A p53 Drug Response Signature Identifies Prognostic Genes in High-Risk Neuroblastoma

Mdm2 Deficiency Suppresses MYCN-Driven Neuroblastoma Tumorigenesis In Vivo

(2015) Zaowen Chen et al.   NEOPLASIA

RRM2 Regulates Bcl-2 in Head and Neck and Lung Cancers: A Potential Target for Cancer Therapy

(2013) M. A. Rahman et al.   CLINICAL CANCER RESEARCH

Differential Processing of let-7a Precursors Influences RRM2 Expression and Chemosensitivity in Pancreatic Cancer: Role of LIN-28 and SET Oncoprotein

(2013) Yangzom Doma Bhutia et al.   PLoS One

Distinct p53 genomic binding patterns in normal and cancer-derived human cells

(2012) Krassimira Botcheva et al.   CELL CYCLE

Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes

(2012) Jan J. Molenaar et al.   NATURE

Initial testing of the MDM2 inhibitor RG7112 by the pediatric preclinical testing program

(2012) Hernan Carol et al.   PEDIATRIC BLOOD & CANCER

Copy number defects of G1-Cell cycle genes in neuroblastoma are frequent and correlate with high expression of E2F target genes and a poor prognosis

(2011) Jan J. Molenaar et al.   GENES CHROMOSOMES & CANCER

Functional Analysis of the p53 Pathway in Neuroblastoma Cells Using the Small-Molecule MDM2 Antagonist Nutlin-3

(2011) T. Van Maerken et al.   MOLECULAR CANCER THERAPEUTICS

Crosstalk between c-Jun and TAp73α/β contributes to the apoptosis–survival balance

(2011) Max Koeppel et al.   NUCLEIC ACIDS RESEARCH

Neuroblastoma genetics and phenotype: A tale of heterogeneity

(2011) Frank Speleman et al.   SEMINARS IN CANCER BIOLOGY

Regulation of Minichromosome Maintenance Gene Family by MicroRNA-1296 and Genistein in Prostate Cancer

(2010) Shahana Majid et al.   CANCER RESEARCH

Combinatorial Regulation of Neuroblastoma Tumor Progression by N-Myc and Hypoxia Inducible Factor HIF-1 

(2010) G. Qing et al.   CANCER RESEARCH

Accurate Outcome Prediction in Neuroblastoma across Independent Data Sets Using a Multigene Signature

(2010) K. De Preter et al.   CLINICAL CANCER RESEARCH

High Frequency of p53/MDM2/p14ARF Pathway Abnormalities in Relapsed Neuroblastoma

(2010) J. Carr-Wilkinson et al.   CLINICAL CANCER RESEARCH

Autophagy regulation by p53

(2010) Maria Chiara Maiuri et al.   CURRENT OPINION IN CELL BIOLOGY

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

(2010) Mark E. Davis et al.   NATURE

miR-380-5p represses p53 to control cellular survival and is associated with poor outcome in MYCN-amplified neuroblastoma

(2010) Alexander Swarbrick et al.   NATURE MEDICINE

Recent Advances in Neuroblastoma

(2010) John M. Maris   NEW ENGLAND JOURNAL OF MEDICINE

p53 Research: The Past Thirty Years and the Next Thirty Years

(2010) D. Lane et al.   Cold Spring Harbor Perspectives in Biology

Identification of a Functional Network of Human Epigenetic Silencing Factors

(2009) Andrey Poleshko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antitumor Activity of the Selective MDM2 Antagonist Nutlin-3 Against Chemoresistant Neuroblastoma With Wild-Type p53

(2009) Tom Van Maerken et al.   JNCI-Journal of the National Cancer Institute

Targeted Molecular Therapy for Neuroblastoma: The ARF/MDM2/p53 Axis

(2009) Eugene Kim et al.   JNCI-Journal of the National Cancer Institute

59-gene prognostic signature sub-stratifies high-risk neuroblastoma patients

(2009) Joëlle Vermeulen et al.   LANCET ONCOLOGY

RDML: structured language and reporting guidelines for real-time quantitative PCR data

(2009) S. Lefever et al.   NUCLEIC ACIDS RESEARCH

Mouse Models of p53 Functions

(2009) G. Lozano   Cold Spring Harbor Perspectives in Biology

The International Neuroblastoma Risk Group (INRG) Classification System: An INRG Task Force Report

(2008) Susan L. Cohn et al.   JOURNAL OF CLINICAL ONCOLOGY

Oncogenic mutations of ALK kinase in neuroblastoma

(2008) Yuyan Chen et al.   NATURE

Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma

(2008) Isabelle Janoueix-Lerosey et al.   NATURE

RTPrimerDB: the portal for real-time PCR primers and probes

(2008) S. Lefever et al.   NUCLEIC ACIDS RESEARCH

High Myc pathway activity and low stage of neuronal differentiation associate with poor outcome in neuroblastoma

(2008) E. Fredlund et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA