Francisella tularensis subsp. tularensis Induces a Unique Pulmonary Inflammatory Response: Role of Bacterial Gene Expression in Temporal Regulation of Host Defense Responses

Notch Activation by the Metalloproteinase ADAM17 Regulates Myeloproliferation and Atopic Barrier Immunity by Suppressing Epithelial Cytokine Synthesis

(2012) Aditya Murthy et al.   IMMUNITY

Sensing and reacting to microbes through the inflammasomes

(2012) Luigi Franchi et al.   NATURE IMMUNOLOGY

Growth conditions and environmental factors impact aerosolization but not virulence of Francisella tularensis infection in mice

(2012) Seth A. Faith et al.   Frontiers in Cellular and Infection Microbiology

Adam17-dependent shedding limits early neutrophil influx but does not alter early monocyte recruitment to inflammatory sites

(2011) J. Tang et al.   BLOOD

Elevated AIM2-mediated pyroptosis triggered by hypercytotoxic Francisella mutant strains is attributed to increased intracellular bacteriolysis

(2011) Kaitian Peng et al.   CELLULAR MICROBIOLOGY

Insight into Bacterial Virulence Mechanisms against Host Immune Response via the Yersinia pestis-Human Protein-Protein Interaction Network

(2011) Huiying Yang et al.   INFECTION AND IMMUNITY

The Acid Phosphatase AcpA Is SecretedIn Vitroand in Macrophages by Francisella spp.

(2011) Shipan Dai et al.   INFECTION AND IMMUNITY

Role of the Yersinia pestis Ail Protein in Preventing a Protective Polymorphonuclear Leukocyte Response during Bubonic Plague

(2011) B. Joseph Hinnebusch et al.   INFECTION AND IMMUNITY

IFN-  Mediates Suppression of IL-12p40 in Human Dendritic Cells following Infection with Virulent Francisella tularensis

(2011) T. J. Bauler et al.   JOURNAL OF IMMUNOLOGY

Gene expression following low dose inhalational Francisella tularensis (SchuS4) exposure in Balb/c mice and the potential role of the epithelium and cell adhesion

(2011) Jonathan David et al.   MICROBES AND INFECTION

The biochemical properties of the Francisella pathogenicity island (FPI)-encoded proteins IglA, IglB, IglC, PdpB and DotU suggest roles in type VI secretion

(2011) O. M. de Bruin et al.   MICROBIOLOGY-SGM

Host-Adaptation of Francisella tularensis Alters the Bacterium's Surface-Carbohydrates to Hinder Effectors of Innate and Adaptive Immunity

(2011) Tiffany M. Zarrella et al.   PLoS One

The Subversion of the Immune System by Francisella Tularensis

(2011) Catharine M. Bosio   Frontiers in Microbiology

The type IV pilin, PilA, is required for full virulence of Francisella tularensis subspecies tularensis

(2010) Anna-Lena Forslund et al.   BMC MICROBIOLOGY

NOD1 and NOD2 regulation of pulmonary innate immunity to Legionella pneumophila

(2010) William R. Berrington et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Francisella tularensis  pyrF Mutants Show that Replication in Nonmacrophages Is Sufficient for Pathogenesis In Vivo

(2010) J. Horzempa et al.   INFECTION AND IMMUNITY

Regulation of Virulence Gene Transcripts by the Francisella novicida Orphan Response Regulator PmrA: Role of Phosphorylation and Evidence of MglA/SspA Interaction

(2010) B. L. Bell et al.   INFECTION AND IMMUNITY

Tularemia Pneumonia

(2010) Lora D. Thomas et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

The many faces of the YopM effector from plague causative bacterium Yersinia pestis and its implications for host immune modulation

(2010) Venkataramanan Soundararajan et al.   Innate Immunity

Francisella tularensisAntioxidants Harness Reactive Oxygen Species to Restrict Macrophage Signaling and Cytokine Production

(2010) Amanda A. Melillo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphatidylinositol 3-Kinase Activation Attenuates the TLR2-Mediated Macrophage Proinflammatory Cytokine Response to Francisella tularensis Live Vaccine Strain

(2010) E. A. Medina et al.   JOURNAL OF IMMUNOLOGY

Francisella tularensis Suppresses the Proinflammatory Response of Endothelial Cells via the Endothelial Protein C Receptor

(2010) D. C. Bublitz et al.   JOURNAL OF IMMUNOLOGY

Genetic identification of unique immunological responses in mice infected with virulent and attenuated Francisella tularensis

(2010) Luke C. Kingry et al.   MICROBES AND INFECTION

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

(2010) Vijay A K Rathinam et al.   NATURE IMMUNOLOGY

The Role of the Francisella Tularensis Pathogenicity Island in Type VI Secretion, Intracellular Survival, and Modulation of Host Cell Signaling

(2010) Jeanette E. Bröms et al.   Frontiers in Microbiology

Role of Toll-like receptor 5 in the innate immune response to acute P. aeruginosa pneumonia

(2009) Amy E. Morris et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Contributions of Francisella tularensis subsp. novicida Chitinases and Sec Secretion System to Biofilm Formation on Chitin

(2009) J. J. Margolis et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

ROCK1 functions as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability

(2009) S. Vemula et al.   BLOOD

Molecular Epidemiology ofFrancisella tularensisin the United States

(2009) Kiersten J. Kugeler et al.   CLINICAL INFECTIOUS DISEASES

A tolC Mutant of Francisella tularensis Is Hypercytotoxic Compared to the Wild Type and Elicits Increased Proinflammatory Responses from Host Cells

(2009) G. J. Platz et al.   INFECTION AND IMMUNITY

The Presence of CD14 Overcomes Evasion of Innate Immune Responses by Virulent Francisella tularensis in Human Dendritic Cells In Vitro and Pulmonary Cells In Vivo

(2009) J. C. Chase et al.   INFECTION AND IMMUNITY

The Francisella tularensis pathogenicity island encodes a secretion system that is required for phagosome escape and virulence

(2009) Jeffrey R. Barker et al.   MOLECULAR MICROBIOLOGY

Identification of Genes Contributing to the Virulence of Francisella tularensis SCHU S4 in a Mouse Intradermal Infection Model

(2009) Konstantin Kadzhaev et al.   PLoS One

Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus

(2009) C. R. Baskin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid Polymerase Chain Reaction-based Screening Assay for Bacterial Biothreat Agents

(2008) Samuel Yang et al.   ACADEMIC EMERGENCY MEDICINE

Diverse Myeloid and Lymphoid Cell Subpopulations Produce Gamma Interferon during Early Innate Immune Responses to Francisella tularensis Live Vaccine Strain

(2008) R. De Pascalis et al.   INFECTION AND IMMUNITY

NK Cells and Gamma Interferon Coordinate the Formation and Function of Hepatic Granulomas in Mice Infected with the Francisella tularensis Live Vaccine Strain

(2008) S. M. Bokhari et al.   INFECTION AND IMMUNITY

Identification of an Essential Francisella tularensis subsp. tularensis Virulence Factor

(2008) A. Qin et al.   INFECTION AND IMMUNITY

Infected-Host-Cell Repertoire and Cellular Response in the Lung following Inhalation of Francisella tularensis Schu S4, LVS, or U112

(2008) J. D. Hall et al.   INFECTION AND IMMUNITY

Direct and Indirect Impairment of Human Dendritic Cell Function by Virulent Francisella tularensis Schu S4

(2008) J. C. Chase et al.   INFECTION AND IMMUNITY

NK cells activated in vivo by bacterial DNA control the intracellular growth of Francisella tularensis LVS

(2008) K ELKINS et al.   MICROBES AND INFECTION

Francisella gains a survival advantage within mononuclear phagocytes by suppressing the host IFNγ response

(2008) Kishore V.L. Parsa et al.   MOLECULAR IMMUNOLOGY

Microarray Analysis of Human Monocytes Infected with Francisella tularensis Identifies New Targets of Host Response Subversion

(2008) Jonathan P. Butchar et al.   PLoS One

A Francisella Mutant in Lipid A Carbohydrate Modification Elicits Protective Immunity

(2008) Duangjit Kanistanon et al.   PLoS Pathogens

H5N1 and 1918 Pandemic Influenza Virus Infection Results in Early and Excessive Infiltration of Macrophages and Neutrophils in the Lungs of Mice

(2008) Lucy A. Perrone et al.   PLoS Pathogens