Epstein-Barr Virus_Encoded LMP1 Upregulates MicroRNA-21 to Promote the Resistance of Nasopharyngeal Carcinoma Cells to Cisplatin-Induced Apoptosis by Suppressing PDCD4 and Fas-L
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Title
Epstein-Barr Virus_Encoded LMP1 Upregulates MicroRNA-21 to Promote the Resistance of Nasopharyngeal Carcinoma Cells to Cisplatin-Induced Apoptosis by Suppressing PDCD4 and Fas-L
Authors
Keywords
Apoptosis, Nasopharyngeal carcinoma, Epstein-Barr virus, Immunoblotting, Cell staining, MicroRNAs, Gene expression, Transfection
Journal
PLoS One
Volume 8, Issue 10, Pages e78355
Publisher
Public Library of Science (PLoS)
Online
2013-10-24
DOI
10.1371/journal.pone.0078355
References
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Note: Only part of the references are listed.- Cross-Linking of B7-H1 on EBV-Transformed B Cells Induces Apoptosis through Reactive Oxygen Species Production, JNK Signaling Activation, and fasL Expression
- (2014) Y. S. Kim et al. JOURNAL OF IMMUNOLOGY
- LMP1-Induced Cell Death May Contribute to the Emergency of Its Oncogenic Property
- (2014) Guillaume Brocqueville et al. PLoS One
- Viral oncoprotein LMP1 disrupts p53-induced cell cycle arrest and apoptosis through modulating K63-linked ubiquitination of p53
- (2012) Lili Li et al. CELL CYCLE
- EBV and human microRNAs co-target oncogenic and apoptotic viral and human genes during latency
- (2012) Kasandra J Riley et al. EMBO JOURNAL
- Comparison of five cisplatin-based regimens frequently used as the first-line protocols in metastatic nasopharyngeal carcinoma
- (2012) Ying Jin et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- The Latent Membrane Protein 1 (LMP1) Oncogene of Epstein-Barr Virus Can Simultaneously Induce and Inhibit Apoptosis in B Cells
- (2012) Zachary L. Pratt et al. JOURNAL OF VIROLOGY
- Differential regulation of miR-21 and miR-146a by Epstein–Barr virus-encoded EBNA2
- (2012) P Rosato et al. LEUKEMIA
- The role of the EBV-encoded latent membrane proteins LMP1 and LMP2 in the pathogenesis of nasopharyngeal carcinoma (NPC)
- (2012) Christopher W. Dawson et al. SEMINARS IN CANCER BIOLOGY
- The Viral and Cellular MicroRNA Targetome in Lymphoblastoid Cell Lines
- (2012) Rebecca L. Skalsky et al. PLoS Pathogens
- MicroRNA-21: A novel therapeutic target in human cancer
- (2011) Xuan Pan et al. CANCER BIOLOGY & THERAPY
- Prognostic role of microRNA-21 in various carcinomas: a systematic review and meta-analysis
- (2011) Xiaonan Fu et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- Plasma epstein-barr virus DNA concentration and clearance rate as novel prognostic factors for metastatic nasopharyngeal carcinoma
- (2011) Cheng-Lung Hsu et al. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
- Up-regulation ofmiR-21Mediates Resistance to Trastuzumab Therapy for Breast Cancer
- (2011) Chang Gong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Expression and prognosis of FOXO3a and HIF-1α in nasopharyngeal carcinoma
- (2011) Zhu Shou et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Eight-Signature Classifier for Prediction of Nasopharyngeal Carcinoma Survival
- (2011) Hai-Yun Wang et al. JOURNAL OF CLINICAL ONCOLOGY
- LMP1 expression is positively associated with metastasis of nasopharyngeal carcinoma: evidence from a meta-analysis
- (2011) Yi Zhao et al. JOURNAL OF CLINICAL PATHOLOGY
- Epstein-Barr Virus Downregulates MicroRNA 203 through the Oncoprotein Latent Membrane Protein 1: a Contribution to Increased Tumor Incidence in Epithelial Cells
- (2011) H. Yu et al. JOURNAL OF VIROLOGY
- Epstein-Barr Virus Latent Membrane Protein 1 Induces Cancer Stem/Progenitor-Like Cells in Nasopharyngeal Epithelial Cell Lines
- (2011) S. Kondo et al. JOURNAL OF VIROLOGY
- Identification of plasma microRNA-21 as a biomarker for early detection and chemosensitivity of non-small cell lung cancer
- (2011) Juan Wei et al. Chinese Journal of Cancer
- The prevalence and prevention of nasopharyngeal carcinoma in China
- (2011) Su-Mei Cao et al. Chinese Journal of Cancer
- Programmed cell death 4 enhances chemosensitivity of ovarian cancer cells by activating death receptor pathway in vitro and in vivo
- (2010) Xia Zhang et al. CANCER SCIENCE
- Viral Latency and Its Regulation: Lessons from the γ-Herpesviruses
- (2010) Samuel H. Speck et al. Cell Host & Microbe
- MicroRNA-21 Is a Downstream Effector of AKT That Mediates Its Antiapoptotic Effects via Suppression of Fas Ligand
- (2010) Danish Sayed et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Foxo3a Regulates Apoptosis by Negatively Targeting miR-21
- (2010) Kun Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Epstein-Barr virus encoded latent membrane protein 1 regulates mTOR signaling pathway genes which predict poor prognosis of nasopharyngeal carcinoma
- (2010) Jing Chen et al. Journal of Translational Medicine
- A New Fork for Clinical Application: Targeting Forkhead Transcription Factors in Cancer
- (2009) J.-Y. Yang et al. CLINICAL CANCER RESEARCH
- Hyaluronan-CD44 Interaction with Protein Kinase Cϵ Promotes Oncogenic Signaling by the Stem Cell Marker Nanog and the Production of MicroRNA-21, Leading to Down-regulation of the Tumor Suppressor Protein PDCD4, Anti-apoptosis, and Chemotherapy Resistance in Breast Tumor Cells
- (2009) Lilly Y. W. Bourguignon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Epstein–Barr virus encoded LMP1 downregulates TCL1 oncogene through miR-29b
- (2009) E Anastasiadou et al. ONCOGENE
- Emerging roles of microRNAs as molecular switches in the integrated circuit of the cancer cell
- (2009) G. Sotiropoulou et al. RNA
- An Epstein-Barr virus–encoded microRNA targets PUMA to promote host cell survival
- (2008) Elizabeth Yee-Wai Choy et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Transcriptional patterns, biomarkers and pathways characterizing nasopharyngeal carcinoma of Southern China
- (2008) Weiyi Fang et al. Journal of Translational Medicine
- Molecular Basis of Cytotoxicity of Epstein-Barr Virus (EBV) Latent Membrane Protein 1 (LMP1) in EBV Latency III B Cells: LMP1 Induces Type II Ligand-Independent Autoactivation of CD95/Fas with Caspase 8-Mediated Apoptosis
- (2008) C. Le Clorennec et al. JOURNAL OF VIROLOGY
- Epstein-Barr Virus-Induced miR-155 Attenuates NF- B Signaling and Stabilizes Latent Virus Persistence
- (2008) F. Lu et al. JOURNAL OF VIROLOGY
- ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation
- (2008) Jer-Yen Yang et al. NATURE CELL BIOLOGY
- The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations
- (2008) A. Dubrovska et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epstein–Barr virus growth/latency III program alters cellular microRNA expression
- (2008) Jennifer E. Cameron et al. VIROLOGY
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