Allosteric Coupling between the Intracellular Coupling Helix 4 and Regulatory Sites of the First Nucleotide-binding Domain of CFTR
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Title
Allosteric Coupling between the Intracellular Coupling Helix 4 and Regulatory Sites of the First Nucleotide-binding Domain of CFTR
Authors
Keywords
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Journal
PLoS One
Volume 8, Issue 9, Pages e74347
Publisher
Public Library of Science (PLoS)
Online
2013-09-19
DOI
10.1371/journal.pone.0074347
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- Human-mouse cystic fibrosis transmembrane conductance regulator (CFTR) chimeras identify regions that partially rescue CFTR- F508 processing and alter its gating defect
- (2011) Q. Dong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809
- (2011) F. Van Goor et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural consequences of ATP hydrolysis on the ABC transporter NBD dimer: Molecular dynamics studies of HlyB
- (2011) João M. Damas et al. PROTEIN SCIENCE
- Results of a phase IIa study of VX-809, an investigational CFTR corrector compound, in subjects with cystic fibrosis homozygous for theF508del-CFTRmutation
- (2011) J P Clancy et al. THORAX
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- Thermal unfolding studies show the disease causing F508del mutation in CFTR thermodynamically destabilizes nucleotide-binding domain 1
- (2010) Irina Protasevich et al. PROTEIN SCIENCE
- Integrated biophysical studies implicate partial unfolding of NBD1 of CFTR in the molecular pathogenesis of F508del cystic fibrosis
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- NMR evidence for differential phosphorylation-dependent interactions in WT and ΔF508 CFTR
- (2009) Voula Kanelis et al. EMBO JOURNAL
- The Conformational Transition Pathway of ATP Binding Cassette Transporter MsbA Revealed by Atomistic Simulations
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- State-dependent modulation of CFTR gating by pyrophosphate
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- Gating of the CFTR Cl−channel by ATP-driven nucleotide-binding domain dimerisation
- (2009) Tzyh-Chang Hwang et al. JOURNAL OF PHYSIOLOGY-LONDON
- Relationship between nucleotide binding and ion channel gating in cystic fibrosis transmembrane conductance regulator
- (2009) Andrei A. Aleksandrov et al. JOURNAL OF PHYSIOLOGY-LONDON
- Atomic model of human cystic fibrosis transmembrane conductance regulator: Membrane-spanning domains and coupling interfaces
- (2008) J.-P. Mornon et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Solubilizing Mutations Used to Crystallize One CFTR Domain Attenuate the Trafficking and Channel Defects Caused by the Major Cystic Fibrosis Mutation
- (2008) Luísa S. Pissarra et al. CHEMISTRY & BIOLOGY
- Multiple Membrane-Cytoplasmic Domain Contacts in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Mediate Regulation of Channel Gating
- (2008) Lihua He et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phenylalanine-508 mediates a cytoplasmic-membrane domain contact in the CFTR 3D structure crucial to assembly and channel function
- (2008) A. W. R. Serohijos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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