No Correlation between PNPLA3 rs738409 Genotype and Fatty Liver and Hepatic Cirrhosis in Japanese Patients with HCV

Genome-wide scan revealed that polymorphisms in the PNPLA3, SAMM50, and PARVB genes are associated with development and progression of nonalcoholic fatty liver disease in Japan

(2013) Takuya Kitamoto et al.   HUMAN GENETICS

Lipopolysaccharide blocks induction of unfolded protein response in human hepatoma cell lines

(2013) Xia Jiang et al.   IMMUNOLOGY LETTERS

Alanine Aminotransferase Elevation during Peginterferon Alpha-2a or Alpha-2b plus Ribavirin Treatment

(2013) Masato Nakamura et al.   International Journal of Medical Sciences

Prevalence of Hepatitis C Virus Subgenotypes 1a and 1b in Japanese Patients: Ultra-Deep Sequencing Analysis of HCV NS5B Genotype-Specific Region

(2013) Shuang Wu et al.   PLoS One

Real-Time Ultrasound Attenuation Imaging of Diffuse Fatty Liver Disease

(2013) Yuko Kanayama et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Genetic Polymorphisms of the Human PNPLA3 Gene Are Strongly Associated with Severity of Non-Alcoholic Fatty Liver Disease in Japanese

(2012) Takahisa Kawaguchi et al.   PLoS One

Roles of ITPA and IL28B Genotypes in Chronic Hepatitis C Patients Treated with Peginterferon Plus Ribavirin

(2012) Tatsuo Miyamura et al.   Viruses-Basel

Association of the rs738409 polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease

(2011) Kikuko Hotta et al.   BMC Medical Genetics

Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease

(2011) Silvia Sookoian et al.   HEPATOLOGY

NASH: A global health problem

(2011) Arun J. Sanyal   HEPATOLOGY RESEARCH

Hepatic steatosis and hepatitis C: Still unhappy bedfellows?

(2011) Shinn-Jang Hwang et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Hepatitis C Virus Nonstructural 5A Protein Inhibits Lipopolysaccharide-Mediated Apoptosis of Hepatocytes by Decreasing Expression of Toll-Like Receptor 4

(2011) Ryo Tamura et al.   JOURNAL OF INFECTIOUS DISEASES

Hepatic STAT1-Nuclear Translocation and Interleukin 28B Polymorphisms Predict Treatment Outcomes in Hepatitis C Virus Genotype 1-Infected Patients

(2011) Tatsuo Miyamura et al.   PLoS One

Simple assay based on restriction fragment length polymorphism associated with IL28B in chronic hepatitis C patients

(2011) Shingo Nakamoto et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Evolving epidemiology of hepatitis C virus

(2010) D. Lavanchy   CLINICAL MICROBIOLOGY AND INFECTION

The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease

(2010) Yaron Rotman et al.   HEPATOLOGY

Reliability of transient elastography for the detection of fibrosis in Non-Alcoholic Fatty Liver Disease and chronic viral hepatitis

(2010) Silvia Gaia et al.   JOURNAL OF HEPATOLOGY

IL-28B rs12979860 C/T allele distribution in patients with liver cirrhosis: Role in the course of chronic viral hepatitis and the development of HCC

(2010) Carlo Fabris et al.   JOURNAL OF HEPATOLOGY

Hepatitis C virus protein and iron overload induce hepatic steatosis through the unfolded protein response in mice

(2010) Sohji Nishina et al.   LIVER INTERNATIONAL

A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans

(2009) A. Kotronen et al.   DIABETOLOGIA

Morbid obesity exposes the association between PNPLA3 I148M (rs738409) and indices of hepatic injury in individuals of European descent

(2009) S Romeo et al.   INTERNATIONAL JOURNAL OF OBESITY

A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis

(2009) Shaoqing He et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiple variants in toll-like receptor 4 gene modulate risk of liver fibrosis in Caucasians with chronic hepatitis C infection

(2009) Yonghong Li et al.   JOURNAL OF HEPATOLOGY

Functional linkage of cirrhosis-predictive single nucleotide polymorphisms of toll-like receptor 4 to hepatic stellate cell responses

(2008) Jinsheng Guo et al.   HEPATOLOGY

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

(2008) Stefano Romeo et al.   NATURE GENETICS