Anti-Tumor Activity of a miR-199-dependent Oncolytic Adenovirus

MicroRNA-Mediated Suppression of Oncolytic Adenovirus Replication in Human Liver

(2013) Erkko Ylösmäki et al.   PLoS One

Liver tumorigenicity promoted by microRNA-221 in a mouse transgenic model

(2012) Elisa Callegari et al.   HEPATOLOGY

Identification of miRNomes in Human Liver and Hepatocellular Carcinoma Reveals miR-199a/b-3p as Therapeutic Target for Hepatocellular Carcinoma

(2011) Jin Hou et al.   CANCER CELL

Enhanced antitumor efficacy of a novel fiber chimeric oncolytic adenovirus expressing p53 on hepatocellular carcinoma

(2011) Wei Chen et al.   CANCER LETTERS

Construction of an Oncolytic Herpes Simplex Virus That Precisely Targets Hepatocellular Carcinoma Cells

(2011) Xinping Fu et al.   MOLECULAR THERAPY

MicroRNA Controlled Adenovirus Mediates Anti-Cancer Efficacy without Affecting Endogenous MicroRNA Activity

(2011) Ryan Cawood et al.   PLoS One

Use of MicroRNA Let-7 to Control the Replication Specificity of Oncolytic Adenovirus in Hepatocellular Carcinoma Cells

(2011) Huajun Jin et al.   PLoS One

miR-199a-3p targets CD44 and reduces proliferation of CD44 positive hepatocellular carcinoma cell lines

(2010) Jon C. Henry et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MiR-199a-3p Regulates mTOR and c-Met to Influence the Doxorubicin Sensitivity of Human Hepatocarcinoma Cells

(2010) Francesca Fornari et al.   CANCER RESEARCH

Double-Detargeted Oncolytic Adenovirus Shows Replication Arrest in Liver Cells and Retains Neuroendocrine Cell Killing Ability

(2010) Justyna Leja et al.   PLoS One

Combination of adenoviral virotherapy and temozolomide chemotherapy eradicates malignant glioma through autophagic and apoptotic cell death in vivo

(2009) I V Ulasov et al.   BRITISH JOURNAL OF CANCER

A Phase I Study of Telomerase-specific Replication Competent Oncolytic Adenovirus (Telomelysin) for Various Solid Tumors

(2009) John Nemunaitis et al.   MOLECULAR THERAPY

Exploiting and antagonizing microRNA regulation for therapeutic and experimental applications

(2009) Brian D. Brown et al.   NATURE REVIEWS GENETICS

Use of Tissue-Specific MicroRNA to Control Pathology of Wild-Type Adenovirus without Attenuation of Its Ability to Kill Cancer Cells

(2009) Ryan Cawood et al.   PLoS Pathogens

A phase I trial of intratumoral administration of recombinant oncolytic adenovirus overexpressing HSP70 in advanced solid tumor patients

(2008) J-L Li et al.   GENE THERAPY

Gene therapy progress and prospects cancer: oncolytic viruses

(2008) T-C Liu et al.   GENE THERAPY

MicroRNAmiR-199a*Regulates theMETProto-oncogene and the Downstream Extracellular Signal-regulated Kinase 2 (ERK2)

(2008) Seonhoe Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Generation of a Conditionally Replicating Adenovirus Based on Targeted Destruction of E1A mRNA by a Cell Type-Specific MicroRNA

(2008) E. Ylosmaki et al.   JOURNAL OF VIROLOGY

MicroRNAs and the Regulation of Vector Tropism

(2008) Elizabeth J Kelly et al.   MOLECULAR THERAPY

Engineering microRNA responsiveness to decrease virus pathogenicity

(2008) Elizabeth J Kelly et al.   NATURE MEDICINE

Sorafenib in Advanced Hepatocellular Carcinoma

(2008) Josep M. Llovet et al.   NEW ENGLAND JOURNAL OF MEDICINE