Sox2 Expression Is Regulated by a Negative Feedback Loop in Embryonic Stem Cells That Involves AKT Signaling and FoxO1
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Sox2 Expression Is Regulated by a Negative Feedback Loop in Embryonic Stem Cells That Involves AKT Signaling and FoxO1
Authors
Keywords
-
Journal
PLoS One
Volume 8, Issue 10, Pages e76345
Publisher
Public Library of Science (PLoS)
Online
2013-10-09
DOI
10.1371/journal.pone.0076345
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- miRNA-21 is developmentally regulated in mouse brain and is co-expressed with SOX2 in glioma
- (2012) Jelena Põlajeva et al. BMC CANCER
- Cyclin-Dependent Kinase Inhibitor p21 Controls Adult Neural Stem Cell Expansion by Regulating Sox2 Gene Expression
- (2012) M. Ángeles Marqués-Torrejón et al. Cell Stem Cell
- OCT4/SOX2-independentNanogautorepression modulates heterogeneousNanoggene expression in mouse ES cells
- (2012) Pablo Navarro et al. EMBO JOURNAL
- Determination of Protein Interactome of Transcription Factor Sox2 in Embryonic Stem Cells Engineered for Inducible Expression of Four Reprogramming Factors
- (2012) Zhiguang Gao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ERK1 and ERK2 regulate embryonic stem cell self-renewal through phosphorylation of Klf4
- (2012) Myoung Ok Kim et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Phosphorylation regulates human OCT4
- (2012) J. Brumbaugh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Zfp281 mediates Nanog autorepression through recruitment of the NuRD complex and inhibits somatic cell reprogramming
- (2012) M. Fidalgo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of embryonic stem cell self-renewal and pluripotency by leukaemia inhibitory factor
- (2011) Hiroyuki Hirai et al. BIOCHEMICAL JOURNAL
- Reprogramming Factor Stoichiometry Influences the Epigenetic State and Biological Properties of Induced Pluripotent Stem Cells
- (2011) Bryce W. Carey et al. Cell Stem Cell
- FOXO1 is an essential regulator of pluripotency in human embryonic stem cells
- (2011) Xin Zhang et al. NATURE CELL BIOLOGY
- Sox2 expression effects on direct reprogramming efficiency as determined by alternative somatic cell fate
- (2010) Shinpei Yamaguchi et al. Stem Cell Research
- Proteomic Analysis of Sox2-Associated Proteins During Early Stages of Mouse Embryonic Stem Cell Differentiation Identifies Sox21 as a Novel Regulator of Stem Cell Fate
- (2010) Sunil K. Mallanna et al. STEM CELLS
- Phosphorylation of Sox2 Cooperates in Reprogramming to Pluripotent Stem Cells
- (2010) Chul-Ho Jeong et al. STEM CELLS
- MicroRNA-145 Regulates OCT4, SOX2, and KLF4 and Represses Pluripotency in Human Embryonic Stem Cells
- (2009) Na Xu et al. CELL
- Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo
- (2009) J. Nichols et al. DEVELOPMENT
- Subcellular Localization of Glycogen Synthase Kinase 3 Controls Embryonic Stem Cell Self-Renewal
- (2009) M. Bechard et al. MOLECULAR AND CELLULAR BIOLOGY
- Increased AKT S473 phosphorylation after mTORC1 inhibition is rictor dependent and does not predict tumor cell response to PI3K/mTOR inhibition
- (2009) M. Breuleux et al. MOLECULAR CANCER THERAPEUTICS
- Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation
- (2009) E. P. Papapetrou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Effects of Akt signaling on nuclear reprogramming
- (2008) Toshinobu Nakamura et al. GENES TO CELLS
- Differential regulation of the Oct-3/4 gene in cell culture model systems that parallel different stages of mammalian development
- (2008) Sunil Kumar Mallanna et al. MOLECULAR REPRODUCTION AND DEVELOPMENT
- The ground state of embryonic stem cell self-renewal
- (2008) Qi-Long Ying et al. NATURE
- MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation
- (2008) Yvonne Tay et al. NATURE
- Small Increases in the Level of Sox2 Trigger the Differentiation of Mouse Embryonic Stem Cells
- (2008) Janel L. Kopp et al. STEM CELLS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started