TL1A Induces TCR Independent IL-6 and TNF-α Production and Growth of PLZF+ Leukocytes

Helminth therapy and multiple sclerosis

(2013) J.O. Fleming   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Cytokine activation induces human memory-like NK cells

(2012) R. Romee et al.   BLOOD

Death receptor 3 is essential for generating optimal protective CD41 T-cell immunity against Salmonella

(2012) Sarah L. Buchan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The death receptor 3/TL1A pathway is essential for efficient development of antiviral CD4+ and CD8+ T-cell immunity

(2012) Jason P. Twohig et al.   FASEB JOURNAL

Increased levels of soluble TNF-like cytokine 1A in ankylosing spondylitis

(2012) M. Konsta et al.   RHEUMATOLOGY

Cytokine-induced cytokine production by conventional and innate lymphoid cells

(2012) Liying Guo et al.   TRENDS IN IMMUNOLOGY

Development of PLZF-expressing innate T cells

(2011) Eric S Alonzo et al.   CURRENT OPINION IN IMMUNOLOGY

IL-6 signaling in autoimmunity, chronic inflammation and inflammation-associated cancer

(2011) Markus F. Neurath et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Differential expression of the TL1A/DcR3 system of TNF/TNFR-like proteins in large vs. small intestinal Crohn's disease

(2011) Giorgos Bamias et al.   DIGESTIVE AND LIVER DISEASE

Upregulation and nuclear localization of TNF-like Cytokine 1A (TL1A) and its receptors DR3 and DcR3 in psoriatic skin lesions

(2011) Giorgos Bamias et al.   EXPERIMENTAL DERMATOLOGY

Stat3 Phosphorylation Mediates Resistance of Primary Human T Cells to Regulatory T Cell Suppression

(2011) W. A. Goodman et al.   JOURNAL OF IMMUNOLOGY

Monocytes differentiated with GM-CSF and IL-15 initiate Th17 and Th1 responses that are contact-dependent and mediated by IL-15

(2011) Kristina M. Harris   JOURNAL OF LEUKOCYTE BIOLOGY

Disturbed Th17/Treg balance in patients with rheumatoid arthritis

(2011) Qian Niu et al.   RHEUMATOLOGY INTERNATIONAL

Virally infected and matured human dendritic cells activate natural killer cells via cooperative activity of plasma membrane-bound TNF and IL-15

(2010) L. Vujanovic et al.   BLOOD

Th17 and Regulatory T Cells in Mediating and Restraining Inflammation

(2010) Dan R. Littman et al.   CELL

Bystander activation of CD4+T cells

(2010) Onur Boyman   EUROPEAN JOURNAL OF IMMUNOLOGY

Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation

(2010) Gareth W. Jones et al.   FASEB JOURNAL

IL-15 induces CD8+ T cells to acquire functional NK receptors capable of modulating cytotoxicity and cytokine secretion

(2010) Margareta P. Correia et al.   IMMUNOBIOLOGY

Interleukin-6: From identification of the cytokine to development of targeted treatments

(2010) Eric Assier et al.   JOINT BONE SPINE

PLZF Induces the Spontaneous Acquisition of Memory/Effector Functions in T Cells Independently of NKT Cell-Related Signals

(2010) D. Kovalovsky et al.   JOURNAL OF IMMUNOLOGY

The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling

(2010) Hergen Spits et al.   NATURE IMMUNOLOGY

T cells expressing the transcription factor PLZF regulate the development of memory-like CD8+ T cells

(2010) Michael A Weinreich et al.   NATURE IMMUNOLOGY

TL1A in the inflammatory network in autoimmune diseases

(2010) Jagadeesh Bayry   Nature Reviews Rheumatology

IL-15 is critical for the maintenance and innate functions of self-specific CD8+T cells

(2009) Momoe Itsumi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Generation of PLZF+CD4+T cells via MHC class II–dependent thymocyte–thymocyte interaction is a physiological process in humans

(2009) You Jeong Lee et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Role of TL1A in the Pathogenesis of Rheumatoid Arthritis

(2009) J. Zhang et al.   JOURNAL OF IMMUNOLOGY

IL-15 Renders Conventional Lymphocytes Resistant to Suppressive Functions of Regulatory T Cells through Activation of the Phosphatidylinositol 3-Kinase Pathway

(2009) M. B. Ahmed et al.   JOURNAL OF IMMUNOLOGY

IL-6 Signaling in Psoriasis Prevents Immune Suppression by Regulatory T Cells

(2009) W. A. Goodman et al.   JOURNAL OF IMMUNOLOGY

IL-21 and IL-15 cytokine DNA augments HSV specific effector and memory CD8+ T cell response

(2009) Luiz Rodrigues et al.   MOLECULAR IMMUNOLOGY

Integration of cytokine and heterologous receptor signaling pathways

(2009) Jelena S Bezbradica et al.   NATURE IMMUNOLOGY

TCR-inducible PLZF transcription factor required for innate phenotype of a subset of    T cells with restricted TCR diversity

(2009) T. Kreslavsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: results from a 24-week multicentre randomised placebo-controlled trial

(2008) P. Emery et al.   ANNALS OF THE RHEUMATIC DISEASES

Circulating levels of TNF-like cytokine 1A (TL1A) and its decoy receptor 3 (DcR3) in rheumatoid arthritis

(2008) Giorgos Bamias et al.   CLINICAL IMMUNOLOGY

The TNF-Family Receptor DR3 is Essential for Diverse T Cell-Mediated Inflammatory Diseases

(2008) Françoise Meylan et al.   IMMUNITY

The Transcription Factor PLZF Directs the Effector Program of the NKT Cell Lineage

(2008) Adam K. Savage et al.   IMMUNITY

Essential role of TNF receptor superfamily 25 (TNFRSF25) in the development of allergic lung inflammation

(2008) Lei Fang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Death Receptor 3–TNF-like protein 1A pathway drives adverse bone pathology in inflammatory arthritis

(2008) Melanie Jane Bull et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TL1A–DR3 interaction regulates Th17 cell function and Th17-mediated autoimmune disease

(2008) Bhanu P. Pappu et al.   JOURNAL OF EXPERIMENTAL MEDICINE