Stimulation of Osteoclast Formation by RANKL Requires Interferon Regulatory Factor-4 and Is Inhibited by Simvastatin in a Mouse Model of Bone Loss
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Stimulation of Osteoclast Formation by RANKL Requires Interferon Regulatory Factor-4 and Is Inhibited by Simvastatin in a Mouse Model of Bone Loss
Authors
Keywords
Osteoclasts, Mouse models, Transcription factors, Small interfering RNAs, Cell differentiation, Gene expression, Bone density, Promoter regions
Journal
PLoS One
Volume 8, Issue 9, Pages e72033
Publisher
Public Library of Science (PLoS)
Online
2013-09-12
DOI
10.1371/journal.pone.0072033
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Interaction of Protein Phosphatase 1δ with Nucleophosmin in Human Osteoblastic Cells
- (2011) Tatsuji Haneji et al. ACTA HISTOCHEMICA ET CYTOCHEMICA
- Epigenetic regulation of osteoclast differentiation
- (2011) Tetsuro Yasui et al. Annals of the New York Academy of Sciences
- Epigenetic regulation of osteoclast differentiation: Possible involvement of Jmjd3 in the histone demethylation of Nfatc1
- (2011) Tetsuro Yasui et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Simvastatin Inhibits IFN Regulatory Factor 4 Expression and Th17 Cell Differentiation in CD4+ T Cells Derived from Patients with Multiple Sclerosis
- (2011) X. Zhang et al. JOURNAL OF IMMUNOLOGY
- Weighing the Benefits of High-Dose Simvastatin against the Risk of Myopathy
- (2011) Amy Egan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Neuromedin U is necessary for normal gastrointestinal motility and is regulated by serotonin
- (2010) Yoshiki Nakashima et al. Annals of the New York Academy of Sciences
- Double stranded RNA-dependent protein kinase is involved in osteoclast differentiation of RAW264.7 cells in vitro
- (2010) Junpei Teramachi et al. EXPERIMENTAL CELL RESEARCH
- The Rac1 exchange factor Dock5 is essential for bone resorption by osteoclasts
- (2010) Virginie Vives et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Macrophage inflammatory protein-1α induces osteoclast formation by activation of the MEK/ERK/c-Fos pathway and inhibition of the p38MAPK/IRF-3/IFN-β pathway
- (2010) Masanobu Tsubaki et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice
- (2010) Partha S. Biswas et al. JOURNAL OF CLINICAL INVESTIGATION
- Retinoic Acid Increases Proliferation of Human Osteoclast Progenitors and Inhibits RANKL-Stimulated Osteoclast Differentiation by Suppressing RANK
- (2010) Lijuan Hu et al. PLoS One
- Evaluation of Pharmaceuticals With a Novel 50-Hour Animal Model of Bone Loss*
- (2009) Yoshiya Tomimori et al. JOURNAL OF BONE AND MINERAL RESEARCH
- GM-CSF Regulates Fusion of Mononuclear Osteoclasts into Bone-Resorbing Osteoclasts by Activating the Ras/ERK Pathway
- (2009) M. S. Lee et al. JOURNAL OF IMMUNOLOGY
- Interferon regulatory factor-8 regulates bone metabolism by suppressing osteoclastogenesis
- (2009) Baohong Zhao et al. NATURE MEDICINE
- Pathway crosstalk between Ras/Raf and PI3K in promotion of M‐CSF‐induced MEK/ERK‐mediated osteoclast survival
- (2008) Elizabeth W. Bradley et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- PU.1 and NFATc1 mediate osteoclastic induction of the mouse β3 integrin promoter
- (2008) Tania N. Crotti et al. JOURNAL OF CELLULAR PHYSIOLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now