Pneumococcal Polysaccharide Abrogates Conjugate-Induced Germinal Center Reaction and Depletes Antibody Secreting Cell Pool, Causing Hyporesponsiveness
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Title
Pneumococcal Polysaccharide Abrogates Conjugate-Induced Germinal Center Reaction and Depletes Antibody Secreting Cell Pool, Causing Hyporesponsiveness
Authors
Keywords
Spleen, Enzyme-linked immunoassays, Conjugate vaccines, Plasma cells, Mouse models, Booster doses, Neonates, B cells
Journal
PLoS One
Volume 8, Issue 9, Pages e72588
Publisher
Public Library of Science (PLoS)
Online
2013-09-13
DOI
10.1371/journal.pone.0072588
References
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