Article
Geochemistry & Geophysics
Juan Sebastian Zuluaga-Morales, Maria Victoria Bolanos-Carmona, Carolina Cecilia Cifuentes-Jimenez, Pedro Alvarez-Lloret
Summary: In vitro simulation of natural caries is important for dental research. This study aims to evaluate the effects of pH-cycling on mineral dentine properties and provides a standardized substrate similar to natural residual caries. The results contribute to a better understanding of demineralization mechanisms in an in vivo environment.
Article
Multidisciplinary Sciences
Julie Bethany, Shannon Lynn Johnson, Ferran Garcia-Pichel
Summary: This study describes a novel obligate, intracellular predatory bacterium that preys on soil cyanobacteria in biocrusts, impacting crucial biocrust properties and ecosystem productivity.
NATURE COMMUNICATIONS
(2022)
Article
Biochemistry & Molecular Biology
Olivia Lili Zhang, John Yun Niu, Ollie Yiru Yu, Iris Xiaoxue Yin, May Lei Mei, Chun Hung Chu
Summary: This study investigated the antibiofilm and remineralising effects of peptide GAPI on artificial dentin caries. The results showed that the GAPI group had damaged S. mutans structures, lower colony-forming units, reduced caries depth, decreased mineral loss, and more crystallised hydroxyapatite compared to the control group.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Nutrition & Dietetics
Fiona S. Atkinson, Jouhrah Hussain Khan, Jennie C. Brand-Miller, Joerg Eberhard
Summary: The research suggests that starchy foods, especially those with a high glycemic index (GI), may contribute to an increased risk of dental caries.
Article
Chemistry, Multidisciplinary
Mohammed Alturki, Ulrica Almhoejd, Garrit Koller, Fiona Warburton, Avijit Banerjee
Summary: In this study, the distribution of ester functional groups in carious dentine tissue was compared using high-resolution Raman spectroscopy. The results showed a higher intensity of the ester functional group in the infected dentine zone compared to the affected tissue. This finding has important implications for the development of an objective indicator for the selective operative management of carious dentine.
APPLIED SCIENCES-BASEL
(2022)
Article
Biology
Guadalupe Carolina Barajas-Torres, Miguel Kluender-Kluender, Juan Garduno-Espinosa, Israel Parra-Ortega, Maria Isabel Franco-Hernandez, America Liliana Miranda-Lora
Summary: Sugary soft drinks modify salivary pH and favor bacterial proliferation, contributing to the development of caries. The effects of consuming carbonated drinks without sucrose are limited. However, soft drinks containing aspartame/acesulfame K also promote bacterial proliferation to a lesser extent. Natural water has no significant impact on bacterial proliferation.
Article
Materials Science, Multidisciplinary
Ye Zhang, Ying Huang, Yanyun Pang, Zihui Zhu, Yuchen Zhang, Qing Liu, Xu Zhang, Ying Liu
Summary: This study utilized proanthocyanidins to simulate the bioactivities of glycosaminoglycans, achieving significant effects in promoting dentine remineralization by reconstructing interfibrillar bridges of the collagen network. This strategy not only improved the mechanical properties of demineralized dentine, but also exhibited antibacterial effects, providing new clinical opportunities for the effective treatment of dentine caries.
MATERIALS & DESIGN
(2021)
Article
Dentistry, Oral Surgery & Medicine
Lin Lu Dai, May Lei Mei, Chun Hung Chu, Edward Chin Man Lo
Summary: The study found that the combined use of HX-BGC and fluoride can reduce mineral loss and promote remineralization of demineralized enamel and dentine through the precipitation of newly formed apatite. Adjunctive use of HX-BGC may enhance the remineralization effect of fluoride in the management of early dental caries lesions.
JOURNAL OF DENTISTRY
(2021)
Article
Environmental Sciences
Elizaveta Koroleva, Aza Zizipo Mqulwa, Scott Norris-Jones, Sidney Reed, Zahraa Tambe, Aiden Visagie, Karin Jacobs
Summary: The study revealed that biodegradable cigarette butts had a significant impact on the bacterial community composition of soil compared to non-biodegradable butts, likely due to higher concentrations of certain metals and metalloids in their leachate. Cigarette butts primarily contain microplastics, toxic metals, and metalloids, which can leach into the soil.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Multidisciplinary Sciences
Kaumudi H. Prabhakara, Seppe Kuehn
Summary: Microbial community assembly is a complex process that determines community structure and function. This study investigated how external nutrient supply rate influenced interactions and therefore community assembly. The presence of algae strongly influenced community assembly, leading to convergence of initially diverse bacterial consortia. This study highlights the importance of understanding assembly processes in complex phototroph-heterotroph communities for global ecosystem functioning.
Article
Dentistry, Oral Surgery & Medicine
Nousha Panahpour Eslami, Daniel C. N. Chan, Alireza Sadr
Summary: The study showed that one to two applications of SDF followed by GI coverage can effectively remineralize advanced dentine caries in the presence of artificial saliva, while additional applications did not provide extra benefits. This procedure has the potential to be a treatment option for difficult lesions where conventional restorations would require significant tooth structure removal through traumatic procedures.
JOURNAL OF DENTISTRY
(2021)
Article
Multidisciplinary Sciences
Josep Ramoneda, Elias Stallard-Olivera, Michael Hoffert, Claire C. Winfrey, Masumi Stadler, Juan Pablo Nino-Garcia, Noah Fierer
Summary: We analyzed bacterial distributions in five datasets and identified genes consistently associated with pH preference. We developed a machine learning model to estimate bacterial pH preferences from genomic information.
Article
Nutrition & Dietetics
Rosalyn J. Singleton, Gretchen M. Day, Timothy K. Thomas, Joseph A. Klejka, Christine A. Desnoyers, Melanie N. P. McIntyre, David M. Compton, Kenneth E. Thummel, Robert J. Schroth, Leanne M. Ward, Dane C. Lenaker, Rachel K. Lescher, Joseph B. McLaughlin
Summary: The study found that prenatal vitamin D supplementation in high-risk populations can improve childhood outcomes regarding rickets and dental caries.
Article
Immunology
Florent Malard, Aonghus Lavelle, Giorgia Battipaglia, Beatrice Gaugler, Remy Dulery, Eolia Brissot, Clemence Mediavilla, Sarah Jegou, Nathalie Rolhion, Tounes Ledraa, Razan Mohty, Harry Sokol, Mohamad Mohty
Summary: In patients receiving allogeneic hematopoietic cell transplantation (alloHCT), higher bacterial diversity is associated with improved overall survival and disease-free survival, while high relative abundance of Candida albicans may result in lower survival rates.
MUCOSAL IMMUNOLOGY
(2021)
Article
Ecology
Sarah C. Hill, Sarah Francois, Julien Theze, Adrian L. Smith, Peter Simmonds, Christopher M. Perrins, Lia van der Hoek, Oliver G. Pybus
Summary: Wildlife carries pathogens that can harm human or livestock health and are the source of most emerging infectious diseases. Changes in wildlife population age-structures and age-stratified behaviors can alter the level of pathogen detection within a species and the risk of spillover to other species. By using a metagenomic approach, this study characterized viral and prokaryotic carriage in a healthy wild bird population and identified novel virus species and the core prokaryotic microbiome. The findings suggest that perturbations in wildlife population age-structures could impact the circulation dynamics and spillover risk of microbes, potentially including pathogens.
Article
Health Care Sciences & Services
Chris Degeling, Jane Johnson, Jon Iredell, Ky-Anh Nguyen, Jacqueline M. Norris, John D. Turnidge, Angus Dawson, Stacy M. Carter, Gwendolyn L. Gilbert
HEALTH EXPECTATIONS
(2018)
Article
Biochemical Research Methods
Christina J. Adler, Abbe White, Michelle Bockmann, Gina V. Browne, Grant Townsend, Toby Hughes
JOURNAL OF MICROBIOLOGICAL METHODS
(2018)
Article
Multidisciplinary Sciences
Nano Nagle, Mannis van Oven, Stephen Wilcox, Sheila van Holst Pellekaan, Chris Tyler-Smith, Yali Xue, Kaye N. Ballantyne, Leah Wilcox, Luka Papac, Karen Cooke, Roland A. H. van Oorschot, Peter McAllister, Lesley Williams, Manfred Kayser, R. John Mitchell
SCIENTIFIC REPORTS
(2017)
Article
Microbiology
Jacquelyn M. Fechney, Gina V. Browne, Neeta Prabhu, Laszlo Irinyi, Wieland Meyer, Toby Hughes, Michelle Bockmann, Grant Townsend, Hanieh Salehi, Christina J. Adler
JOURNAL OF ORAL MICROBIOLOGY
(2019)
Article
Biochemistry & Molecular Biology
Laura S. Weyrich, Andrew G. Farrer, Raphael Eisenhofer, Luis A. Arriola, Jennifer Young, Caitlin A. Selway, Matilda Handsley-Davis, Christina J. Adler, James Breen, Alan Cooper
MOLECULAR ECOLOGY RESOURCES
(2019)
Article
Biochemistry & Molecular Biology
Florian Veillard, Maryta Sztukowska, Zuzanna Nowakowska, Danuta Mizgalska, Ida B. Thogersen, Jan J. Enghild, Matthew Bogyo, Barbara Potempa, Ky-Anh Nguyen, Jan Potempa
Review
Dentistry, Oral Surgery & Medicine
S. Sukumar, F. E. Martin, T. E. Hughes, C. J. Adler
AUSTRALIAN DENTAL JOURNAL
(2020)
Article
Multidisciplinary Sciences
Xiaoyan Zhou, Shanika Nanayakkara, Jin-Long Gao, Ky-Anh Nguyen, Christina J. Adler
SCIENTIFIC REPORTS
(2019)
Article
Dentistry, Oral Surgery & Medicine
Ky-Anh Nguyen, Cherie Lucas, Delyse Leadbeatter
EUROPEAN JOURNAL OF DENTAL EDUCATION
(2020)
Article
Psychology, Biological
Carra A. Simpson, Christina Adler, Mieke R. du Plessis, Elizabeth R. Landau, Stuart G. Dashper, Eric C. Reynolds, Orli S. Schwartz, Julian G. Simmons
PHYSIOLOGY & BEHAVIOR
(2020)
Article
Biochemistry & Molecular Biology
Christina Jane Adler, Kim-Anh Le Cao, Toby Hughes, Piyush Kumar, Christine Austin
Summary: The first 1000 days of life play a crucial role in shaping the oral microbiome and oral health. However, technological limitations and statistical methods have been barriers to studying the impact of early life exposures on the oral microbiome. Understanding how early life exposures influence the oral microbiome can lead to interventions to reduce dental decay prevalence.
Correction
Biochemistry & Molecular Biology
Begona Martinez-Cruz, Isabel Mendizabal, Christine Harmant, Rosario de Pablo, Mihai Ioana, Dora Angelicheva, Anastasia Kouvatsi, Halyna Makukh, Mihai G. Netea, Horolma Pamjav, Andrea Zalan, Ivailo Tournev, Elena Marushiakova, Vesselin Popov, Jaume Bertranpetit, Luba Kalaydjieva, Lluis Quintana-Murci, David Comas
EUROPEAN JOURNAL OF HUMAN GENETICS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Joerg Eberhard, Kate Ruiz, Jian Tan, Thilini N. Jayasinghe, Shahrukh Khan, Elif Eroglu, Christina Adler, Stephen J. Simpson, David G. Le Couteur, David Raubenheimer, Laurence Macia, Alison K. Gosby, Rosilene Ribeiro
Summary: The aim of this study was to assess the effects of two macronutrient interventions on oral health. The results showed that a semi-vegetarian high-fat diet had positive effects on clinical parameters of periodontal health.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2022)
Article
Multidisciplinary Sciences
Smitha Sukumar, Fang Wang, Carra A. Simpson, Cali E. Willet, Tracy Chew, Toby E. Hughes, Michelle R. Bockmann, Rosemarie Sadsad, F. Elizabeth Martin, Henry W. Lydecker, Gina V. Browne, Kylie M. Davis, Minh Bui, Elena Martinez, Christina J. Adler
Summary: In this study, the authors conducted a genetic surveillance of the antimicrobial resistance potential of the human oral microbiome in the first decade of life. They found that the oral microbiome undergoes dynamic changes influenced by tooth decay, leading to increased potential for gene mobilization as children grow. The presence and mobilization of antimicrobial resistance genes (ARGs) in the oral microbiome highlight the importance of surveillance to combat antimicrobial resistance (AMR).
NATURE COMMUNICATIONS
(2023)