Targeting p35/Cdk5 Signalling via CIP-Peptide Promotes Angiogenesis in Hypoxia

Inhibition of calpain-regulated p35/cdk5 plays a central role in sildenafil-induced protection against chemical hypoxia produced by malonate

(2013) Lucía Barros-Miñones et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cyclin-dependent kinase 5 regulates E2F transcription factor through phosphorylation of Rb protein in neurons

(2012) Akira Futatsugi et al.   CELL CYCLE

Cyclin-Dependent Kinase Inhibition With Roscovitine: Neuroprotection in Acute Ischemic Stroke

(2012) S Timsit et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Opticin Exerts Its Anti-angiogenic Activity by Regulating Extracellular Matrix Adhesiveness

(2012) Magali M. Le Goff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The protective effects of tanshinone IIA on neurotoxicity induced by β-amyloid protein through calpain and the p35/Cdk5 pathway in primary cortical neurons

(2012) Li-Li Shi et al.   NEUROCHEMISTRY INTERNATIONAL

Going out of the brain: Non-nervous system physiological and pathological functions of Cdk5

(2011) Erick Contreras-Vallejos et al.   CELLULAR SIGNALLING

The liquid overlay technique is the key to formation of co-culture spheroids consisting of primary osteoblasts, fibroblasts and endothelial cells

(2011) Wolfgang Metzger et al.   CYTOTHERAPY

Histone deacetylase inhibitors enhance endothelial cell sprouting angiogenesis in vitro

(2011) Guang Jin et al.   SURGERY

Anti-angiogenic potential of small molecular inhibitors of cyclin dependent kinases in vitro

(2010) Stefan Zahler et al.   ANGIOGENESIS

Cdk5 interacts with Hif-1α in neurons: A new hypoxic signalling mechanism?

(2010) Xanthi Antoniou et al.   BRAIN RESEARCH

The neuronal p35 activator of Cdk5 is a novel F-actin binding and bundling protein

(2010) Lisheng He et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cyclin-dependent Kinase 5 Regulates Endothelial Cell Migration and Angiogenesis

(2010) Johanna Liebl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Brassica Exon Array for Whole-Transcript Gene Expression Profiling

(2010) Christopher G. Love et al.   PLoS One

Evaluation of Soluble Junctional Adhesion Molecule-A as a Biomarker of Human Brain Endothelial Barrier Breakdown

(2010) Axel Haarmann et al.   PLoS One

Targeting Cdk5 Activity in Neuronal Degeneration and Regeneration

(2009) Jyotshnabala Kanungo et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Pharmacodynamic Effects of Seliciclib, an Orally Administered Cell Cycle Modulator, in Undifferentiated Nasopharyngeal Cancer

(2009) W.-S. Hsieh et al.   CLINICAL CANCER RESEARCH

Essential Role of Cytoplasmic cdk5 and Prx2 in Multiple Ischemic Injury Models, In Vivo

(2009) J. Rashidian et al.   JOURNAL OF NEUROSCIENCE

Talin phosphorylation by Cdk5 regulates Smurf1-mediated talin head ubiquitylation and cell migration

(2009) Cai Huang et al.   NATURE CELL BIOLOGY

Cyclin-dependent kinase-5 targeting for ischaemic stroke

(2008) Mark Slevin et al.   CURRENT OPINION IN PHARMACOLOGY

Distinct functions of Cdk5(Y15) phosphorylation and Cdk5 activity in stress fiber formation and organization

(2008) Fengyu Qiao et al.   EXPERIMENTAL CELL RESEARCH

Roscovitine up-regulates p53 protein and induces apoptosis in human HeLaS3cervix carcinoma cells

(2008) Józefa Węsierska-Gądek et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

A novel calpain inhibitor, ((1S)-1((((1S)-1-benzyl-3-cyclopropylamino-2,3-di-oxopropyl)amino)carbonyl)-3-methylbutyl) carbamic acid 5-methoxy-3-oxapentyl ester, protects neuronal cells from cerebral ischemia-induced damage in mice

(2008) A. Koumura et al.   NEUROSCIENCE