Article
Public, Environmental & Occupational Health
Yuhan Gao, Wenqiao He, Jiaqi Fu, Yongzhi Li, Huan He, Qing Chen
Summary: This study investigated the transmission of murine Kobuvirus (MuKV) in murine rodents. The results showed that MuKV is predominantly transmitted through the fecal-oral route, with high infection rates in Rattus norvegicus and Rattus tanezumi. Phylogenetic analysis revealed a close genetic relationship between MuKV sequences from this study and those reported in other countries.
FRONTIERS IN PUBLIC HEALTH
(2022)
Review
Biochemistry & Molecular Biology
Nigel Paneth, Michael J. Joyner, Arturo Casadevall
Summary: RCTs are the most rigorous form of research in medicine, but their methodology limits their ability to provide timely and useful evidence in pandemic conditions. Therefore, medicine needs to consider evidence from non-traditional sources and use more flexible designs to address pandemics.
TRENDS IN MOLECULAR MEDICINE
(2022)
Article
Multidisciplinary Sciences
Pradeep Kumar, Chinmoyee Das, Arvind Kumar, Damodar Sahu, Sanjay K. Rai, Sheela Godbole, Elangovan Arumugam, P. V. M. Lakshmi, Shanta Dutta, H. Sanayaima Devi, Vishnu Vardhana Rao Mendu, Shashi Kant, Arvind Pandey, Dandu Chandra Sekhar Reddy, Sanjay Mehendale, Shobini Rajan
Summary: Based on UNAIDS recommended indicators, India's national AIDS response appears on track, but significant heterogeneity and expanding epidemic are observed across different states/UTs. Strengthening state/UTs-specific HIV prevention, testing, and treatment initiatives may help achieve the 2030 Sustainable Development Goals.
Article
Multidisciplinary Sciences
Theresa S. Ryckman, David W. Dowdy, Emily A. Kendall
Summary: The importance of finding people with undiagnosed tuberculosis (TB) lies in their future disease trajectories. The study shows that individuals with smear-positive subclinical TB have longer undiagnosed disease durations and contribute more to future transmission than symptomatic or smear-negative TB.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Mathematics, Applied
Salvador Merino, Juergen Doellner, Javier Martinez, Francisco Guzman, Rafael Guzman, Juan de Dios Lara
Summary: Mobile devices provide important data on spatial movements, which can be used to derive general mobility patterns for a population. This article presents a mathematical foundation using differential geometry and graph theory to harmonize mobile geolocation data and identify spatial behavior patterns. The approach includes using Computer Algebra Systems and a space-time model to describe contagion patterns. It also develops algorithms for finding patient zero and identifying potentially contagious individuals. This method can be used by information systems to analyze complex population movements and identify critical areas, time segments, and vulnerable individuals with respect to contact events.
Article
Multidisciplinary Sciences
Yeongseon Park, Michael A. Martin, Katia Koelle
Summary: The authors propose an inference approach based on sequence data, which is suitable for model fitting during the early expansion of a viral lineage. It accurately estimates epidemiological parameters and is applied to SARS-CoV-2 sequence data from France, estimating a basic reproduction number of approximately 2.3-2.7 under a multiple-introduction epidemiological model. This study suggests that inference approaches relying on simple population genetic summary statistics can provide informative insights into epidemiological parameters and the dynamics of infectious diseases during the early expansion of a viral lineage.
NATURE COMMUNICATIONS
(2023)
Letter
Immunology
Hongling Jia, Tong Sha, Shilei Zhao, Wenzhe Su, Peiwen Liu, Ruonan Zhen, Peihan Li, Lijuan Zhou, Yang Xu, Yunjing Wen, Lianjiang Chi, Biao Di, Peng Li, Hua Chen, Pengzhe Qin
Summary: From June 7th to 11th, 2023, eight cases of Mpox were identified in Guangzhou, China. The cases had no international travel history and no connections with each other. The possible origin of the virus is likely from Japan, although this remains uncertain due to limited genomic sequences and sampling bias. The local transmission of Mpox in Guangzhou may have been ongoing for some time, with more than 300 possible infected cases inferred based on the early stage outbreak in other countries. Swift and efficient control measures are necessary to mitigate the risk of a potential epidemic.
EMERGING MICROBES & INFECTIONS
(2023)
Article
Veterinary Sciences
Yan Li, Jinjin Wang, Longfei Chen, Qun Wang, Meng Zhou, Hui Zhao, Zengna Chi, Yixin Wang, Shuang Chang, Peng Zhao
Summary: This study found that vertical transmission of CIAV from a SPF layer breeder flock to embryos is an important pathway for exogenous virus contamination in live vaccine production.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Review
Neurosciences
Paulina Gonzalez-Latapi, Connie Marras
Summary: There is a growing interest in understanding the role of the immune system and inflammatory response in the development of Parkinson's disease. Epidemiological evidence suggests that Parkinson's disease may be immune-mediated, with associations observed between inflammatory bowel disease and an increased risk of Parkinson's. Medications that suppress the immune system may decrease the risk of Parkinson's, and there are shared genetic variants between Parkinson's and autoimmune conditions. Further research is needed to fully understand the relationship between the immune system and Parkinson's disease.
JOURNAL OF PARKINSONS DISEASE
(2022)
Review
Biochemistry & Molecular Biology
Roberto Lucchini, Kim Tieu
Summary: Manganese exposure has shifted from acute to chronic, resulting in investigations of the long-term impact on Parkinson's disease and parkinsonism. Experimental research has explored the pathogenic mechanisms and genetic susceptibility associated with manganese. This review aims to link epidemiological data with potential mechanistic interpretations.
Article
Multidisciplinary Sciences
Gianmario Rinaldi, Prathyush P. Menon, Antonella Ferrara, W. David Strain, Christopher Edwards
Summary: This study explores the use of an epidemiological compartmental model to devise a periodic adaptive suppression/intervention policy to alleviate the pressure on the UK's National Health Service (NHS) caused by the COVID-19 pandemic. The results show that the proposed policy has the potential to reduce hospitalization by an average of 58% per month and remains effective in various future scenarios.
SCIENTIFIC REPORTS
(2022)
Article
Oncology
Loris De Cecco, Marina Bagnoli, Paolo Chiodini, Sandro Pignata, Delia Mezzanzanica
Summary: MiROvaR, a miRNA-based classifier, has been validated for its ability to predict early relapse risk in epithelial ovarian cancer patients through analysis of a new independent cohort, demonstrating its prognostic value and reliability.
Article
Psychology, Multidisciplinary
Jose Ramon Lete-Lasa, Rafael Martin-Acero, Javier Rico-Diaz, Joaquin Gomez-Varela, Dan Rio-Rodriguez
Summary: This study describes the methodological process for creating a tool to identify potential COVID-19 contagion situations in sports and physical education, and presents the results of implementing this tool in the sports system of Galicia, Spain. The aim is to reduce residual risk through an exhaustive analysis, risk detection, and contingency measures, with technicians changing their perceptions of coronavirus transmission in sports. Specific attention is given to the challenges faced by athletes under 18 returning to sports participation during the pandemic.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Immunology
Ralf Krumkamp, Cassandra Aldrich, Oumou Maiga-Ascofare, Joyce Mbwana, Njari Rakotozandrindrainy, Steffen Borrmann, Simone M. Caccio, Raphael Rakotozandrindrainy, Ayola Akim Adegnika, John P. A. Lusingu, John Amuasi, Juergen May, Daniel Eibach
Summary: Cryptosporidiosis in rural sub-Saharan Africa is characterized by infection clusters among human contacts, to which zoonotic transmission appears to contribute only marginally.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Agriculture, Dairy & Animal Science
Andrew C. Gallup, Anja B. Schild, Markus A. Uehlein, Thomas Bugnyar, Jorg J. M. Massen
Summary: This study found no evidence for contagious yawning among juvenile common ravens. However, considering the limitations of observational methods, further experimental research should be conducted to support these findings.
Article
Biochemistry & Molecular Biology
Sandra Reuter, M. Estee Toeroek, Matthew T. G. Holden, Rosy Reynolds, Kathy E. Raven, Beth Blane, Tjibbe Donker, Stephen D. Bentley, David M. Aanensen, Hajo Grundmann, Edward J. Feil, Brian G. Spratt, Julian Parkhill, Sharon J. Peacock
Article
Infectious Diseases
Colin J. Worby, Sandra S. Chaves, Jacco Wallinga, Marc Lipsitch, Lyn Finelli, Edward Goldstein
Article
Medicine, General & Internal
Johannes A. Bogaards, Jacco Wallinga, Ruud H. Brakenhoff, Chris J. L. M. Meijer, Johannes Berkhof
BMJ-BRITISH MEDICAL JOURNAL
(2015)
Article
Medicine, General & Internal
Johannes A. Bogaards, Jacco Wallinga, Ruud H. Brakenhoff, Chris J. L. M. Meijer, Johannes Berkhof
BMJ-BRITISH MEDICAL JOURNAL
(2015)
Article
Infectious Diseases
M. Gabriela M. Gomes, Mauricio L. Barreto, Philippe Glaziou, Graham F. Medley, Laura C. Rodrigues, Jacco Wallinga, S. Bertel Squire
BMC INFECTIOUS DISEASES
(2016)
Article
Infectious Diseases
X. Yan, L. M. Schouls, G. N. Pluister, X. Tao, X. Yu, J. Yin, Y. Song, S. Hu, F. Luo, W. Hu, L. He, F. Meng, T. Donker, E. Tsompanidou, J. M. van Dijl, J. Zhang, H. Grundmann
CLINICAL MICROBIOLOGY AND INFECTION
(2016)
Article
Public, Environmental & Occupational Health
Carline van den Dool, Anja Haenen, Tjalling Leenstra, Jacco Wallinga
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2016)
Article
Infectious Diseases
Scott A. McDonald, Liselotte van Asten, Wim van der Hoek, Ge A. Donker, Jacco Wallinga
INFLUENZA AND OTHER RESPIRATORY VIRUSES
(2016)
Article
Public, Environmental & Occupational Health
T. Donker, T. Bosch, R. J. F. Ypma, A. P. J. Haenen, W. M. van Ballegooijen, M. E. O. C. Heck, L. M. Schouls, J. Wallinga, H. Grundmann
JOURNAL OF HOSPITAL INFECTION
(2016)
Article
Infectious Diseases
Maarten van Wijhe, Scott A. McDonald, Hester E. de Melker, Maarten J. Postma, Jacco Wallinga
LANCET INFECTIOUS DISEASES
(2016)
Article
Biology
Evelot Duijzer, Willem van Jaarsveld, Jacco Wallinga, Rommert Dekker
MATHEMATICAL BIOSCIENCES
(2016)
Article
Infectious Diseases
Maria Xiridou, Anna Lugner, Henry J. C. de Vries, Jan E. A. M. van Bergen, Hannelore M. Gotz, Birgit H. B. van Benthem, Jacco Wallinga, Marianne A. B. van der Sande
SEXUALLY TRANSMITTED DISEASES
(2016)
Article
Genetics & Heredity
Hsiao-Han Chang, Janina Dordel, Tjibbe Donker, Colin J. Worby, Edward J. Feil, William P. Hanage, Stephen D. Bentley, Susan S. Huang, Marc Lipsitch
Article
Multidisciplinary Sciences
Alies van Lier, Scott A. McDonald, Martijn Bouwknegt, Mirjam E. Kretzschmar, Arie H. Havelaar, Marie-Josee J. Mangen, Jacco Wallinga, Hester E. de Melker