Different Involvement of Promoter Methylation in the Expression of Organic Cation/Carnitine Transporter 2 (OCTN2) in Cancer Cell Lines

Melatonin-induced methylation of the ABCG2/BCRP promoter as a novel mechanism to overcome multidrug resistance in brain tumour stem cells

(2013) V Martín et al.   BRITISH JOURNAL OF CANCER

Human OCTN2 (SLC22A5) is down-regulated in virus- and nonvirus-mediated cancer

(2012) Mariafrancesca Scalise et al.   CELL BIOCHEMISTRY AND FUNCTION

Pretreatment of leukemic cells with low-dose decitabine markedly enhances the cytotoxicity of gemtuzumab ozogamicin

(2012) M Kurimoto et al.   LEUKEMIA

Polymorphisms in OCTN1 and OCTN2 transporters genes are associated with prolonged time to progression in unresectable gastrointestinal stromal tumours treated with imatinib therapy

(2012) Sabrina Angelini et al.   PHARMACOLOGICAL RESEARCH

The Effects of Promoter Methylation on Downregulation of DAZAP2 in Multiple Myeloma Cell Lines

(2012) Sai-Qun Luo et al.   PLoS One

Oxaliplatin Transport Mediated by Organic Cation/Carnitine Transporters OCTN1 and OCTN2 in Overexpressing Human Embryonic Kidney 293 Cells and Rat Dorsal Root Ganglion Neurons

(2011) N. N. Jong et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Promoter methylation and downregulation of SLC22A18 are associated with the development and progression of human glioma

(2011) Sheng-Hua Chu et al.   Journal of Translational Medicine

SLC5A8 Gene, A Transporter of Butyrate: A Gut Flora Metabolite, Is Frequently Methylated in African American Colon Adenomas

(2011) Hassan Brim et al.   PLoS One

DNA methylation is associated with downregulation of the organic cation transporter OCT1 (SLC22A1) in human hepatocellular carcinoma

(2011) Elke Schaeffeler et al.   Genome Medicine

ColonOCTN2Gene Expression Is Up-regulated by Peroxisome Proliferator-activated Receptor γ in Humans and Mice and Contributes to Local and Systemic Carnitine Homeostasis

(2010) Giuseppe D'Argenio et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Large-Scale, Consortium-Based Genomewide Association Study of Asthma

(2010) Miriam F. Moffatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genetic deficiency of carnitine/organic cation transporter 2 (slc22a5) is associated with altered tissue distribution of its substrate pyrilamine in mice

(2009) Sayaka Kato et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Carnitine/Organic Cation Transporter OCTN2 (Slc22a5) Is Responsible for Renal Secretion of Cephaloridine in Mice

(2009) T. Kano et al.   DRUG METABOLISM AND DISPOSITION

The Carnitine Transporter SLC22A5 Is Not a General Drug Transporter, but It Efficiently Translocates Mildronate

(2008) S. Grigat et al.   DRUG METABOLISM AND DISPOSITION

PPARα Mediates Transcriptional Upregulation of Novel Organic Cation Transporters-2 and -3 and Enzymes Involved in Hepatic Carnitine Synthesis

(2008) Alexander Koch et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Analysis of DNA Methylation and Histone Modification Profiles of Liver-Specific Transporters

(2008) S. Imai et al.   MOLECULAR PHARMACOLOGY