Involvement of ERK-Nrf-2 Signaling in Ionizing Radiation Induced Cell Death in Normal and Tumor Cells

Dimethoxycurcumin, a metabolically stable analogue of curcumin, exhibits anti-inflammatory activities in murine and human lymphocytes

(2011) Raghavendra S. Patwardhan et al.   BIOCHEMICAL PHARMACOLOGY

Pro-oxidants ameliorate radiation-induced apoptosis through activation of the calcium–ERK1/2–Nrf2 pathway

(2011) Nazir M. Khan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

(2011) Gina M. DeNicola et al.   NATURE

Oxidative stress and oxidative damage in chemical carcinogenesis

(2011) James E. Klaunig et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Targeting inflammatory pathways for tumor radiosensitization

(2010) Amit Deorukhkar et al.   BIOCHEMICAL PHARMACOLOGY

Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential

(2010) Ananta Paine et al.   BIOCHEMICAL PHARMACOLOGY

Ionizing Radiation Activates the Nrf2 Antioxidant Response

(2010) J. T. McDonald et al.   CANCER RESEARCH

Up-regulation of heme oxygenase-1 expression through CaMKII-ERK1/2-Nrf2 signaling mediates the anti-inflammatory effect of bisdemethoxycurcumin in LPS-stimulated macrophages

(2010) An Na Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidative stress, inflammation, and cancer: How are they linked?

(2010) Simone Reuter et al.   FREE RADICAL BIOLOGY AND MEDICINE

Therapeutic strategies by modulating oxygen stress in cancer and inflammation

(2009) Jun Fang et al.   ADVANCED DRUG DELIVERY REVIEWS

Targeting Inflammatory Pathways for Prevention and Therapy of Cancer: Short-Term Friend, Long-Term Foe

(2009) B. B. Aggarwal et al.   CLINICAL CANCER RESEARCH

Nrf2:INrf2 (Keap1) signaling in oxidative stress

(2009) James W. Kaspar et al.   FREE RADICAL BIOLOGY AND MEDICINE

Anti-inflammatory effects of plumbagin are mediated by inhibition of NF-kappaB activation in lymphocytes

(2009) Rahul Checker et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress

(2009) Truyen Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Association of reactive oxygen species levels and radioresistance in cancer stem cells

(2009) Maximilian Diehn et al.   NATURE

Phosphorylation of Nrf2 at Multiple Sites by MAP Kinases Has a Limited Contribution in Modulating the Nrf2-Dependent Antioxidant Response

(2009) Zheng Sun et al.   PLoS One

Molecular radiation biology: Perspectives for radiation oncology

(2009) H. Peter Rodemann   RADIOTHERAPY AND ONCOLOGY

NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer

(2009) John D. Hayes et al.   TRENDS IN BIOCHEMICAL SCIENCES

Loss of Keap1 Function Activates Nrf2 and Provides Advantages for Lung Cancer Cell Growth

(2008) T. Ohta et al.   CANCER RESEARCH

RNAi-Mediated Silencing of Nuclear Factor Erythroid-2-Related Factor 2 Gene Expression in Non-Small Cell Lung Cancer Inhibits Tumor Growth and Increases Efficacy of Chemotherapy

(2008) A. Singh et al.   CANCER RESEARCH

Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2

(2008) X.-J. Wang et al.   CARCINOGENESIS

Immunomodulatory and radioprotective effects of lignans derived from fresh nutmeg mace (Myristica fragrans) in mammalian splenocytes

(2008) Rahul Checker et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Molecular mechanisms of Nrf2-mediated antioxidant response

(2008) Wenge Li et al.   MOLECULAR CARCINOGENESIS

Nrf2 as a Master Redox Switch in Turning on the Cellular Signaling Involved in the Induction of Cytoprotective Genes by Some Chemopreventive Phytochemicals

(2008) Young-Joon Surh et al.   PLANTA MEDICA

The Nrf2–Keap1 defence pathway: Role in protection against drug-induced toxicity

(2007) Ian M. Copple et al.   TOXICOLOGY