Salinomycin Activates AMP-Activated Protein Kinase-Dependent Autophagy in Cultured Osteoblastoma Cells: A Negative Regulator against Cell Apoptosis

Salinomycin induces cell death with autophagy through activation of endoplasmic reticulum stress in human cancer cells

(2013) Tianliang Li et al.   Autophagy

Salinomycin induces activation of autophagy, mitophagy and affects mitochondrial polarity: Differences between primary and cancer cells

(2013) Jaganmohan Reddy Jangamreddy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

TAK1 activates AMPK-dependent cell death pathway in hydrogen peroxide-treated cardiomyocytes, inhibited by heat shock protein-70

(2013) Zhiyu Chen et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Ursolic acid-induced AMP-activated protein kinase (AMPK) activation contributes to growth inhibition and apoptosis in human bladder cancer T24 cells

(2012) Qing-you Zheng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress

(2012) K Ketola et al.   BRITISH JOURNAL OF CANCER

Perifosine Induces Cell Apoptosis in Human Osteosarcoma Cells: New Implication for Osteosarcoma Therapy?

(2012) Chen Yao et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Perifosine sensitizes UVB-induced apoptosis in skin cells: New implication of skin cancer prevention?

(2012) Chao Ji et al.   CELLULAR SIGNALLING

AMP-Activated Protein Kinase: A Target for Drugs both Ancient and Modern

(2012) D. Grahame Hardie et al.   CHEMISTRY & BIOLOGY

AMP-activated protein kinase, stress responses and cardiovascular diseases

(2012) Shaobin Wang et al.   CLINICAL SCIENCE

Co-administration phenoxodiol with doxorubicin synergistically inhibit the activity of sphingosine kinase-1 (SphK1), a potential oncogene of osteosarcoma, to suppress osteosarcoma cell growth both in vivo and in vitro

(2012) Chen Yao et al.   Molecular Oncology

AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress

(2012) Sang-Min Jeon et al.   NATURE

Salinomycin Induces Autophagy in Colon and Breast Cancer Cells with Concomitant Generation of Reactive Oxygen Species

(2012) Berlinda Verdoodt et al.   PLoS One

AMPK and mTOR in Cellular Energy Homeostasis and Drug Targets

(2011) Ken Inoki et al.   Annual Review of Pharmacology and Toxicology

p62 at the Interface of Autophagy, Oxidative Stress Signaling, and Cancer

(2011) Ioannis P. Nezis et al.   ANTIOXIDANTS & REDOX SIGNALING

The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR

(2011) Dan Egan et al.   Autophagy

Salinomycin-induced apoptosis of human prostate cancer cells due to accumulated reactive oxygen species and mitochondrial membrane depolarization

(2011) Kwang-Youn Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Feedback on Fat: p62-mTORC1-Autophagy Connections

(2011) Jorge Moscat et al.   CELL

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

(2011) Maria M. Mihaylova et al.   NATURE CELL BIOLOGY

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells

(2011) Desheng Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Salinomycin overcomes ABC transporter-mediated multidrug and apoptosis resistance in human leukemia stem cell-like KG-1a cells

(2010) Dominik Fuchs et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The cancer stem cell selective inhibitor salinomycin is a p-glycoprotein inhibitor

(2010) Roberta Riccioni et al.   BLOOD CELLS MOLECULES AND DISEASES

Salinomycin sensitizes cancer cells to the effects of doxorubicin and etoposide treatment by increasing DNA damage and reducing p21 protein

(2010) Ju-Hwa Kim et al.   BRITISH JOURNAL OF PHARMACOLOGY

Physiological significance of selective degradation of p62 by autophagy

(2010) Masaaki Komatsu et al.   FEBS LETTERS

Activation of AMP-activated protein kinase is involved in vincristine-induced cell apoptosis in B16 melanoma cell

(2010) Min-Bin Chen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Autophagy Negatively Regulates Keratinocyte Inflammatory Responses via Scaffolding Protein p62/SQSTM1

(2010) H.-M. Lee et al.   JOURNAL OF IMMUNOLOGY

Hydrogen peroxide inhibits mTOR signaling by activation of AMPKα leading to apoptosis of neuronal cells

(2010) Long Chen et al.   LABORATORY INVESTIGATION

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

(2010) D. F. Egan et al.   SCIENCE

Inhibition of Autophagy by 3-MA Enhances the Effect of 5-FU-Induced Apoptosis in Colon Cancer Cells

(2009) Jie Li et al.   ANNALS OF SURGICAL ONCOLOGY

Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening

(2009) Piyush B. Gupta et al.   CELL

Autophagy Suppresses Tumorigenesis through Elimination of p62

(2009) Robin Mathew et al.   CELL

To Die or Not to Die: That is the Autophagic Question

(2008) Maria Maiuri et al.   CURRENT MOLECULAR MEDICINE

Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival

(2008) Patrick Narbonne et al.   NATURE