How Changes in Extracellular Matrix Mechanics and Gene Expression Variability Might Combine to Drive Cancer Progression

Tumor progression: Chance and necessity in Darwinian and Lamarckian somatic (mutationless) evolution

(2012) Sui Huang   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression

(2011) Mina J Bissell et al.   NATURE MEDICINE

An Off-Lattice Hybrid Discrete-Continuum Model of Tumor Growth and Invasion

(2010) Junhwan Jeon et al.   BIOPHYSICAL JOURNAL

Numerical simulation of tumor-induced angiogenesis influenced by the extra-cellular matrix mechanical environment

(2009) Yan Cai et al.   ACTA MECHANICA SINICA

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Cytoskeletal control of growth and cell fate switching

(2009) Akiko Mammoto et al.   CURRENT OPINION IN CELL BIOLOGY

Non-genetic heterogeneity — a mutation-independent driving force for the somatic evolution of tumours

(2009) Amy Brock et al.   NATURE REVIEWS GENETICS

3D Multi-Cell Simulation of Tumor Growth and Angiogenesis

(2009) Abbas Shirinifard et al.   PLoS One

Regulated Fluctuations in Nanog Expression Mediate Cell Fate Decisions in Embryonic Stem Cells

(2009) Tibor Kalmar et al.   PLOS BIOLOGY

Noise-Driven Stem Cell and Progenitor Population Dynamics

(2008) Martin Hoffmann et al.   PLoS One

Invasion emerges from cancer cell adaptation to competitive microenvironments: Quantitative predictions from multiscale mathematical models

(2008) Vito Quaranta et al.   SEMINARS IN CANCER BIOLOGY

Can cancer be reversed by engineering the tumor microenvironment?

(2008) Donald E. Ingber   SEMINARS IN CANCER BIOLOGY

Topology of the heterogeneous nature of the extracellular matrix on stochastic modeling of tumor-induced angiogenesis

(2007) Franck Amyot et al.   MICROVASCULAR RESEARCH