Identification of Highly Selective and Potent Histone Deacetylase 3 Inhibitors Using Click Chemistry-Based Combinatorial Fragment Assembly

HDAC3-selective inhibitor enhances extinction of cocaine-seeking behavior in a persistent manner

(2013) M. Malvaez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid Discovery of Highly Potent and Selective Inhibitors of Histone Deacetylase 8 Using Click Chemistry to Generate Candidate Libraries

(2012) Takayoshi Suzuki et al.   JOURNAL OF MEDICINAL CHEMISTRY

Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

(2012) N. M. Archin et al.   NATURE

Histone deacetylase (HDAC) inhibitors targeting HDAC3 and HDAC1 ameliorate polyglutamine-elicited phenotypes in model systems of Huntington's disease

(2012) Haiqun Jia et al.   NEUROBIOLOGY OF DISEASE

Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages

(2012) X. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New approaches in HIV eradication research

(2011) John Frater   CURRENT OPINION IN INFECTIOUS DISEASES

Novel histone deacetylase inhibitor NCH-51 activates latent HIV-1 gene expression

(2011) Ann Florence B. Victoriano et al.   FEBS LETTERS

Inhibitors of Histone Deacetylases

(2011) Kelly Huber et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelination

(2011) Ying Chen et al.   NATURE NEUROSCIENCE

An Unexpected Example of Protein-Templated Click Chemistry

(2010) Takayoshi Suzuki et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dissecting HDAC3-mediated tumor progression

(2010) John M. Mariadason   CANCER BIOLOGY & THERAPY

Hdac3 Is Essential for the Maintenance of Chromatin Structure and Genome Stability

(2010) Srividya Bhaskara et al.   CANCER CELL

Design and synthesis of novel hybrid benzamide–peptide histone deacetylase inhibitors

(2009) Fang Hu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Chemical Probes Identify a Role for Histone Deacetylase 3 in Friedreich's Ataxia Gene Silencing

(2009) Chunping Xu et al.   CHEMISTRY & BIOLOGY

Studies of Benzamide- and Thiol-Based Histone Deacetylase Inhibitors in Models of Oxidative-Stress-Induced Neuronal Death: Identification of Some HDAC3-Selective Inhibitors

(2009) Yufeng Chen et al.   ChemMedChem

Design, Synthesis, and Biological Activity of Boronic Acid-Based Histone Deacetylase Inhibitors

(2009) Nobuaki Suzuki et al.   JOURNAL OF MEDICINAL CHEMISTRY

High-Throughput Discovery ofMycobacterium tuberculosisProtein Tyrosine Phosphatase B (MptpB) Inhibitors Using Click Chemistry

(2009) Lay Pheng Tan et al.   ORGANIC LETTERS

Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3

(2008) Muthusamy Thangaraju et al.   BIOCHEMICAL JOURNAL

Histone deacetylases 1, 2 and 3 are highly expressed in prostate cancer and HDAC2 expression is associated with shorter PSA relapse time after radical prostatectomy

(2008) W Weichert et al.   BRITISH JOURNAL OF CANCER

Isoform-Selective Histone Deacetylase Inhibitors

(2008) Takayoshi Suzuki et al.   CURRENT PHARMACEUTICAL DESIGN

Histone Deacetylase Inhibitors: From Bench to Clinic

(2008) Marielle Paris et al.   JOURNAL OF MEDICINAL CHEMISTRY

In Situ “Click” Assembly of Small Molecule Matrix Metalloprotease Inhibitors Containing Zinc-Chelating Groups

(2008) Mingyu Hu et al.   ORGANIC LETTERS