Autophagy Controls an Intrinsic Host Defense to Bacteria by Promoting Epithelial Cell Survival: A Murine Model

Maturation of Paneth Cells Induces the Refractory State of Newborn Mice to Shigella Infection

(2014) M.-I. Fernandez et al.   JOURNAL OF IMMUNOLOGY

The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response

(2012) Takahito Sanada et al.   NATURE

A Tecpr1-Dependent Selective Autophagy Pathway Targets Bacterial Pathogens

(2011) Michinaga Ogawa et al.   Cell Host & Microbe

Shigella are versatile mucosal pathogens that circumvent the host innate immune system

(2011) Hiroshi Ashida et al.   CURRENT OPINION IN IMMUNOLOGY

Constitutive intestinal NF-κB does not trigger destructive inflammation unless accompanied by MAPK activation

(2011) Monica Guma et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Manipulation of autophagy by bacteria for their own benefit

(2011) Michinaga Ogawa et al.   MICROBIOLOGY AND IMMUNOLOGY

Autophagy in the intestinal epithelium reduces endotoxin-induced inflammatory responses by inhibiting NF-κB activation

(2010) Yoshimi Fujishima et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Defensins play a crucial role in protecting mice against oral Shigella flexneri infection

(2010) Doo-Hee Shim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Virus-Plus-Susceptibility Gene Interaction Determines Crohn's Disease Gene Atg16L1 Phenotypes in Intestine

(2010) Ken Cadwell et al.   CELL

Bacterial Interactions with the Host Epithelium

(2010) Minsoo Kim et al.   Cell Host & Microbe

Entrapment of Intracytosolic Bacteria by Septin Cage-like Structures

(2010) Serge Mostowy et al.   Cell Host & Microbe

Cell-Cell Propagation of NF-κB Transcription Factor and MAP Kinase Activation Amplifies Innate Immunity against Bacterial Infection

(2010) Christoph Alexander Kasper et al.   IMMUNITY

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

Shigella Targets the Mitochondrial Checkpoint of Programmed Necrosis

(2009) Lorenzo Galluzzi et al.   Cell Host & Microbe

Shigella Phagocytic Vacuolar Membrane Remnants Participate in the Cellular Response to Pathogen Invasion and Are Regulated by Autophagy

(2009) Nicolas Dupont et al.   Cell Host & Microbe

Shigella Induces Mitochondrial Dysfunction and Cell Death in Nonmyleoid Cells

(2009) Leticia A.M. Carneiro et al.   Cell Host & Microbe

Bacteria hijack integrin-linked kinase to stabilize focal adhesions and block cell detachment

(2009) Minsoo Kim et al.   NATURE

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

(2009) Leonardo H Travassos et al.   NATURE IMMUNOLOGY

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

(2008) Ken Cadwell et al.   NATURE

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production

(2008) Tatsuya Saitoh et al.   NATURE

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE