A Three-Marker FISH Panel Detects More Genetic Aberrations of AR, PTEN and TMPRSS2/ERG in Castration-Resistant or Metastatic Prostate Cancers than in Primary Prostate Tumors
Published 2013 View Full Article
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Title
A Three-Marker FISH Panel Detects More Genetic Aberrations of AR, PTEN and TMPRSS2/ERG in Castration-Resistant or Metastatic Prostate Cancers than in Primary Prostate Tumors
Authors
Keywords
Prostate cancer, Prostate gland, Fluorescent in situ hybridization, Metastatic tumors, Gene amplification, Lesions, Gene expression, Human genetics
Journal
PLoS One
Volume 8, Issue 9, Pages e74671
Publisher
Public Library of Science (PLoS)
Online
2013-10-01
DOI
10.1371/journal.pone.0074671
References
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Related references
Note: Only part of the references are listed.- A novel four-color fluorescence in situ hybridization assay for the detection of TMPRSS2 and ERG rearrangements in prostate cancer
- (2013) Xiaoyu Qu et al. Cancer Genetics
- The mutational landscape of lethal castration-resistant prostate cancer
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- Immunohistochemistry for ERG Expression as a Surrogate for TMPRSS2-ERG Fusion Detection in Prostatic Adenocarcinomas
- (2011) Alcides Chaux et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- Cell Autonomous Role of PTEN in Regulating Castration-Resistant Prostate Cancer Growth
- (2011) David J. Mulholland et al. CANCER CELL
- Reciprocal Feedback Regulation of PI3K and Androgen Receptor Signaling in PTEN-Deficient Prostate Cancer
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- Molecular characterisation of ERG, ETV1 and PTEN gene loci identifies patients at low and high risk of death from prostate cancer
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- The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression
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- Prevalence of TMPRSS2–ERG and SLC45A3–ERG gene fusions in a large prostatectomy cohort
- (2010) Raquel Esgueva et al. MODERN PATHOLOGY
- TMPRSS2-ERG Gene Fusion Is Not Associated with Outcome in Patients Treated by Prostatectomy
- (2009) Anuradha Gopalan et al. CANCER RESEARCH
- Comparative Analyses of Chromosome Alterations in Soft-Tissue Metastases within and across Patients with Castration-Resistant Prostate Cancer
- (2009) I. N. Holcomb et al. CANCER RESEARCH
- PTENgenomic deletion is associated with p-Akt and AR signalling in poorer outcome, hormone refractory prostate cancer
- (2009) Kanishka Sircar et al. JOURNAL OF PATHOLOGY
- Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis
- (2009) Jennifer C King et al. NATURE GENETICS
- Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate
- (2009) Brett S Carver et al. NATURE GENETICS
- Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer
- (2009) Wennuan Liu et al. NATURE MEDICINE
- ETS gene fusions in prostate cancer
- (2009) Jeremy P. Clark et al. Nature Reviews Urology
- Association of TMPRSS2-ERG gene fusion with clinical characteristics and outcomes: results from a population-based study of prostate cancer
- (2008) Liesel M FitzGerald et al. BMC CANCER
- Genomic Alterations Indicate Tumor Origin and Varied Metastatic Potential of Disseminated Cells from Prostate Cancer Patients
- (2008) I. N. Holcomb et al. CANCER RESEARCH
- Characterization of TMPRSS2-ETS Gene Aberrations in Androgen-Independent Metastatic Prostate Cancer
- (2008) R. Mehra et al. CANCER RESEARCH
- Absence of TMPRSS2:ERG fusions and PTEN losses in prostate cancer is associated with a favorable outcome
- (2008) Maisa Yoshimoto et al. MODERN PATHOLOGY
- Genetic profile identification in clinically localized prostate carcinoma
- (2008) Michele Gallucci et al. UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
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