BRD4 Short Isoform Interacts with RRP1B, SIPA1 and Components of the LINC Complex at the Inner Face of the Nuclear Membrane

Identification of differential protein interactors of lamin A and progerin

(2014) Nard Kubben et al.   Nucleus

Mapping of protein- and chromatin-interactions at the nuclear lamina

(2014) Nard Kubben et al.   Nucleus

Phospho Switch Triggers Brd4 Chromatin Binding and Activator Recruitment for Gene-Specific Targeting

(2013) Shwu-Yuan Wu et al.   MOLECULAR CELL

The LINC-anchored actin cap connects the extracellular milieu to the nucleus for ultrafast mechanotransduction

(2013) Allison B. Chambliss et al.   Scientific Reports

BET bromodomain inhibition targets both c-Myc and IL7R in high-risk acute lymphoblastic leukemia

(2012) C. J. Ott et al.   BLOOD

Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family

(2012) Panagis Filippakopoulos et al.   CELL

Constitutive nuclear lamina-genome interactions are highly conserved and associated with A/T-rich sequence

(2012) W. Meuleman et al.   GENOME RESEARCH

MYC suppresses cancer metastasis by direct transcriptional silencing of αv and β3 integrin subunits

(2012) Hong Liu et al.   NATURE CELL BIOLOGY

Pathogenesis of NUT Midline Carcinoma

(2011) Christopher A. French   Annual Review of Pathology-Mechanisms of Disease

Application of Celluspots peptide arrays for the analysis of the binding specificity of epigenetic reading domains to modified histone tails

(2011) Ina Bock et al.   BMC BIOCHEMISTRY

Deletion of the Proline-Rich Region of the Murine Metastasis Susceptibility Gene Brd4 Promotes Epithelial-to-Mesenchymal Transition- and Stem Cell-Like Conversion

(2011) J. Alsarraj et al.   CANCER RESEARCH

BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

(2011) Jake E. Delmore et al.   CELL

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

(2011) Johannes Zuber et al.   NATURE

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

(2011) Mark A. Dawson et al.   NATURE

Targeting MYC dependence in cancer by inhibiting BET bromodomains

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Cancer Statistics, 2010

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Modeling metastasis biology and therapy in real time in the mouse lung

(2010) Arnulfo Mendoza et al.   JOURNAL OF CLINICAL INVESTIGATION

Comparison of Strong Cation Exchange and SDS-PAGE Fractionation for Analysis of Multiprotein Complexes

(2010) Sudipto Das et al.   JOURNAL OF PROTEOME RESEARCH

The Leukocyte Nuclear Envelope Proteome Varies with Cell Activation and Contains Novel Transmembrane Proteins That Affect Genome Architecture

(2010) Nadia Korfali et al.   MOLECULAR & CELLULAR PROTEOMICS

High-Resolution Whole-Genome Sequencing Reveals That Specific Chromatin Domains from Most Human Chromosomes Associate with Nucleoli

(2010) Silvana van Koningsbruggen et al.   MOLECULAR BIOLOGY OF THE CELL

RRP1B Targets PP1 to Mammalian Cell Nucleoli and Is Associated with Pre-60S Ribosomal Subunits

(2010) Delphine Chamousset et al.   MOLECULAR BIOLOGY OF THE CELL

Selective inhibition of BET bromodomains

(2010) Panagis Filippakopoulos et al.   NATURE

NUT Midline Carcinoma of the Parotid Gland With Mesenchymal Differentiation

(2009) Michael A. den Bakker et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Polymorphisms of the SIPA1 gene and sporadic breast cancer susceptibility

(2009) Szu-Min Hsieh et al.   BMC CANCER

The Metastasis Efficiency Modifier Ribosomal RNA Processing 1 Homolog B (RRP1B) Is a Chromatin-associated Factor

(2009) Nigel P. S. Crawford et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of E2F1-induced Apoptosis by the Nucleolar Protein RRP1B

(2009) Jason C. Paik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structures of the Dual Bromodomains of the P-TEFb-activating Protein Brd4 at Atomic Resolution

(2009) Friederike Vollmuth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ToppGene Suite for gene list enrichment analysis and candidate gene prioritization

(2009) J. Chen et al.   NUCLEIC ACIDS RESEARCH

Structural Basis and Binding Properties of the Second Bromodomain of Brd4 with Acetylated Histone Tails†‡

(2008) Ying Liu et al.   BIOCHEMISTRY

The Diasporin Pathway: a tumor progression-related transcriptional network that predicts breast cancer survival

(2008) Nigel P. S. Crawford et al.   CLINICAL & EXPERIMENTAL METASTASIS

Chemical probes for histone-modifying enzymes

(2008) Philip A Cole   Nature Chemical Biology

Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus

(2008) Ning Wang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Bromodomain 4 activation predicts breast cancer survival

(2008) N. P. S. Crawford et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA