Elevated Tolerance to Aneuploidy in Cancer Cells: Estimating the Fitness Effects of Chromosome Number Alterations by In Silico Modelling of Somatic Genome Evolution

Title
Elevated Tolerance to Aneuploidy in Cancer Cells: Estimating the Fitness Effects of Chromosome Number Alterations by In Silico Modelling of Somatic Genome Evolution
Authors
Keywords
Aneuploidy, Chromosomes, Fibroblasts, Chromosome structure and function, Natural selection, Colorectal cancer, Carcinogenesis, Karyotypes
Journal
PLoS One
Volume 8, Issue 7, Pages e70445
Publisher
Public Library of Science (PLoS)
Online
2013-07-25
DOI
10.1371/journal.pone.0070445

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