SIRT1 Catalytic Activity Has Little Effect on Tumor Formation and Metastases in a Mouse Model of Breast Cancer

SIRT1 Suppresses the Epithelial-to-Mesenchymal Transition in Cancer Metastasis and Organ Fibrosis

(2013) Petra Simic et al.   Cell Reports

The caloric restriction paradigm: Implications for healthy human aging

(2012) Rozalyn M. Anderson et al.   AMERICAN JOURNAL OF HUMAN BIOLOGY

SIRT1 Pathway Dysregulation in the Smoke-Exposed Airway Epithelium and Lung Tumor Tissue

(2012) J. Beane et al.   CANCER RESEARCH

MiR-34a inhibits proliferation and migration of breast cancer through down-regulation of Bcl-2 and SIRT1

(2012) Laisheng Li et al.   CLINICAL AND EXPERIMENTAL MEDICINE

Loss of SIRT1 histone deacetylase expression associates with tumour progression in colorectal adenocarcinoma

(2012) Si-Hyong Jang et al.   JOURNAL OF CLINICAL PATHOLOGY

Expression of SIRT1 is associated with lymph node metastasis and poor prognosis in both operable triple-negative and non-triple-negative breast cancer

(2012) Minqing Wu et al.   MEDICAL ONCOLOGY

SIRT1 Is Essential for Oncogenic Signaling by Estrogen/Estrogen Receptor   in Breast Cancer

(2011) S. Elangovan et al.   CANCER RESEARCH

SirT1 catalytic activity is required for male fertility and metabolic homeostasis in mice

(2011) Erin L. Seifert et al.   FASEB JOURNAL

Negative regulation of stress-induced matrix metalloproteinase-9 by Sirt1 in skin tissue

(2010) Ji-Seon Lee et al.   EXPERIMENTAL DERMATOLOGY

Expression of DBC1 and SIRT1 is associated with poor prognosis for breast carcinoma

(2010) Ho Lee et al.   HUMAN PATHOLOGY

Sirtuin 1 Modulates Cellular Responses to Hypoxia by Deacetylating Hypoxia-Inducible Factor 1α

(2010) Ji-Hong Lim et al.   MOLECULAR CELL

Estrogen and Progesterone in Normal Mammary Gland Development and in Cancer

(2010) John Stingl   Hormones & Cancer

Inhibition of SIRT1 deacetylase suppresses estrogen receptor signaling

(2009) Y. Yao et al.   CARCINOGENESIS

A c-Myc–SIRT1 feedback loop regulates cell growth and transformation

(2009) Jian Yuan et al.   JOURNAL OF CELL BIOLOGY

SirT1-null mice develop tumors at normal rates but are poorly protected by resveratrol

(2009) G Boily et al.   ONCOGENE

Impaired DNA Damage Response, Genome Instability, and Tumorigenesis in SIRT1 Mutant Mice

(2008) Rui-Hong Wang et al.   CANCER CELL

SIRT1 Redistribution on Chromatin Promotes Genomic Stability but Alters Gene Expression during Aging

(2008) Philipp Oberdoerffer et al.   CELL

Linking sirtuins, IGF-I signaling, and starvation

(2008) Valter D. Longo   EXPERIMENTAL GERONTOLOGY

Interplay among BRCA1, SIRT1, and Survivin during BRCA1-Associated Tumorigenesis

(2008) Rui-Hong Wang et al.   MOLECULAR CELL

Negative regulation of the deacetylase SIRT1 by DBC1

(2008) Wenhui Zhao et al.   NATURE

SirT1 Regulates Energy Metabolism and Response to Caloric Restriction in Mice

(2008) Gino Boily et al.   PLoS One

The SIRT1 Deacetylase Suppresses Intestinal Tumorigenesis and Colon Cancer Growth

(2008) Ron Firestein et al.   PLoS One