Correcting for Population Structure and Kinship Using the Linear Mixed Model: Theory and Extensions

Mixed models can correct for population structure for genomic regions under selection

(2013) Jae Hoon Sul et al.   NATURE REVIEWS GENETICS

Polygenic Modeling with Bayesian Sparse Linear Mixed Models

(2013) Xiang Zhou et al.   PLoS Genetics

Degrees of freedom in lasso problems

(2012) Ryan J. Tibshirani et al.   ANNALS OF STATISTICS

On p-values for smooth components of an extended generalized additive model

(2012) S. N. Wood   BIOMETRIKA

Inferences from Genomic Models in Stratified Populations

(2012) L. Janss et al.   GENETICS

Heritability in the genome-wide association era

(2012) Noah Zaitlen et al.   HUMAN GENETICS

Rapid variance components–based method for whole-genome association analysis

(2012) Gulnara R Svishcheva et al.   NATURE GENETICS

An efficient multi-locus mixed-model approach for genome-wide association studies in structured populations

(2012) Vincent Segura et al.   NATURE GENETICS

Genome-wide efficient mixed-model analysis for association studies

(2012) Xiang Zhou et al.   NATURE GENETICS

Improved linear mixed models for genome-wide association studies

(2012) Jennifer Listgarten et al.   NATURE METHODS

The nature of confounding in genome-wide association studies

(2012) Bjarni J. Vilhjálmsson et al.   NATURE REVIEWS GENETICS

Evolution and Functional Impact of Rare Coding Variation from Deep Sequencing of Human Exomes

(2012) J. A. Tennessen et al.   SCIENCE

An Abundance of Rare Functional Variants in 202 Drug Target Genes Sequenced in 14,002 People

(2012) M. R. Nelson et al.   SCIENCE

Recent Explosive Human Population Growth Has Resulted in an Excess of Rare Genetic Variants

(2012) A. Keinan et al.   SCIENCE

Population Structure Can Inflate SNP-Based Heritability Estimates

(2011) Sharon R. Browning et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Comparison of Association Methods Correcting for Population Stratification in Case-Control Studies

(2011) Chengqing Wu et al.   ANNALS OF HUMAN GENETICS

A Bivariate Genome-Wide Approach to Metabolic Syndrome: STAMPEED Consortium

(2011) A. T. Kraja et al.   DIABETES

FaST linear mixed models for genome-wide association studies

(2011) Christoph Lippert et al.   NATURE METHODS

Penalized wavelets: Embedding wavelets into semiparametric regression

(2011) M.P. Wand et al.   Electronic Journal of Statistics

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genetic Variants Influencing Circulating Lipid Levels and Risk of Coronary Artery Disease

(2010) Dawn M. Waterworth et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Control of Population Stratification by Correlation-Selected Principal Components

(2010) Seunggeun Lee et al.   BIOMETRICS

SNP Selection in genome-wide and candidate gene studies via penalized logistic regression

(2010) Kristin L. Ayers et al.   GENETIC EPIDEMIOLOGY

Genomic Similarity and Kernel Methods II: Methods for Genomic Information

(2010) Daniel J. Schaid   HUMAN HEREDITY

Genomic Similarity and Kernel Methods I: Advancements by Building on Mathematical and Statistical Foundations

(2010) Daniel J. Schaid   HUMAN HEREDITY

Increased power of mixed models facilitates association mapping of 10 loci for metabolic traits in an isolated population

(2010) E. E. Kenny et al.   HUMAN MOLECULAR GENETICS

Genetic causes of high and low serum HDL-cholesterol

(2010) Daphna Weissglas-Volkov et al.   JOURNAL OF LIPID RESEARCH

Hundreds of variants clustered in genomic loci and biological pathways affect human height

(2010) Hana Lango Allen et al.   NATURE

Common SNPs explain a large proportion of the heritability for human height

(2010) Jian Yang et al.   NATURE GENETICS

Mixed linear model approach adapted for genome-wide association studies

(2010) Zhiwu Zhang et al.   NATURE GENETICS

Variance component model to account for sample structure in genome-wide association studies

(2010) Hyun Min Kang et al.   NATURE GENETICS

New approaches to population stratification in genome-wide association studies

(2010) Alkes L. Price et al.   NATURE REVIEWS GENETICS

Population Structure and Cryptic Relatedness in Genetic Association Studies

(2010) William Astle et al.   STATISTICAL SCIENCE

Model selection using modified AIC and BIC in joint modeling of paired functional data

(2010) Jiawei Wei et al.   STATISTICS & PROBABILITY LETTERS

A Genealogical Interpretation of Principal Components Analysis

(2009) Gil McVean   PLoS Genetics

Efficient Control of Population Structure in Model Organism Association Mapping

(2008) H. M. Kang et al.   GENETICS

Interpreting principal component analyses of spatial population genetic variation

(2008) John Novembre et al.   NATURE GENETICS

Heritability in the genomics era — concepts and misconceptions

(2008) Peter M. Visscher et al.   NATURE REVIEWS GENETICS

Simultaneous Analysis of All SNPs in Genome-Wide and Re-Sequencing Association Studies

(2008) Clive J. Hoggart et al.   PLoS Genetics