Senescent Fibroblasts Enhance Early Skin Carcinogenic Events via a Paracrine MMP-PAR-1 Axis

EMT and Dissemination Precede Pancreatic Tumor Formation

(2012) Andrew D. Rhim et al.   CELL

PAR-1 and Thrombin: The Ties That Bind the Microenvironment to Melanoma Metastasis

(2011) M. Zigler et al.   CANCER RESEARCH

IL-8 Signaling Plays a Critical Role in the Epithelial-Mesenchymal Transition of Human Carcinoma Cells

(2011) R. I. Fernando et al.   CANCER RESEARCH

Senescent cells develop a PARP-1 and nuclear factor- B-associated secretome (PNAS)

(2011) M. Ohanna et al.   GENES & DEVELOPMENT

Cancer early dissemination: cancerous epithelial-mesenchymal transdifferentiation and transforming growth factor   signalling

(2011) H. Sabe   JOURNAL OF BIOCHEMISTRY

Temporal and Spatial Cooperation of Snail1 and Twist1 during Epithelial-Mesenchymal Transition Predicts for Human Breast Cancer Recurrence

(2011) D. D. Tran et al.   MOLECULAR CANCER RESEARCH

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

The activation of Proteinase-Activated Receptor-1 (PAR1) mediates gastric cancer cell proliferation and invasion

(2010) Daisuke Fujimoto et al.   BMC CANCER

Cancer Statistics, 2010

(2010) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Nonmelanoma Skin Cancer and the Risk of Second Primary Cancers: a Systematic Review

(2010) L. Wheless et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

V600EBraf induces gastrointestinal crypt senescence and promotes tumour progression through enhanced CpG methylation ofp16INK4a

(2010) Linda A. S. Carragher et al.   EMBO Molecular Medicine

Thrombin promotes actin stress fiber formation in RPE through Rho/ROCK-mediated MLC phosphorylation

(2010) Ariadna Yolanda Ruiz-Loredo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Tumor cells disseminate early, but immunosurveillance limits metastatic outgrowth, in a mouse model of melanoma

(2010) Jo Eyles et al.   JOURNAL OF CLINICAL INVESTIGATION

A Human-Like Senescence-Associated Secretory Phenotype Is Conserved in Mouse Cells Dependent on Physiological Oxygen

(2010) Jean-Philippe Coppé et al.   PLoS One

MnSOD Upregulation Induces Autophagic Programmed Cell Death in Senescent Keratinocytes

(2010) Emeric Deruy et al.   PLoS One

Senescent Keratinocytes Die by Autophagic Programmed Cell Death

(2009) Karo Gosselin et al.   AMERICAN JOURNAL OF PATHOLOGY

Senescence-Associated Oxidative DNA Damage Promotes the Generation of Neoplastic Cells

(2009) K. Gosselin et al.   CANCER RESEARCH

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

A novel signaling pathway of tissue kallikrein in promoting keratinocyte migration: Activation of proteinase-activated receptor 1 and epidermal growth factor receptor

(2009) Lin Gao et al.   EXPERIMENTAL CELL RESEARCH

In Situ Zymography and Immunolabeling in Fixed and Decalcified Craniofacial Tissues

(2009) Isabel M. Porto et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Papillary hyperplasia of the gallbladder in pancreaticobiliary maljunction represents a senescence-related lesion induced by lysolecithin

(2009) Junpei Yamaguchi et al.   LABORATORY INVESTIGATION

A matrix metalloproteinase-1/protease activated receptor-1 signaling axis promotes melanoma invasion and metastasis

(2009) J S Blackburn et al.   ONCOGENE

The Met tyrosine kinase receptor in development and cancer

(2008) Alessandra Gentile et al.   CANCER AND METASTASIS REVIEWS

Systemic Spread Is an Early Step in Breast Cancer

(2008) Yves Hüsemann et al.   CANCER CELL

Induction of EMT by Twist Proteins as a Collateral Effect of Tumor-Promoting Inactivation of Premature Senescence

(2008) Stéphane Ansieau et al.   CANCER CELL

Matrix metalloproteinases stimulate epithelial-mesenchymal transition during tumor development

(2008) Lidiya S. Orlichenko et al.   CLINICAL & EXPERIMENTAL METASTASIS

Ets-1 triggers and orchestrates the malignant phenotype of mammary cancer cells within their matrix environment

(2008) Alessandro Furlan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Aging Alters Functionally Human Dermal Papillary Fibroblasts but Not Reticular Fibroblasts: A New View of Skin Morphogenesis and Aging

(2008) Solène Mine et al.   PLoS One

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY