Downregulation of miR-200a Induces EMT Phenotypes and CSC-like Signatures through Targeting the β-catenin Pathway in Hepatic Oval Cells

ShRNA targeting Notch1 sensitizes breast cancer stem cell to paclitaxel

(2013) Jun Mao et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

WNT/β-catenin pathway activation in Myc immortalised cerebellar progenitor cells inhibits neuronal differentiation and generates tumours resembling medulloblastoma

(2012) H A Rogers et al.   BRITISH JOURNAL OF CANCER

Hepatic transforming growth factor beta gives rise to tumor-initiating cells and promotes liver cancer development

(2012) Kun Wu et al.   HEPATOLOGY

Novel therapeutic Strategies for Targeting Liver Cancer Stem Cells

(2012) Naoki Oishi et al.   International Journal of Biological Sciences

Hepatocellular carcinoma

(2012) Alejandro Forner et al.   LANCET

RETRACTED: Notch-1 induces epithelial–mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells

(2011) Bin Bao et al.   CANCER LETTERS

Hepatic oval cell lines generate hepatocellular carcinoma following transfection with HBx gene and treatment with aflatoxin B1 in vivo

(2011) Chang-Hai Li et al.   CANCER LETTERS

DCAMKL-1 Regulates Epithelial-Mesenchymal Transition in Human Pancreatic Cells through a miR-200a-Dependent Mechanism

(2011) S. M. Sureban et al.   CANCER RESEARCH

EMT and Stem Cell-Like Properties Associated with miR-205 and miR-200 Epigenetic Silencing Are Early Manifestations during Carcinogen-Induced Transformation of Human Lung Epithelial Cells

(2011) C. S. Tellez et al.   CANCER RESEARCH

MicroRNA-200a inhibits CD133/1+ ovarian cancer stem cells migration and invasion by targeting E-cadherin repressor ZEB2

(2011) Qiuhua Wu et al.   GYNECOLOGIC ONCOLOGY

The histone deacetylase 4/SP1/microrna-200a regulatory network contributes to aberrant histone acetylation in hepatocellular carcinoma

(2011) Ji-hang Yuan et al.   HEPATOLOGY

p53 regulates epithelial–mesenchymal transition through microRNAs targeting ZEB1 and ZEB2

(2011) Taewan Kim et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Differences in the Properties and Mirna Expression Profiles between Side Populations from Hepatic Cancer Cells and Normal Liver Cells

(2011) Wei-hui Liu et al.   PLoS One

Cancer stem cells and cancer therapy

(2011) Sara Soltanian et al.   TUMOR BIOLOGY

Disparate Cellular Basis of Improved Liver Repair in β-Catenin-Overexpressing Mice After Long-Term Exposure to 3,5-Diethoxycarbonyl-1,4-Dihydrocollidine

(2010) Michael D. Thompson et al.   AMERICAN JOURNAL OF PATHOLOGY

The role of the miR-200 family in epithelial-mesenchymal transition

(2010) Perry S. Mongroo et al.   CANCER BIOLOGY & THERAPY

Dynamic alteration of protein expression profiles during neoplastic transformation of rat hepatic oval-like cells

(2010) Xuefei Li et al.   CANCER SCIENCE

miR-130b Promotes CD133+ Liver Tumor-Initiating Cell Growth and Self-Renewal via Tumor Protein 53-Induced Nuclear Protein 1

(2010) Stephanie Ma et al.   Cell Stem Cell

 -catenin is constitutively active and increases STAT3 expression/activation in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma

(2010) M. Anand et al.   HAEMATOLOGICA

Bmi1promotes hepatic stem cell expansion and tumorigenicity in bothInk4a/Arf-dependent and -independent manners in Mice

(2010) Tetsuhiro Chiba et al.   HEPATOLOGY

miR-200a Regulates Epithelial-Mesenchymal to Stem-like Transition via ZEB2 and β-Catenin Signaling

(2010) Hongping Xia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of miR-200 Inhibition of Suz12 Leads to Polycomb-Mediated Repression Required for the Formation and Maintenance of Cancer Stem Cells

(2010) Dimitrios Iliopoulos et al.   MOLECULAR CELL

MicroRNA let-7b regulates neural stem cell proliferation and differentiation by targeting nuclear receptor TLX signaling

(2010) C. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening

(2009) Piyush B. Gupta et al.   CELL

Downregulation of miRNA-200c Links Breast Cancer Stem Cells with Normal Stem Cells

(2009) Yohei Shimono et al.   CELL

Inducible expression ofWntgenes during adult hepatic stem/progenitor cell response

(2009) Tohru Itoh et al.   FEBS LETTERS

Downregulated MicroRNA-200a in Meningiomas Promotes Tumor Growth by Reducing E-Cadherin and Activating the Wnt/ -Catenin Signaling Pathway

(2009) O. Saydam et al.   MOLECULAR AND CELLULAR BIOLOGY

The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

(2009) Ulrich Wellner et al.   NATURE CELL BIOLOGY

Wnt/ -Catenin Signaling Contributes to Activation of Normal and Tumorigenic Liver Progenitor Cells

(2008) W. Yang et al.   CANCER RESEARCH

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

EpCAM-Positive Hepatocellular Carcinoma Cells Are Tumor-Initiating Cells With Stem/Progenitor Cell Features

(2008) Taro Yamashita et al.   GASTROENTEROLOGY

Identification of local and circulating cancer stem cells in human liver cancer

(2008) Zhen Fan Yang et al.   HEPATOLOGY

Molecular mechanisms of hepatocellular carcinoma

(2008) Rajagopal N. Aravalli et al.   HEPATOLOGY

The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional RepressorsZEB1andZEB2

(2008) Manav Korpal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Liver Cancer Stem Cells

(2008) Stewart Sell et al.   JOURNAL OF CLINICAL ONCOLOGY

Stem cells in liver regeneration, fibrosis and cancer: the good, the bad and the ugly

(2008) MR Alison et al.   JOURNAL OF PATHOLOGY

Generation of Breast Cancer Stem Cells through Epithelial-Mesenchymal Transition

(2008) Anne-Pierre Morel et al.   PLoS One