Genetic Background Can Result in a Marked or Minimal Effect of Gene Knockout (GPR55 and CB2 Receptor) in Experimental Autoimmune Encephalomyelitis Models of Multiple Sclerosis

GPR55, a G-Protein Coupled Receptor for Lysophosphatidylinositol, Plays a Role in Motor Coordination

(2013) Chia-Shan Wu et al.   PLoS One

Smoked cannabis for spasticity in multiple sclerosis: a randomized, placebo-controlled trial

(2012) J. Corey-Bloom et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Copy number variation in autoimmunity - importance hidden in complexity?

(2012) Lina M. Olsson et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Vitamin D receptor binding, chromatin states and association with multiple sclerosis

(2012) G. Disanto et al.   HUMAN MOLECULAR GENETICS

The CD27 and CD70 Costimulatory Pathway Inhibits Effector Function of T Helper 17 Cells and Attenuates Associated Autoimmunity

(2012) Jonathan M. Coquet et al.   IMMUNITY

MUltiple Sclerosis and Extract of Cannabis: results of the MUSEC trial

(2012) John Peter Zajicek et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Relapse and disability outcomes in patients with multiple sclerosis treated with fingolimod: subgroup analyses of the double-blind, randomised, placebo-controlled FREEDOMS study

(2012) Virginia Devonshire et al.   LANCET NEUROLOGY

A call for transparent reporting to optimize the predictive value of preclinical research

(2012) Story C. Landis et al.   NATURE

Cannabinoids ameliorate disease progression in a model of multiple sclerosis in mice, acting preferentially through CB1 receptor-mediated anti-inflammatory effects

(2012) Eva de Lago et al.   NEUROPHARMACOLOGY

Anti-Inflammatory Role of Cannabidiol and O-1602 in Cerulein-Induced Acute Pancreatitis in Mice

(2012) Kun Li et al.   PANCREAS

The biology that underpins the therapeutic potential of cannabis-based medicines for the control of spasticity in multiple sclerosis

(2012) David Baker et al.   Multiple Sclerosis and Related Disorders

Neutrophil protease inhibition reduces neuromyelitis optica-immunoglobulin G-induced damage in mouse brain

(2011) Samira Saadoun et al.   ANNALS OF NEUROLOGY

Cannabinoid CB1 receptors regulate neuronal TNF-α effects in experimental autoimmune encephalomyelitis

(2011) Silvia Rossi et al.   BRAIN BEHAVIOR AND IMMUNITY

Cannabidiol inhibits pathogenic T cells, decreases spinal microglial activation and ameliorates multiple sclerosis-like disease in C57BL/6 mice

(2011) Ewa Kozela et al.   BRITISH JOURNAL OF PHARMACOLOGY

GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils

(2011) Nariman A B Balenga et al.   CELL RESEARCH

Publication guidelines for refereeing and reporting on animal use in experimental autoimmune encephalomyelitis

(2011) David Baker et al.   JOURNAL OF NEUROIMMUNOLOGY

Targeting CB2 receptor as a neuroinflammatory modulator in experimental autoimmune encephalomyelitis

(2011) Zhi-Yin Lou et al.   MOLECULAR IMMUNOLOGY

Immunosuppression with FTY720 is insufficient to prevent secondary progressive neurodegeneration in experimental autoimmune encephalomyelitis

(2011) Sarah Al-Izki et al.   Multiple Sclerosis Journal

Critical appraisal of animal models of multiple sclerosis

(2011) David Baker et al.   Multiple Sclerosis Journal

Transient receptor potential vanilloid 1 channels modulate the synaptic effects of TNF-α and of IL-1β in experimental autoimmune encephalomyelitis

(2011) Gabriele Musumeci et al.   NEUROBIOLOGY OF DISEASE

Practical guide to the induction of relapsing progressive experimental autoimmune encephalomyelitis in the Biozzi ABH mouse

(2011) Sarah Al-Izki et al.   Multiple Sclerosis and Related Disorders

Requirement of cannabinoid CB1 receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections

(2010) Chia-Shan Wu et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Extensive infiltration of neutrophils in the acute phase of experimental autoimmune encephalomyelitis in C57BL/6 mice

(2010) Fenglan Wu et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Improving the translational hit of experimental treatments in multiple sclerosis

(2010) Hanna M Vesterinen et al.   Multiple Sclerosis Journal

T helper type 1 and 17 cells determine efficacy of interferon-β in multiple sclerosis and experimental encephalomyelitis

(2010) Robert C Axtell et al.   NATURE MEDICINE

International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2

(2010) R. G. Pertwee et al.   PHARMACOLOGICAL REVIEWS

Genetic polymorphisms among C57BL/6 mouse inbred strains

(2010) Esther Zurita et al.   TRANSGENIC RESEARCH

Cutting Edge: The Y Chromosome Controls the Age-Dependent Experimental Allergic Encephalomyelitis Sexual Dimorphism in SJL/J Mice

(2009) K. M. Spach et al.   JOURNAL OF IMMUNOLOGY

The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo

(2009) L. S. Whyte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The enigmatic pharmacology of GPR55

(2009) Ruth A. Ross   TRENDS IN PHARMACOLOGICAL SCIENCES

The CB2Cannabinoid Receptor Controls Myeloid Progenitor Trafficking

(2008) Javier Palazuelos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A role for sex chromosome complement in the female bias in autoimmune disease

(2008) Deborah L. Smith-Bouvier et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genetic deletion of Fatty Acid Amide Hydrolase results in improved long-term outcome in chronic autoimmune encephalitis

(2008) Michael Webb et al.   NEUROSCIENCE LETTERS

The putative cannabinoid receptor GPR55 plays a role in mechanical hyperalgesia associated with inflammatory and neuropathic pain

(2008) Penny C. Staton et al.   PAIN

Control of Spasticity in a Multiple Sclerosis Model is mediated by CB1, not CB2, Cannabinoid Receptors

(2007) G Pryce et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cannabinoid-mediated neuroprotection, not immunosuppression, may be more relevant to multiple sclerosis

(2007) J. Ludovic Croxford et al.   JOURNAL OF NEUROIMMUNOLOGY