its recruitment to the plasma membrane

(2010) N Berndt et al.   CELL DEATH AND DIFFERENTIATION

IL-10 inhibits the starvation induced autophagy in macrophages via class I phosphatidylinositol 3-kinase (PI3K) pathway

(2010) Hun-Jung Park et al.   MOLECULAR IMMUNOLOGY

Oral rapamycin attenuates inflammation and enhances stability of atherosclerotic plaques in rabbits independent of serum lipid levels

(2009) Wen Qiang Chen et al.   BRITISH JOURNAL OF PHARMACOLOGY

Heart Disease and Stroke Statistics—2009 Update

(2009) et al.   CIRCULATION

Autophagy in Atherosclerosis

(2009) Wim Martinet et al.   CIRCULATION RESEARCH

From IL-10 to IL-12: how pathogens and their products stimulate APCs to induce TH1 development

(2009) Anne O'Garra et al.   NATURE IMMUNOLOGY

The PI3K–PTEN tug-of-war, oxidative stress and retinal degeneration

(2009) Kyung Hwa Kang et al.   TRENDS IN MOLECULAR MEDICINE

Mammalian Target of Rapamycin Inhibitor Dyslipidemia in Kidney Transplant Recipients

(2008) B. L. Kasiske et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Dominant-negative mutation of monocyte chemoattractant protein-1 prevents vulnerable plaques from rupture in rabbits independent of serum lipid levels

(2008) Lin Zhong et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Tumor Necrosis Factor Blockers Influence Macrophage Responses toMycobacterium tuberculosis

(2008) James Harris et al.   JOURNAL OF INFECTIOUS DISEASES

Inhibition of PI3K-AKT-mTOR Signaling Sensitizes Melanoma Cells to Cisplatin and Temozolomide

(2008) Tobias Sinnberg et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY