Comprehensive Genomic Characterization of Cutaneous Malignant Melanoma Cell Lines Derived from Metastatic Lesions by Whole-Exome Sequencing and SNP Array Profiling

The Nonreceptor-Type Tyrosine Phosphatase PTPN13 Is a Tumor Suppressor Gene in Non–Small Cell Lung Cancer

(2012) Marianna Scrima et al.   AMERICAN JOURNAL OF PATHOLOGY

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

A Landscape of Driver Mutations in Melanoma

(2012) Eran Hodis et al.   CELL

Systematic identification of genomic markers of drug sensitivity in cancer cells

(2012) Mathew J. Garnett et al.   NATURE

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Combined BRAF and MEK Inhibition in Melanoma with BRAF V600 Mutations

(2012) Keith T. Flaherty et al.   NEW ENGLAND JOURNAL OF MEDICINE

Delving into somatic variation in sporadic melanoma

(2012) Vijay Walia et al.   Pigment Cell & Melanoma Research

Reviewing the somatic genetics of melanoma: from current to future analytical approaches

(2012) Ken Dutton-Regester et al.   Pigment Cell & Melanoma Research

Aberrant methylation of N-methyl-D-aspartate receptor type 2B (NMDAR2B) in non-small cell carcinoma

(2011) Hajime Tamura et al.   BMC CANCER

Glutamatergic Pathway Targeting in Melanoma: Single-Agent and Combinatorial Therapies

(2011) H. J. Lee et al.   CLINICAL CANCER RESEARCH

Analysis of the disintegrin-metalloproteinases family reveals ADAM29 and ADAM7 are often mutated in melanoma

(2011) Xiaomu Wei et al.   HUMAN MUTATION

Glutamatergic Signaling Maintains the Epithelial Phenotype of Proximal Tubular Cells

(2011) M. Bozic et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Exon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma

(2011) Todd D Prickett et al.   NATURE GENETICS

Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing

(2011) Mitchell S Stark et al.   NATURE GENETICS

Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma

(2011) Sergey I Nikolaev et al.   NATURE GENETICS

Exome sequencing identifies GRIN2A as frequently mutated in melanoma

(2011) Xiaomu Wei et al.   NATURE GENETICS

Reversing Melanoma Cross-Resistance to BRAF and MEK Inhibitors by Co-Targeting the AKT/mTOR Pathway

(2011) Mohammad Atefi et al.   PLoS One

Galectin-3 binding protein promotes cell motility in colon cancer by stimulating the shedding of protein tyrosine phosphatase kappa by proprotein convertase 5

(2010) Yong-Sam Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mutational and Functional Analysis Reveals ADAMTS18 Metalloproteinase as a Novel Driver in Melanoma

(2010) X. Wei et al.   MOLECULAR CANCER RESEARCH

G protein-coupled receptors: novel targets for drug discovery in cancer

(2010) Rosamaria Lappano et al.   NATURE REVIEWS DRUG DISCOVERY

Advances in understanding cancer genomes through second-generation sequencing

(2010) Matthew Meyerson et al.   NATURE REVIEWS GENETICS

Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

(2010) Keith T. Flaherty et al.   NEW ENGLAND JOURNAL OF MEDICINE

Analysis of the genome to personalize therapy for melanoma

(2010) M A Davies et al.   ONCOGENE

Higher sensitivity of Adamts12-deficient mice to tumor growth and angiogenesis

(2010) M El Hour et al.   ONCOGENE

Proteome profiling of immortalization-to-senescence transition of human breast epithelial cells identified MAP2K3 as a senescence-promoting protein which is downregulated in human breast cancer

(2010) Min Jia et al.   Proteomics Clinical Applications

Promoter CpG island hypermethylation during breast cancer progression

(2010) So Yeon Park et al.   VIRCHOWS ARCHIV

The presence of aberrant DNA methylation in noncancerous esophageal mucosae in association with smoking history

(2009) Daiji Oka et al.   CANCER

The ADAMTS12 metalloprotease gene is epigenetically silenced in tumor cells and transcriptionally activated in the stroma during progression of colon cancer

(2009) A. Moncada-Pazos et al.   JOURNAL OF CELL SCIENCE

Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4

(2009) Todd D Prickett et al.   NATURE GENETICS

Tumor-mediated liver X receptor-α activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses

(2009) Eduardo J Villablanca et al.   NATURE MEDICINE

Combined Targeting of BRAF and CRAF or BRAF and PI3K Effector Pathways Is Required for Efficacy in NRAS Mutant Tumors

(2009) Bijay S. Jaiswal et al.   PLoS One

Mutational Inactivation of PTPRD in Glioblastoma Multiforme and Malignant Melanoma

(2008) D. A. Solomon et al.   CANCER RESEARCH

Promoter hypermethylation of theADAM23gene in colorectal cancer cell lines and cancer tissues

(2008) Jin-Sung Choi et al.   INTERNATIONAL JOURNAL OF CANCER

Oncogenic activities of metabotropic glutamate receptor 1 (Grm1) in melanocyte transformation

(2008) Seung-Shick Shin et al.   Pigment Cell & Melanoma Research