mGluR5 Ablation in Cortical Glutamatergic Neurons Increases Novelty-Induced Locomotion

Enhanced Intrinsic Excitability in Basket Cells Maintains Excitatory-Inhibitory Balance in Hippocampal Circuits

(2013) Emilie Campanac et al.   NEURON

GPR55, a G-Protein Coupled Receptor for Lysophosphatidylinositol, Plays a Role in Motor Coordination

(2013) Chia-Shan Wu et al.   PLoS One

Glutamate-Dependent Neuroglial Calcium Signaling Differs Between Young and Adult Brain

(2013) W. Sun et al.   SCIENCE

The Pathophysiology of Fragile X (and What It Teaches Us about Synapses)

(2012) Asha L. Bhakar et al.   Annual Review of Neuroscience

Prenatal Nicotine Exposure Mouse Model Showing Hyperactivity, Reduced Cingulate Cortex Volume, Reduced Dopamine Turnover, and Responsiveness to Oral Methylphenidate Treatment

(2012) J. Zhu et al.   JOURNAL OF NEUROSCIENCE

De Novo Gene Disruptions in Children on the Autistic Spectrum

(2012) Ivan Iossifov et al.   NEURON

Metabotropic glutamate receptor 5 in the pathology and treatment of schizophrenia

(2012) Natalie Matosin et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

High-Throughput Sequencing of mGluR Signaling Pathway Genes Reveals Enrichment of Rare Variants in Autism

(2012) Raymond J. Kelleher III et al.   PLoS One

Characterization of Highper, an ENU-induced mouse mutant with abnormal psychostimulant and stress responses

(2012) Amy F. Eisener-Dorman et al.   PSYCHOPHARMACOLOGY

Attention-Deficit/Hyperactivity Disorder Genomics: Update for Clinicians

(2012) Josephine Elia et al.   Current Psychiatry Reports

Modifying behavioral phenotypes in Fmr1KO mice: genetic background differences reveal autistic-like responses

(2011) Corinne M. Spencer et al.   Autism Research

De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia

(2011) G Kirov et al.   MOLECULAR PSYCHIATRY

Epigenetic Modification of the FMR1 Gene in Fragile X Syndrome Is Associated with Differential Response to the mGluR5 Antagonist AFQ056

(2011) S. Jacquemont et al.   Science Translational Medicine

Toward Fulfilling the Promise of Molecular Medicine in Fragile X Syndrome

(2010) Dilja D. Krueger et al.   Annual Review of Medicine

Metabotropic Glutamate Receptors: Physiology, Pharmacology, and Disease

(2010) Colleen M. Niswender et al.   Annual Review of Pharmacology and Toxicology

Interneuron subtype specific activation of mGluR1/5 during epileptiform activity in hippocampus

(2010) Nathalie T Sanon et al.   EPILEPSIA

mGluR5 in Cortical Excitatory Neurons Exerts Both Cell-Autonomous and -Nonautonomous Influences on Cortical Somatosensory Circuit Formation

(2010) C. J. Ballester-Rosado et al.   JOURNAL OF NEUROSCIENCE

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

(2010) Hsiao-Tuan Chao et al.   NATURE

Group 1 mGluR-Dependent Synaptic Long-Term Depression: Mechanisms and Implications for Circuitry and Disease

(2010) Christian Lüscher et al.   NEURON

Operant Sensation Seeking Requires Metabotropic Glutamate Receptor 5 (mGluR5)

(2010) Christopher M. Olsen et al.   PLoS One

Roles of mGluR5 in synaptic function and plasticity of the mouse thalamocortical pathway

(2009) Wei-Chi She et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Cocaine-mediated synaptic potentiation is absent in VTA neurons from mGlu5-deficient mice

(2009) Michael K. Bird et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Differential Metabotropic Glutamate Receptor Expression and Modulation in Two Neocortical Inhibitory Networks

(2009) Qian-Quan Sun et al.   JOURNAL OF NEUROPHYSIOLOGY

mGluR5 Has a Critical Role in Inhibitory Learning

(2009) J. Xu et al.   JOURNAL OF NEUROSCIENCE

Activity-Dependent Regulation of Synapses by Retrograde Messengers

(2009) Wade G. Regehr et al.   NEURON

Endocannabinoid-Mediated Control of Synaptic Transmission

(2009) Masanobu Kano et al.   PHYSIOLOGICAL REVIEWS

Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety

(2009) Alexia Thomas et al.   PSYCHOPHARMACOLOGY

Clozapine reverses schizophrenia-related behaviours in the metabotropic glutamate receptor 5 knockout mouse: association with N-methyl-d-aspartic acid receptor up-regulation

(2008) Laura Gray et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Role for metabotropic glutamate receptor 5 (mGluR5) in the pathogenesis of fragile X syndrome

(2008) Gül Dölen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania

(2008) G Shaltiel et al.   MOLECULAR PSYCHIATRY

Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia

(2008) P. Jeffrey Conn et al.   TRENDS IN PHARMACOLOGICAL SCIENCES