Expression, Regulation and Putative Nutrient-Sensing Function of Taste GPCRs in the Heart

Extraoral bitter taste receptors as mediators of off-target drug effects

(2012) Adam A. Clark et al.   FASEB JOURNAL

The G Protein-Coupled Taste Receptor T1R1/T1R3 Regulates mTORC1 and Autophagy

(2012) Eric M. Wauson et al.   MOLECULAR CELL

Multiple tyrosine metabolites are GPR35 agonists

(2012) Huayun Deng et al.   Scientific Reports

Low Affinity GPCRs for Metabolic Intermediates: Challenges for Pharmacologists

(2012) Nicola J. Smith   Frontiers in Endocrinology

KIF6, LPA, TAS2R50, and VAMP8 genetic variation, low density lipoprotein cholesterol lowering response to pravastatin, and heart disease risk reduction in the elderly

(2011) Hironobu Akao et al.   ATHEROSCLEROSIS

Gut bitter taste receptor signalling induces ABCB1 through a mechanism involving CCK

(2011) Tae-Il Jeon et al.   BIOCHEMICAL JOURNAL

GPCR expression in tissues and cells: Are the optimal receptors being used as drug targets?

(2011) PA Insel et al.   BRITISH JOURNAL OF PHARMACOLOGY

Genetic Identification of GnRH Receptor Neurons: A New Model for Studying Neural Circuits Underlying Reproductive Physiology in the Mouse Brain

(2011) Shuping Wen et al.   ENDOCRINOLOGY

Gustatory and extragustatory functions of mammalian taste receptors

(2011) Maik Behrens et al.   PHYSIOLOGY & BEHAVIOR

Bitter taste receptors and α-gustducin regulate the secretion of ghrelin with functional effects on food intake and gastric emptying

(2011) Sara Janssen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression of taste receptors in Solitary Chemosensory Cells of rodent airways

(2011) Marco Tizzano et al.   BMC Pulmonary Medicine

Modulation of Bitter Taste Perception by a Small Molecule hTAS2R Antagonist

(2010) Jay P. Slack et al.   CURRENT BIOLOGY

The nuclear receptor PPARγ individually responds to serotonin- and fatty acid-metabolites

(2010) Tsuyoshi Waku et al.   EMBO JOURNAL

Heat generates oxidized linoleic acid metabolites that activate TRPV1 and produce pain in rodents

(2010) Amol M. Patwardhan et al.   JOURNAL OF CLINICAL INVESTIGATION

Bitter taste receptors on airway smooth muscle bronchodilate by localized calcium signaling and reverse obstruction

(2010) Deepak A Deshpande et al.   NATURE MEDICINE

The Molecular Receptive Ranges of Human TAS2R Bitter Taste Receptors

(2009) Wolfgang Meyerhof et al.   CHEMICAL SENSES

Trace Amine-Associated Receptors as Emerging Therapeutic Targets

(2009) T. D. Sotnikova et al.   MOLECULAR PHARMACOLOGY

Molecular Pharmacology of Promiscuous Seven Transmembrane Receptors Sensing Organic Nutrients

(2009) P. Wellendorph et al.   MOLECULAR PHARMACOLOGY

Identification of Potential Pharmacological Targets by Analysis of the Comprehensive G Protein-Coupled Receptor Repertoire in the Four Cardiac Chambers

(2009) T. Moore-Morris et al.   MOLECULAR PHARMACOLOGY

Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus

(2008) David G Simmons et al.   BMC GENOMICS

Anatomical Profiling of G Protein-Coupled Receptor Expression

(2008) Jean B. Regard et al.   CELL

Expression of taste molecules in the upper gastrointestinal tract in humans with and without type 2 diabetes

(2008) R L Young et al.   GUT

An energy supply network of nutrient absorption coordinated by calcium and T1R taste receptors in rat small intestine

(2008) Oliver J. Mace et al.   JOURNAL OF PHYSIOLOGY-LONDON

Structural diversity of G protein-coupled receptors and significance for drug discovery

(2008) Malin C. Lagerström et al.   NATURE REVIEWS DRUG DISCOVERY

Bitter Taste Receptors Influence Glucose Homeostasis

(2008) Cedrick D. Dotson et al.   PLoS One

Association of Gene Variants With Incident Myocardial Infarction in the Cardiovascular Health Study

(2007) Dov Shiffman et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY