Anti-Pancreatic Cancer Deliverables from Sea: First-Hand Evidence on the Efficacy, Molecular Targets and Mode of Action for Multifarious Polyphenols from Five Different Brown-Algae

KRAS above and beyond – EGFR in pancreatic cancer

(2015) Jens T. Siveke et al.   Oncotarget

High Expression of HIF1a Is a Predictor of Clinical Outcome in Patients with Pancreatic Ductal Adenocarcinomas and Correlated to PDGFA, VEGF, and bFGF

(2015) Andreas-Claudius Hoffmann et al.   NEOPLASIA

hTERT-siRNA Could Potentiate the Cytotoxic Effect of Gemcitabine to Pancreatic Cancer Cells Bxpc-3

(2012) Jing Tan et al.   Experimental and Clinical Transplantation

NF-κB as a target for pancreatic cancer therapy

(2012) Carmine Carbone et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Akt/mTOR signaling pathway is crucial for gemcitabine resistance induced by Annexin II in pancreatic cancer cells

(2012) Shingo Kagawa et al.   JOURNAL OF SURGICAL RESEARCH

Evaluation of Antioxidant and Immunity-Enhancing Activities of Sargassum pallidum Aqueous Extract in Gastric Cancer Rats

(2012) Rui-Li Zhang et al.   MOLECULES

Aqueous Extracts of the Edible Gracilaria tenuistipitata are Protective Against H2O2-Induced DNA Damage, Growth Inhibition, and Cell Cycle Arrest

(2012) Jing-Iong Yang et al.   MOLECULES

MUC1 regulates PDGFA expression during pancreatic cancer progression

(2012) M Sahraei et al.   ONCOGENE

Fucoidan extract derived from Undaria pinnatifida inhibits angiogenesis by human umbilical vein endothelial cells

(2012) Fang Liu et al.   PHYTOMEDICINE

Metastatic Pancreatic Cancer Is Dependent on Oncogenic Kras in Mice

(2012) Meredith A. Collins et al.   PLoS One

Brivanib, a Dual FGF/VEGF Inhibitor, Is Active Both First and Second Line against Mouse Pancreatic Neuroendocrine Tumors Developing Adaptive/Evasive Resistance to VEGF Inhibition

(2011) Elizabeth Allen et al.   CLINICAL CANCER RESEARCH

Molecular Targeted Approaches for Treatment of Pancreatic Cancer

(2011) Z.Q. Huang et al.   CURRENT PHARMACEUTICAL DESIGN

Enzyme-assistant extraction (EAE) of bioactive components: A useful approach for recovery of industrially important metabolites from seaweeds: A review

(2011) W.A.J.P. Wijesinghe et al.   FITOTERAPIA

Curcumin Regulates Low-Linear Energy Transfer γ-Radiation-Induced NFκB-Dependent Telomerase Activity in Human Neuroblastoma Cells

(2011) Natarajan Aravindan et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Radiation-triggered Tumor Necrosis Factor (TNF) α-NFκB Cross-signaling Favors Survival Advantage in Human Neuroblastoma Cells

(2011) Jamunarani Veeraraghavan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crosstalk between the canonical NF-κB and Notch signaling pathways inhibits Pparγ expression and promotes pancreatic cancer progression in mice

(2011) Eleni Maniati et al.   JOURNAL OF CLINICAL INVESTIGATION

Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy

(2011) Eric A Collisson et al.   NATURE MEDICINE

Impact of Curcumin, Raspberry Extract, and Neem Leaf Extract on Rel Protein-Regulated Cell Death/Radiosensitization in Pancreatic Cancer Cells

(2011) Jamunarani Veeraraghavan et al.   PANCREAS

Irreversible EGFR Inhibitor EKB-569 Targets Low-LET γ-Radiation-Triggered Rel Orchestration and Potentiates Cell Death in Squamous Cell Carcinoma

(2011) Natarajan Aravindan et al.   PLoS One

Fucoidan Extract Induces Apoptosis in MCF-7 Cells via a Mechanism Involving the ROS-Dependent JNK Activation and Mitochondria-Mediated Pathways

(2011) Zhongyuan Zhang et al.   PLoS One

Molecular biology of pancreatic cancer

(2011) Miroslav Zavoral   WORLD JOURNAL OF GASTROENTEROLOGY

Anticancer Drugs from Marine Flora: An Overview

(2011) N. Sithranga Boopathy et al.   Journal of Oncology

NFκB activity and transcriptional responses in human breast adenocarcinoma cells after single and fractionated irradiation

(2010) Rakhesh Madhusoodhanan et al.   CANCER BIOLOGY & THERAPY

Breaking the NF- B and STAT3 Alliance Inhibits Inflammation and Pancreatic Tumorigenesis

(2010) Y.-J. Surh et al.   Cancer Prevention Research

Direct Inhibition of Elastase Activity by Indole-3-Carbinol Triggers a CD40-TRAF Regulatory Cascade That Disrupts NF-κB Transcriptional Activity in Human Breast Cancer Cells

(2010) Ida Aronchik et al.   CANCER RESEARCH

Optimal treatment of metastatic pancreatic cancer

(2010) D. Cunningham et al.   GUT

Knockdown of hTERT by SiRNA suppresses growth of Capan-2 human pancreatic cancer cell via the inhibition of expressions of Bcl-2 and COX-2

(2010) Ying Qiang ZHONG et al.   Journal of Digestive Diseases

Inhibition of Radiation-Induced DNA Repair and Prosurvival Pathways Contributes to Vorinostat-Mediated Radiosensitization of Pancreatic Cancer Cells

(2010) Amit Deorukhkar et al.   PANCREAS

Positive Regulation of Human Telomerase Reverse Transcriptase Gene Expression and Telomerase Activity by DNA Methylation in Pancreatic Cancer

(2009) Alpana Kumari et al.   ANNALS OF SURGICAL ONCOLOGY

A Gene Expression Signature Associated with “K-Ras Addiction” Reveals Regulators of EMT and Tumor Cell Survival

(2009) Anurag Singh et al.   CANCER CELL

Antioxidant, Mutagenic, and Antimutagenic Activity of Frozen Fruits

(2008) Patrícia D.S. Spada et al.   JOURNAL OF MEDICINAL FOOD