B Cell Responses to HIV Antigen Are a Potent Correlate of Viremia in HIV-1 Infection and Improve with PD-1 Blockade

Human Circulating PD-1+CXCR3−CXCR5+ Memory Tfh Cells Are Highly Functional and Correlate with Broadly Neutralizing HIV Antibody Responses

(2013) Michela Locci et al.   IMMUNITY

Inadequate T follicular cell help impairs B cell immunity during HIV infection

(2013) Rafael A Cubas et al.   NATURE MEDICINE

Antiretroviral Therapy Reduces the Magnitude and T Cell Receptor Repertoire Diversity of HIV-Specific T Cell Responses without Changing T Cell Clonotype Dominance

(2012) Joseph A. Conrad et al.   JOURNAL OF VIROLOGY

Responsiveness of HIV-specific CD4 T cells to PD-1 blockade

(2011) F. Porichis et al.   BLOOD

SIV infection of rhesus macaques results in dysfunctional T- and B-cell responses to neo and recall Leishmania major vaccination

(2011) N. R. Klatt et al.   BLOOD

Interleukin-2 Production by Polyfunctional HIV-1–Specific CD8 T Cells Is Associated With Enhanced Viral Suppression

(2011) Olusimidele T Akinsiku et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Attenuation of HIV-associated human B cell exhaustion by siRNA downregulation of inhibitory receptors

(2011) Lela Kardava et al.   JOURNAL OF CLINICAL INVESTIGATION

Dominant Clonotypes within HIV-Specific T Cell Responses Are Programmed Death-1high and CD127low and Display Reduced Variant Cross-Reactivity

(2011) J. A. Conrad et al.   JOURNAL OF IMMUNOLOGY

Moving ahead an HIV vaccine: Use both arms to beat HIV

(2011) Bruce D Walker et al.   NATURE MEDICINE

Elevated frequencies of highly activated CD4+ T cells in HIV+ patients developing immune reconstitution inflammatory syndrome

(2010) L. R. V. Antonelli et al.   BLOOD

Revisiting Immune Exhaustion During HIV Infection

(2010) Alka Khaitan et al.   Current HIV/AIDS Reports

Loss of HIV-specific memory B-cells as a potential mechanism for the dysfunction of the humoral immune response against HIV

(2009) Bianca M. Bussmann et al.   VIROLOGY

Activation drives PD-1 expression during vaccine-specific proliferation and following lentiviral infection in macaques

(2008) David A. Hokey et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Lytic Granule Loading of CD8+ T Cells Is Required for HIV-Infected Cell Elimination Associated with Immune Control

(2008) Stephen A. Migueles et al.   IMMUNITY

Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

(2008) R. Brad Jones et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals

(2008) Susan Moir et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Enhancing SIV-specific immunity in vivo by PD-1 blockade

(2008) Vijayakumar Velu et al.   NATURE