Ubiquitin Ligase HUWE1 Regulates Axon Branching through the Wnt/β-Catenin Pathway in a Drosophila Model for Intellectual Disability

An autocrine Wnt5a-Ror signaling loop mediates sympathetic target innervation

(2013) Yun Kyoung Ryu et al.   DEVELOPMENTAL BIOLOGY

Wnt Signaling Is Required for Long-Term Memory Formation

(2013) Ying Tan et al.   Cell Reports

Copy-Number Gains of HUWE1 Due to Replication- and Recombination-Based Rearrangements

(2012) Guy Froyen et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Role for WNT/β-Catenin Signaling in the Neural Mechanisms of Behavior

(2012) Kimberly A. Maguschak et al.   Journal of Neuroimmune Pharmacology

Mutations in the chromatin modifier gene KANSL1 cause the 17q21.31 microdeletion syndrome

(2012) David A Koolen et al.   NATURE GENETICS

Genetic approaches in Drosophila for the study neurodevelopmental disorders

(2012) Zeynep Okray et al.   NEUROPHARMACOLOGY

Diagnostic Exome Sequencing in Persons with Severe Intellectual Disability

(2012) Joep de Ligt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Simple Neurite Tracer: open source software for reconstruction, visualization and analysis of neuronal processes

(2011) M. H. Longair et al.   BIOINFORMATICS

Wnt/PCP proteins regulate stereotyped axon branch extension in Drosophila

(2011) J. Ng   DEVELOPMENT

Common DISC1 Polymorphisms Disrupt Wnt/GSK3β Signaling and Brain Development

(2011) Karun K. Singh et al.   NEURON

Ubiquitin Ligase RNF146 Regulates Tankyrase and Axin to Promote Wnt Signaling

(2011) Marinella G. Callow et al.   PLoS One

Epigenetic Regulation of Learning and Memory by Drosophila EHMT/G9a

(2011) Jamie M. Kramer et al.   PLOS BIOLOGY

The various roles of ubiquitin in Wnt pathway regulation

(2010) Daniele V. F. Tauriello et al.   CELL CYCLE

Fruit flies and intellectual disability

(2010) Francois V. Bolduc et al.   FLY

TheDrosophilaLarval Neuromuscular Junction as a Model for Scaffold Complexes at Glutamatergic Synapses: Benefits and Limitations

(2010) Ulrich Thomas et al.   JOURNAL OF NEUROGENETICS

E3 Ligase Nedd4 Promotes Axon Branching by Downregulating PTEN

(2010) Jovana Drinjakovic et al.   NEURON

Genetically encoded dendritic marker sheds light on neuronal connectivity in Drosophila

(2010) L. J. J. Nicolai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Huwe1 ubiquitin ligase is essential to synchronize neuronal and glial differentiation in the developing cerebellum

(2010) D. D'Arca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The N-Myc-DLL3 Cascade Is Suppressed by the Ubiquitin Ligase Huwe1 to Inhibit Proliferation and Promote Neurogenesis in the Developing Brain

(2009) Xudong Zhao et al.   DEVELOPMENTAL CELL

Wnt signaling in development and disease

(2009) Jennifer L. Freese et al.   NEUROBIOLOGY OF DISEASE

Upregulation of three Drosophila homologs of human chromosome 21 genes alters synaptic function: Implications for Down syndrome

(2009) K. T. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Submicroscopic Duplications of the Hydroxysteroid Dehydrogenase HSD17B10 and the E3 Ubiquitin Ligase HUWE1 Are Associated with Mental Retardation

(2008) Guy Froyen et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Nuclear Dvl, c-Jun, β-catenin, and TCF form a complex leading to stabiLization of β-catenin–TCF interaction

(2008) Xiao-qing Gan et al.   JOURNAL OF CELL BIOLOGY