CNF1 Increases Brain Energy Level, Counteracts Neuroinflammatory Markers and Rescues Cognitive Deficits in a Murine Model of Alzheimer's Disease

Neuropathologic substrates of Parkinson disease dementia

(2012) David J. Irwin et al.   ANNALS OF NEUROLOGY

Behavioral effects of Rho GTPase modulation in a model of Alzheimer's disease

(2012) Marco Musilli et al.   BEHAVIOURAL BRAIN RESEARCH

Multiple Defects in Energy Metabolism in Alzheimers Disease

(2012) I. L. Ferreira et al.   CURRENT DRUG TARGETS

APOE genotype alters glial activation and loss of synaptic markers in mice

(2012) Yuangui Zhu et al.   GLIA

High-energy compounds promote physiological processing of Alzheimer's amyloid-β precursor protein and boost cell survival in culture

(2012) Darrell R. Sawmiller et al.   JOURNAL OF NEUROCHEMISTRY

Astrocyte-Originated ATP Protects A 1-42-Induced Impairment of Synaptic Plasticity

(2012) E. S. Jung et al.   JOURNAL OF NEUROSCIENCE

CNF1 Improves Astrocytic Ability to Support Neuronal Growth and Differentiation In vitro

(2012) Fiorella Malchiodi-Albedi et al.   PLoS One

Astrocytes: Implications for Neuroinflammatory Pathogenesis of Alzheimers Disease

(2011) Chuanyu Li et al.   Current Alzheimer Research

Targeting Mitochondrial Bioenergetics for Alzheimers Prevention and Treatment

(2011) Jia Yao et al.   CURRENT PHARMACEUTICAL DESIGN

γ-Secretase Inhibitors and Modulators for the Treatment of Alzheimer's Disease: Disappointments and Hopes

(2011) Bruno P. Imbimbo et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Apolipoprotein E4 Exaggerates Diabetic Dyslipidemia and Atherosclerosis in Mice Lacking the LDL Receptor

(2011) L. A. Johnson et al.   DIABETES

Activation of Rho GTPases Triggers Structural Remodeling and Functional Plasticity in the Adult Rat Visual Cortex

(2011) C. Cerri et al.   JOURNAL OF NEUROSCIENCE

Cross-Talk between Apolipoprotein E and Cytokines

(2011) Hongliang Zhang et al.   MEDIATORS OF INFLAMMATION

Therapeutic Use of Creatine in Brain or Heart Ischemia: Available Data and Future Perspectives

(2011) Luisa Perasso et al.   MEDICINAL RESEARCH REVIEWS

Modulation of RhoGTPases Improves the Behavioral Phenotype and Reverses Astrocytic Deficits in a Mouse Model of Rett Syndrome

(2011) Bianca De Filippis et al.   NEUROPSYCHOPHARMACOLOGY

Cellular Source of Apolipoprotein E4 Determines Neuronal Susceptibility to Excitotoxic Injury in Transgenic Mice

(2010) Manuel Buttini et al.   AMERICAN JOURNAL OF PATHOLOGY

Mitochondria and Neuroplasticity

(2010) Aiwu Cheng et al.   ASN Neuro

Apolipoprotein E4 Domain Interaction Mediates Detrimental Effects on Mitochondria and Is a Potential Therapeutic Target for Alzheimer Disease

(2010) Hung-Kai Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Synaptic Rac1 Activity, Long-Term Potentiation Maintenance, and Learning and Memory by BCR and ABR Rac GTPase-Activating Proteins

(2010) D. Oh et al.   JOURNAL OF NEUROSCIENCE

CDKL5, a Protein Associated with Rett Syndrome, Regulates Neuronal Morphogenesis via Rac1 Signaling

(2010) Q. Chen et al.   JOURNAL OF NEUROSCIENCE

Can novel therapeutics halt the amyloid cascade?

(2010) Niels D Prins et al.   Alzheimers Research & Therapy

APOE 4 polymorphism results in early cognitive deficits in an EAE model

(2009) Jiang-long Tu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulation of spine and synapse formation by activity-dependent intracellular signaling pathways

(2009) Takeo Saneyoshi et al.   CURRENT OPINION IN NEUROBIOLOGY

Different Rho GTPase–dependent signaling pathways initiate sequential steps in the consolidation of long-term potentiation

(2009) Christopher S. Rex et al.   JOURNAL OF CELL BIOLOGY

ApoE4 Decreases Spine Density and Dendritic Complexity in Cortical Neurons In Vivo

(2009) S. B. Dumanis et al.   JOURNAL OF NEUROSCIENCE

The Role of Apolipoprotein E in Alzheimer's Disease

(2009) Jungsu Kim et al.   NEURON

The Rac GTPase-activating bacterial protein toxin CNF1 induces analgesia up-regulating μ-opioid receptors

(2009) Flaminia Pavone et al.   PAIN

Revision of the apolipoprotein E compensatory mechanism recruitment hypothesis

(2008) S. Duke Han et al.   Alzheimers & Dementia

Modulation of astrocytic metabolic phenotype by proinflammatory cytokines

(2008) Mathilde Gavillet et al.   GLIA

Reassessing the amyloid cascade hypothesis of Alzheimer's disease

(2008) Sanjay W. Pimplikar   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective

(2008) Solomon S Shaftel et al.   Journal of Neuroinflammation

Regulation of hippocampal long-term potentiation by p21-activated protein kinase 1 (PAK1)

(2008) Suhail Asrar et al.   NEUROPHARMACOLOGY