Meclozine Facilitates Proliferation and Differentiation of Chondrocytes by Attenuating Abnormally Activated FGFR3 Signaling in Achondroplasia

Evaluation of the Therapeutic Potential of a CNP Analog in a Fgfr3 Mouse Model Recapitulating Achondroplasia

(2012) Florence Lorget et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A novel FGFR3-binding peptide inhibits FGFR3 signaling and reverses the lethal phenotype of mice mimicking human thanatophoric dysplasia

(2012) Min Jin et al.   HUMAN MOLECULAR GENETICS

A novel tyrosine kinase inhibitor restores chondrocyte differentiation and promotes bone growth in a gain-of-function Fgfr3 mouse model

(2011) Aurélie Jonquoy et al.   HUMAN MOLECULAR GENETICS

Meclizine is neuroprotective in models of Huntington's disease

(2010) V. M. Gohil et al.   HUMAN MOLECULAR GENETICS

NF449 Is a Novel Inhibitor of Fibroblast Growth Factor Receptor 3 (FGFR3) Signaling Active in Chondrocytes and Multiple Myeloma Cells

(2010) Pavel Krejci et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Systemic Administration of C-Type Natriuretic Peptide as a Novel Therapeutic Strategy for Skeletal Dysplasias

(2009) Akihiro Yasoda et al.   ENDOCRINOLOGY

Tannic acid facilitates expression of the polypyrimidine tract binding protein and alleviates deleterious inclusion of CHRNA1 exon P3A due to an hnRNP H-disrupting mutation in congenital myasthenic syndrome

(2009) Yang Bian et al.   HUMAN MOLECULAR GENETICS

The population-based prevalence of achondroplasia and thanatophoric dysplasia in selected regions of the US

(2008) D.K. Waller et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A