LC-MS/MS Confirms That COX-1 Drives Vascular Prostacyclin Whilst Gene Expression Pattern Reveals Non-Vascular Sites of COX-2 Expression

Historical Lessons in Translational Medicine

(2013) Desmond J. Fitzgerald et al.   CIRCULATION RESEARCH

COX-2, the dominant source of prostacyclin

(2013) E. Ricciotti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyclooxygenase-2–Derived Prostacyclin Regulates Arterial Thrombus Formation by Suppressing Tissue Factor in a Sirtuin-1–Dependent-Manner

(2012) Silvia S. Barbieri et al.   CIRCULATION

Disruption of the 5-lipoxygenase pathway attenuates atherogenesis consequent to COX-2 deletion in mice

(2012) Z. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyclooxygenase-1, not cyclooxygenase-2, is responsible for physiological production of prostacyclin in the cardiovascular system

(2012) N. S. Kirkby et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disturbed Blood Flow Induces RelA Expression via c-Jun N-Terminal Kinase 1

(2011) Simon Cuhlmann et al.   CIRCULATION RESEARCH

Involvement of cyclo-oxygenase-1-mediated prostacyclin synthesis in the vasoconstrictor activity evoked by ACh in mouse arteries

(2011) Bin Liu et al.   EXPERIMENTAL PHYSIOLOGY

Cardiovascular Risk with Non-Steroidal Anti-Inflammatory Drugs: Systematic Review of Population-Based Controlled Observational Studies

(2011) Patricia McGettigan et al.   PLOS MEDICINE

Preserved heart function and maintained response to cardiac stresses in a genetic model of cardiomyocyte-targeted deficiency of cyclooxygenase-2

(2010) Kyriakos N. Papanicolaou et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cox-2 gene expression in chemically induced skin papillomas cannot predict subsequent tumor fate

(2010) Tomo-o Ishikawa et al.   Molecular Oncology

Cardiomyocyte cyclooxygenase-2 influences cardiac rhythm and function

(2009) D. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Feedback regulation of cyclooxygenase-2 transcription ex vivo and in vivo

(2008) Tomo-o Ishikawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cyclooxygenase-2-Linked Attenuation of Hypoxia-Induced Pulmonary Hypertension and Intravascular Thrombosis

(2008) M.-C. Cathcart et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS