The Pathological Phenotypes of Human TDP-43 Transgenic Mouse Models Are Independent of Downregulation of Mouse Tdp-43
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Title
The Pathological Phenotypes of Human TDP-43 Transgenic Mouse Models Are Independent of Downregulation of Mouse Tdp-43
Authors
Keywords
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Journal
PLoS One
Volume 8, Issue 7, Pages e69864
Publisher
Public Library of Science (PLoS)
Online
2013-07-27
DOI
10.1371/journal.pone.0069864
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Note: Only part of the references are listed.- Neuronal sensitivity to TDP-43 overexpression is dependent on timing of induction
- (2012) Ashley Cannon et al. ACTA NEUROPATHOLOGICA
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- (2012) William Tsao et al. BRAIN RESEARCH
- Unraveling the Complexity of Amyotrophic Lateral Sclerosis: Recent Advances from the Transgenic Mutant SOD1 Mice
- (2012) M. Peviani et al. CNS & Neurological Disorders-Drug Targets
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- (2012) S. E. Avendano-Vazquez et al. GENES & DEVELOPMENT
- Targeted Depletion of TDP-43 Expression in the Spinal Cord Motor Neurons Leads to the Development of Amyotrophic Lateral Sclerosis-like Phenotypes in Mice
- (2012) Lien-Szu Wu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Misregulation of human sortilin splicing leads to the generation of a nonfunctional progranulin receptor
- (2012) M. Prudencio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sortilin: a receptor to regulate neuronal viability and function
- (2012) Anders Nykjaer et al. TRENDS IN NEUROSCIENCES
- Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments
- (2011) Vivek Swarup et al. BRAIN
- Transgenic Mice as a Model for Alzheimers Disease
- (2011) Christina Unger Lithner et al. Current Alzheimer Research
- Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice
- (2011) Lionel M. Igaz et al. JOURNAL OF CLINICAL INVESTIGATION
- Expression of mutant TDP-43 induces neuronal dysfunction in transgenic mice
- (2011) Ya-Fei Xu et al. Molecular Neurodegeneration
- TDP-43 regulates its mRNA levels through a negative feedback loop
- (2010) Youhna M Ayala et al. EMBO JOURNAL
- Identification of Neuronal RNA Targets of TDP-43-containing Ribonucleoprotein Complexes
- (2010) Chantelle F. Sephton et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Elevated expression of TDP-43 in the forebrain of mice is sufficient to cause neurological and pathological phenotypes mimicking FTLD-U
- (2010) Kuen-Jer Tsai et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Wild-Type Human TDP-43 Expression Causes TDP-43 Phosphorylation, Mitochondrial Aggregation, Motor Deficits, and Early Mortality in Transgenic Mice
- (2010) Y.-F. Xu et al. JOURNAL OF NEUROSCIENCE
- Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism
- (2010) P.-M. Chiang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice
- (2010) X. Shan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration
- (2010) Hans Wils et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The multiple roles of TDP-43 in pre-mRNA processing and gene expression regulation
- (2010) Emanuele Buratti et al. RNA Biology
- Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6
- (2009) Fabienne C Fiesel et al. EMBO JOURNAL
- TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration
- (2009) I. Wegorzewska et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TDP-43mutation in familial amyotrophic lateral sclerosis
- (2008) Akio Yokoseki et al. ANNALS OF NEUROLOGY
- TDP-43A315T mutation in familial motor neuron disease
- (2008) Michael A. Gitcho et al. ANNALS OF NEUROLOGY
- PSD-95 promotes synaptogenesis and multiinnervated spine formation through nitric oxide signaling
- (2008) Irina Nikonenko et al. JOURNAL OF CELL BIOLOGY
- TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis
- (2008) Edor Kabashi et al. NATURE GENETICS
- Animal models of Alzheimer's disease and frontotemporal dementia
- (2008) Jürgen Götz et al. NATURE REVIEWS NEUROSCIENCE
- TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis
- (2008) J. Sreedharan et al. SCIENCE
- Novel Mutations in TARDBP (TDP-43) in Patients with Familial Amyotrophic Lateral Sclerosis
- (2008) Nicola J. Rutherford et al. PLoS Genetics
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