Molecular Evolution of Multiple-Level Control of Heme Biosynthesis Pathway in Animal Kingdom

Erythroid Heme Biosynthesis and Its Disorders

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Stanniocalcin 2, forms a complex with heme oxygenase 1, binds hemin and is a heat shock protein

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Mammalian iron metabolism and its control by iron regulatory proteins

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Cellular and mitochondrial iron homeostasis in vertebrates

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Predicting cell-type-specific gene expression from regions of open chromatin

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Fish Lateral Line Innovation: Insights into the Evolutionary Genomic Dynamics of a Unique Mechanosensory Organ

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Divergent Evolutionary Pattern of Starch Biosynthetic Pathway Genes in Grasses and Dicots

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Evolution of Flux Control in the Glucosinolate Pathway in Arabidopsis thaliana

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An expansive human regulatory lexicon encoded in transcription factor footprints

(2012) Shane Neph et al.   NATURE

The accessible chromatin landscape of the human genome

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Differential Selection on Carotenoid Biosynthesis Genes as a Function of Gene Position in the Metabolic Pathway: A Study on the Carrot and Dicots

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Fe2+ binds iron responsive element-RNA, selectively changing protein-binding affinities and regulating mRNA repression and activation

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Control of intracellular heme levels: Heme transporters and heme oxygenases

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Iron sensing and signalling

(2011) Rayko Evstatiev et al.   GUT

Identification of a novel, tissue-specific ABCG2 promoter expressed in pediatric acute megakaryoblastic leukemia

(2011) Patrick K. Campbell et al.   LEUKEMIA RESEARCH

MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

(2011) K. Tamura et al.   MOLECULAR BIOLOGY AND EVOLUTION

Using the Acropora digitifera genome to understand coral responses to environmental change

(2011) Chuya Shinzato et al.   NATURE

ENCODE whole-genome data in the UCSC Genome Browser: update 2012

(2011) K. R. Rosenbloom et al.   NUCLEIC ACIDS RESEARCH

The UCSC Genome Browser database: extensions and updates 2011

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A User's Guide to the Encyclopedia of DNA Elements (ENCODE)

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The Translation Initiation Factor eIF4E Regulates the Sex-Specific Expression of the Master Switch Gene Sxl in Drosophila melanogaster

(2011) Patricia L. Graham et al.   PLoS Genetics

A global role for KLF1 in erythropoiesis revealed by ChIP-seq in primary erythroid cells

(2010) M. R. Tallack et al.   GENOME RESEARCH

Genome-wide identification of TAL1's functional targets: Insights into its mechanisms of action in primary erythroid cells

(2010) M. T. Kassouf et al.   GENOME RESEARCH

Networking erythropoiesis: Figure 1.

(2010) Marc A. Kerenyi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Molecular Evolution and Network-Level Analysis of the N-Glycosylation Metabolic Pathway Across Primates

(2010) L. Montanucci et al.   MOLECULAR BIOLOGY AND EVOLUTION

The dynamic genome of Hydra

(2010) Jarrod A. Chapman et al.   NATURE

SIREs: searching for iron-responsive elements

(2010) M. Campillos et al.   NUCLEIC ACIDS RESEARCH

Structure and function of enzymes in heme biosynthesis

(2010) Gunhild Layer et al.   PROTEIN SCIENCE

New Algorithms and Methods to Estimate Maximum-Likelihood Phylogenies: Assessing the Performance of PhyML 3.0

(2010) Stéphane Guindon et al.   SYSTEMATIC BIOLOGY

Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences

(2010) Jeremy Goecks et al.   GENOME BIOLOGY

Evolutionary rate patterns of the Gibberellin pathway genes

(2009) Yan-hua Yang et al.   BMC EVOLUTIONARY BIOLOGY

Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression

(2009) Y. Cheng et al.   GENOME RESEARCH

The Correlation of Evolutionary Rate with Pathway Position in Plant Terpenoid Biosynthesis

(2009) Heather Ramsay et al.   MOLECULAR BIOLOGY AND EVOLUTION

The biochemistry of heme biosynthesis

(2008) Ilka U. Heinemann et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Elucidation of the Heme Binding Site of Heme-regulated Eukaryotic Initiation Factor 2α Kinase and the Role of the Regulatory Motif in Heme Sensing by Spectroscopic and Catalytic Studies of Mutant Proteins

(2008) Jotaro Igarashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Variation in Constraint Versus Positive Selection as an Explanation for Evolutionary Rate Variation Among Anthocyanin Genes

(2008) Mark D. Rausher et al.   JOURNAL OF MOLECULAR EVOLUTION

A Novel Heme-Regulatory Motif Mediates Heme-Dependent Degradation of the Circadian Factor Period 2

(2008) J. Yang et al.   MOLECULAR AND CELLULAR BIOLOGY