A Hybrid NRPS-PKS Gene Cluster Related to the Bleomycin Family of Antitumor Antibiotics in Alteromonas macleodii Strains
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Title
A Hybrid NRPS-PKS Gene Cluster Related to the Bleomycin Family of Antitumor Antibiotics in Alteromonas macleodii Strains
Authors
Keywords
Protein domains, Antibiotics, Gene prediction, Sequence alignment, Biosynthesis, Condensation, Antibiotic resistance, Phylogenetic analysis
Journal
PLoS One
Volume 8, Issue 9, Pages e76021
Publisher
Public Library of Science (PLoS)
Online
2013-09-20
DOI
10.1371/journal.pone.0076021
References
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- Antitumor Compounds from Marine Actinomycetes
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