Hypoxia–Induced Cytotoxic Drug Resistance in Osteosarcoma Is Independent of HIF-1Alpha

Hypoxia-Induced Decrease in p53 Protein Level and Increase in c-jun DNA Binding Activity Results in Cancer Cell Resistance to Etoposide

(2015) Jean-Philippe Cosse et al.   NEOPLASIA

The Novel Bcl-2 Inhibitor ABT-737 Is More Effective in Hypoxia and Is Able to Reverse Hypoxia-Induced Drug Resistance in Neuroblastoma Cells

(2011) T. Klymenko et al.   MOLECULAR CANCER THERAPEUTICS

HIF-1α-dependent autophagy protects HeLa cells from fenretinide (4-HPR)-induced apoptosis in hypoxia☆

(2010) Xiao-Wen Liu et al.   PHARMACOLOGICAL RESEARCH

Hypoxia-Inducible Factor 1α Determines Gastric Cancer Chemosensitivity via Modulation of p53 and NF-κB

(2010) Nadine Rohwer et al.   PLoS One

Hypoxia confers protection against apoptosis via the PI3K/Akt pathway in endothelial progenitor cells

(2009) Tao Dai et al.   ACTA PHARMACOLOGICA SINICA

Hypoxia-induced autophagy contributes to the chemoresistance of hepatocellular carcinoma cells

(2009) Jianrui Song et al.   Autophagy

Contribution of HIF-1 and drug penetrance to oxaliplatin resistance in hypoxic colorectal cancer cells

(2009) D L Roberts et al.   BRITISH JOURNAL OF CANCER

Suppression of Hypoxia-Inducible Factor 2  Restores p53 Activity via Hdm2 and Reverses Chemoresistance of Renal Carcinoma Cells

(2009) A. M. Roberts et al.   CANCER RESEARCH

Effect of HIF-1 modulation on the response of two- and three-dimensional cultures of human colon cancer cells to 5-fluorouracil

(2009) Raffaella Ravizza et al.   EUROPEAN JOURNAL OF CANCER

Hypoxia induces chemoresistance in ovarian cancer cells by activation of signal transducer and activator of transcription 3

(2009) Karuppaiyah Selvendiran et al.   INTERNATIONAL JOURNAL OF CANCER

Hypoxia induced paclitaxel resistance in human ovarian cancers via hypoxia-inducible factor 1α

(2009) Lei Huang et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Hypoxia prevents etoposide-induced DNA damage in cancer cells through a mechanism involving hypoxia-inducible factor 1

(2009) R. Sullivan et al.   MOLECULAR CANCER THERAPEUTICS

Pim-1 plays a pivotal role in hypoxia-induced chemoresistance

(2009) J Chen et al.   ONCOGENE

Effects of lentivirus-mediated HIF-1α knockdown on hypoxia-related cisplatin resistance and their dependence on p53 status in fibrosarcoma cells

(2008) J Hao et al.   CANCER GENE THERAPY

Opposite Effects of Notch-1 and Notch-2 on Mesothelioma Cell Survival under Hypoxia Are Exerted through the Akt Pathway

(2008) I. Graziani et al.   CANCER RESEARCH

Phosphatidylinositol 3-Kinase Inhibition Broadly Sensitizes Glioblastoma Cells to Death Receptor- and Drug-Induced Apoptosis

(2008) D. Opel et al.   CANCER RESEARCH

Hypoxia Markers in Human Osteosarcoma: An Exploratory Study

(2008) Hiroo Mizobuchi et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Hypoxia induces protection against etoposide-induced apoptosis: molecular profiling of changes in gene expression and transcription factor activity

(2008) Audrey Sermeus et al.   Molecular Cancer

Hypoxia-induced resistance to anticancer drugs is associated with decreased senescence and requires hypoxia-inducible factor-1 activity

(2008) R. Sullivan et al.   MOLECULAR CANCER THERAPEUTICS

Expression and significance of hypoxemia-inducible factor-1α in osteosarcoma of the jaws

(2008) Wei-liang Chen et al.   ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS