Activation of Protein Tyrosine Phosphatase Non-Receptor Type 2 by Spermidine Exerts Anti-Inflammatory Effects in Human THP-1 Monocytes and in a Mouse Model of Acute Colitis

Regulation of epithelial barrier function by the inflammatory bowel disease candidate gene, PTPN2

(2012) Declan F. McCole   Annals of the New York Academy of Sciences

Innate immune dysfunction in inflammatory bowel disease

(2012) M. Gersemann et al.   JOURNAL OF INTERNAL MEDICINE

Future Therapeutic Approaches for Inflammatory Bowel Diseases

(2011) Scott E. Plevy et al.   GASTROENTEROLOGY

New therapies for inflammatory bowel disease: from the bench to the bedside

(2011) Silvio Danese   GUT

Use of biological molecules in the treatment of inflammatory bowel disease

(2011) O. H. Nielsen et al.   JOURNAL OF INTERNAL MEDICINE

Genetics and pathogenesis of inflammatory bowel disease

(2011) Bernard Khor et al.   NATURE

Optimization of conventional therapy in patients with IBD

(2011) Kirstin M. Taylor et al.   Nature Reviews Gastroenterology & Hepatology

Inhibition of receptor tyrosine kinase signalling by small molecule agonist of T-cell protein tyrosine phosphatase

(2010) Elina Mattila et al.   BMC CANCER

Protein tyrosine phosphatase N2 regulates TNF -induced signalling and cytokine secretion in human intestinal epithelial cells

(2010) M. Scharl et al.   GUT

Protein Tyrosine Phosphatase non-Receptor Type 2 regulates IFN-γ-induced cytokine signaling in THP-1 monocytes

(2010) Michael Scharl et al.   INFLAMMATORY BOWEL DISEASES

Genome-wide association identifies multiple ulcerative colitis susceptibility loci

(2010) Dermot P B McGovern et al.   NATURE GENETICS

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

Protection of Epithelial Barrier Function by the Crohn's Disease Associated Gene Protein Tyrosine Phosphatase N2

(2009) Michael Scharl et al.   GASTROENTEROLOGY

T-cell protein tyrosine phosphatase is a key regulator in immune cell signaling: lessons from the knockout mouse model and implications in human disease

(2009) Karen M. Doody et al.   IMMUNOLOGICAL REVIEWS

Regulation of the Met Receptor-tyrosine Kinase by the Protein-tyrosine Phosphatase 1B and T-cell Phosphatase

(2008) Veena Sangwan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The protein tyrosine phosphatase TCPTP controls VEGFR2 signalling

(2008) E. Mattila et al.   JOURNAL OF CELL SCIENCE

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

(2008) Jeffrey C Barrett et al.   NATURE GENETICS