GPR3 Stimulates Aβ Production via Interactions with APP and β-Arrestin2

2012 Alzheimer’s disease facts and figures

(2012)   Alzheimers & Dementia

Locus-specific mutation databases for neurodegenerative brain diseases

(2012) Marc Cruts et al.   HUMAN MUTATION

Loss of PAFAH1B2 Reduces Amyloid-  Generation by Promoting the Degradation of Amyloid Precursor Protein C-Terminal Fragments

(2012) R. M. Page et al.   JOURNAL OF NEUROSCIENCE

A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline

(2012) Thorlakur Jonsson et al.   NATURE

β-arrestin 2 regulates Aβ generation and γ-secretase activity in Alzheimer's disease

(2012) Amantha Thathiah et al.   NATURE MEDICINE

Rare Variants in APP, PSEN1 and PSEN2 Increase Risk for AD in Late-Onset Alzheimer's Disease Families

(2012) Carlos Cruchaga et al.   PLoS One

Resolving controversies on the path to Alzheimer's therapeutics

(2011) Dennis J Selkoe   NATURE MEDICINE

The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics

(2011) Eric Karran et al.   NATURE REVIEWS DRUG DISCOVERY

A GPCR/secretase complex regulates β- and γ-secretase specificity for Aβ production and contributes to AD pathogenesis

(2010) Lin Teng et al.   CELL RESEARCH

Targeting Aβ and tau in Alzheimer's disease, an early interim report

(2009) Todd E. Golde et al.   EXPERIMENTAL NEUROLOGY

The Orphan G Protein-Coupled Receptor 3 Modulates Amyloid-Beta Peptide Generation in Neurons

(2009) A. Thathiah et al.   SCIENCE

Activity-Induced Polo-Like Kinase 2 Is Required for Homeostatic Plasticity of Hippocampal Neurons during Epileptiform Activity

(2008) D. P. Seeburg et al.   JOURNAL OF NEUROSCIENCE