Silencing MED1 Sensitizes Breast Cancer Cells to Pure Anti-Estrogen Fulvestrant In Vitro and In Vivo

NFκB signaling is important for growth of antiestrogen resistant breast cancer cells

(2012) Christina W. Yde et al.   BREAST CANCER RESEARCH AND TREATMENT

Cross-talk between HER2 and MED1 Regulates Tamoxifen Resistance of Human Breast Cancer Cells

(2012) J. Cui et al.   CANCER RESEARCH

Med1 plays a critical role in the development of tamoxifen resistance

(2012) Arumugam Nagalingam et al.   CARCINOGENESIS

Single-vector inducible lentiviral RNAi system for oncology target validation

(2011) Dmitri Wiederschain et al.   CELL CYCLE

Bortezomib Enhances the Efficacy of Fulvestrant by Amplifying the Aggregation of the Estrogen Receptor, Which Leads to a Proapoptotic Unfolded Protein Response

(2011) Y. Ishii et al.   CLINICAL CANCER RESEARCH

Killing the second messenger: targeting loss of cell cycle control in endocrine-resistant breast cancer

(2011) C. A. Lange et al.   ENDOCRINE-RELATED CANCER

Autophagy and endocrine resistance in breast cancer

(2011) Katherine L Cook et al.   Expert Review of Anticancer Therapy

Arginine and Glutamate-rich 1 (ARGLU1) Interacts with Mediator Subunit 1 (MED1) and Is Required for Estrogen Receptor-mediated Gene Transcription and Breast Cancer Cell Growth

(2011) Dingxiao Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antiestrogens and Their Therapeutic Applications in Breast Cancer and Other Diseases

(2010) Simak Ali et al.   Annual Review of Medicine

Mechanisms of Endocrine Resistance in Breast Cancer

(2010) C. Kent Osborne et al.   Annual Review of Medicine

Cytokine Receptor CXCR4 Mediates Estrogen-Independent Tumorigenesis, Metastasis, and Resistance to Endocrine Therapy in Human Breast Cancer

(2010) Lyndsay V. Rhodes et al.   CANCER RESEARCH

Growth factor stimulation induces a distinct ER  cistrome underlying breast cancer endocrine resistance

(2010) M. Lupien et al.   GENES & DEVELOPMENT

Overcoming resistance to fulvestrant (ICI182,780) by Downregulating the c-ABL Proto-Oncogene in breast cancer

(2010) Huajun Zhao et al.   MOLECULAR CARCINOGENESIS

MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways

(2010) X Rao et al.   ONCOGENE

Key roles for MED1 LxxLL motifs in pubertal mammary gland development and luminal-cell differentiation

(2010) P. Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fulvestrant for systemic therapy of locally advanced or metastatic breast cancer in postmenopausal women: a systematic review

(2008) Jennifer Flemming et al.   BREAST CANCER RESEARCH AND TREATMENT

Activation of ErbB3, EGFR and Erk is essential for growth of human breast cancer cell lines with acquired resistance to fulvestrant

(2008) Thomas Frogne et al.   BREAST CANCER RESEARCH AND TREATMENT

PTEN-deficient cancers depend on PIK3CB

(2008) S. Wee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA