A20 Is Critical for the Induction of Pam3CSK4-Tolerance in Monocytic THP-1 Cells

Toll-Like Receptor-Mediated Production of IL-1Ra Is Negatively Regulated by GSK3 via the MAPK ERK1/2

(2014) K. Rehani et al.   JOURNAL OF IMMUNOLOGY

IFN-  Production by TLR4-Stimulated Innate Immune Cells Is Negatively Regulated by GSK3- 

(2014) H. Wang et al.   JOURNAL OF IMMUNOLOGY

Protective effect of naringenin against experimental colitis via suppression of Toll-like receptor 4/NF-κB signalling

(2013) Wei Dou et al.   BRITISH JOURNAL OF NUTRITION

Polo-Like Kinase 1 (PLK1) Is Involved in Toll-like Receptor (TLR)-Mediated TNF-α Production in Monocytic THP-1 Cells

(2013) Jinyue Hu et al.   PLoS One

Attenuated TLR4/MAPK signaling in monocytes from patients with CRMO results in impaired IL-10 expression

(2012) Sigrun R. Hofmann et al.   CLINICAL IMMUNOLOGY

Regulation of TLR2-Mediated Tolerance and Cross-Tolerance through IRAK4 Modulation by miR-132 and miR-212

(2012) M. A. Nahid et al.   JOURNAL OF IMMUNOLOGY

Leishmania donovani Exploits Host Deubiquitinating Enzyme A20, a Negative Regulator of TLR Signaling, To Subvert Host Immune Response

(2012) S. Srivastav et al.   JOURNAL OF IMMUNOLOGY

A20 (TNFAIP3) Alleviates CVB3-Induced Myocarditis via Inhibiting NF-κB Signaling

(2012) Jun Gui et al.   PLoS One

Endotoxin Tolerance Impairs IL-1 Receptor-Associated Kinase (IRAK) 4 and TGF-β-activated Kinase 1 Activation, K63-linked Polyubiquitination and Assembly of IRAK1, TNF Receptor-associated Factor 6, and IκB Kinase γ and Increases A20 Expression

(2011) Yanbao Xiong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Toll-like Receptor 3 (TLR3) Induces Apoptosis via Death Receptors and Mitochondria by Up-regulating the Transactivating p63 Isoform α (TAP63α)

(2011) Ruili Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycogen synthase kinase 3 involvement in the excessive proinflammatory response to LPS in patients with decompensated cirrhosis

(2011) Nicolas Coant et al.   JOURNAL OF HEPATOLOGY

Induction of endotoxin tolerance in vivo inhibits activation of IRAK4 and increases negative regulators IRAK-M, SHIP-1, and A20

(2011) Yanbao Xiong et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Tumor necrosis factor induces GSK3 kinase–mediated cross-tolerance to endotoxin in macrophages

(2011) Sung Ho Park et al.   NATURE IMMUNOLOGY

Endotoxin tolerance and cross-tolerance in mast cells involves TLR4, TLR2 and FcεR1 interactions and SOCS expression: perspectives on immunomodulation in infectious and allergic diseases

(2010) Saulo F Saturnino et al.   BMC INFECTIOUS DISEASES

Kalopanaxsaponin A ameliorates experimental colitis in mice by inhibiting IRAK-1 activation in the NF-κB and MAPK pathways

(2010) Eun-Ha Joh et al.   BRITISH JOURNAL OF PHARMACOLOGY

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Inhibition of NF- B Signaling by A20 Through Disruption of Ubiquitin Enzyme Complexes

(2010) N. Shembade et al.   SCIENCE

Glycogen synthase kinase-3 promotes the synergistic action of interferon-γ on lipopolysaccharide-induced IL-6 production in RAW264.7 cells

(2009) Eléonore Beurel et al.   CELLULAR SIGNALLING

A20 is an early responding negative regulator of Toll-like receptor 5 signalling in intestinal epithelial cells during inflammation

(2009) N. Oshima et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Adiponectin Promotes Endotoxin Tolerance in Macrophages by Inducing IRAK-M Expression

(2009) Vassiliki Zacharioudaki et al.   JOURNAL OF IMMUNOLOGY

In Vivo Lipopolysaccharide Exposure of Human Blood Leukocytes Induces Cross-Tolerance to Multiple TLR Ligands

(2009) A. F. de Vos et al.   JOURNAL OF IMMUNOLOGY

Ubiquitin-Editing Enzyme A20 Promotes Tolerance to Lipopolysaccharide in Enterocytes

(2009) J. Wang et al.   JOURNAL OF IMMUNOLOGY

Endotoxin tolerance: new mechanisms, molecules and clinical significance

(2009) Subhra K. Biswas et al.   TRENDS IN IMMUNOLOGY

Innate and adaptive immune responses regulated by glycogen synthase kinase-3 (GSK3)

(2009) Eléonore Beurel et al.   TRENDS IN IMMUNOLOGY

Host Innate Immune Receptors and Beyond: Making Sense of Microbial Infections

(2008) Ken J. Ishii et al.   Cell Host & Microbe

Homeostatic MyD88-dependent signals cause lethal inflamMation in the absence of A20

(2008) Emre E. Turer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Up-Regulation of IRAK-M is Essential for Endotoxin Tolerance Induced by a Low Dose of Lipopolysaccharide in Kupffer Cells

(2008) Zuo-Jin Liu et al.   JOURNAL OF SURGICAL RESEARCH

Measles virus P protein suppresses Toll-like receptor signal through up-regulation of ubiquitin-modifying enzyme A20

(2007) Shin-ichi Yokota et al.   FASEB JOURNAL

Glycogen synthase kinase-3beta suppresses tumor necrosis factor-alpha expression in cardiomyocytes during lipopolysaccharide stimulation

(2007) E. Shen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY