Determining Disease Intervention Strategies Using Spatially Resolved Simulations

In silico investigation of novel biological pathways: The role of CD200 in regulation of T cell priming in experimental autoimmune encephalomyelitis

(2013) Richard B. Greaves et al.   BIOSYSTEMS

Spartan: A Comprehensive Tool for Understanding Uncertainty in Simulations of Biological Systems

(2013) Kieran Alden et al.   PLoS Computational Biology

Engineering Simulations for Cancer Systems Biology

(2012) James Bown et al.   CURRENT DRUG TARGETS

Teplizumab for treatment of type 1 diabetes (Protégé study): 1-year results from a randomised, placebo-controlled trial

(2011) Nicole Sherry et al.   LANCET

Techniques for grounding agent-based simulations in the real domain: a case study in experimental autoimmune encephalomyelitis

(2011) Mark Read et al.   MATHEMATICAL AND COMPUTER MODELLING OF DYNAMICAL SYSTEMS

Four-year metabolic outcome of a randomised controlled CD3-antibody trial in recent-onset type 1 diabetic patients depends on their age and baseline residual beta cell mass

(2010) B. Keymeulen et al.   DIABETOLOGIA

CD8α+ dendritic cells prime TCR-peptide-reactive regulatory CD4+FOXP3− T cells

(2010) Trevor R. F. Smith et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Involvement of IFN-γ and perforin, but not Fas/FasL interactions in regulatory T cell-mediated suppression of experimental autoimmune encephalomyelitis

(2010) Tara Beeston et al.   JOURNAL OF NEUROIMMUNOLOGY

Agent-based models in translational systems biology

(2009) Gary An et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

Revival of CD8+ Treg–mediated suppression

(2008) Trevor R.F. Smith et al.   TRENDS IN IMMUNOLOGY