EZH2-Mediated H3K27me3 Is Involved in Epigenetic Repression of Deleted in Liver Cancer 1 in Human Cancers

Enhancer of zeste homolog 2 epigenetically silences multiple tumor suppressor microRNAs to promote liver cancer metastasis

(2012) Sandy Leung-Kuen Au et al.   HEPATOLOGY

Aberrations of EZH2 in Cancer

(2011) A. Chase et al.   CLINICAL CANCER RESEARCH

3-Deazaneplanocin A is a promising therapeutic agent for the eradication of tumor-initiating hepatocellular carcinoma cells

(2011) Tetsuhiro Chiba et al.   INTERNATIONAL JOURNAL OF CANCER

Silencing of Kruppel-like factor 2 by the histone methyltransferase EZH2 in human cancer

(2011) H Taniguchi et al.   ONCOGENE

DLC1 Negatively Regulates Angiogenesis in a Paracrine Fashion

(2010) Y.-P. Shih et al.   CANCER RESEARCH

An oncogene–tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-κB

(2010) Junxia Min et al.   NATURE MEDICINE

The neuronal repellent SLIT2 is a target for repression by EZH2 in prostate cancer

(2010) J Yu et al.   ONCOGENE

Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells

(2009) W. Fiskus et al.   BLOOD

Rho-kinase 2 is frequently overexpressed in hepatocellular carcinoma and involved in tumor invasion

(2009) Carmen Chak-Lui Wong et al.   HEPATOLOGY

DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation

(2009) T. B. Miranda et al.   MOLECULAR CANCER THERAPEUTICS

Stem cell regulation by polycomb repressors: postponing commitment

(2008) Alexandra M Pietersen et al.   CURRENT OPINION IN CELL BIOLOGY

Enhancer of Zeste Homologue 2 (EZH2) Down-regulates RUNX3 by Increasing Histone H3 Methylation

(2008) Satoshi Fujii et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Roles of the EZH2 histone methyltransferase in cancer epigenetics

(2008) Jeffrey A. Simon et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Repression of E-cadherin by the polycomb group protein EZH2 in cancer

(2008) Q Cao et al.   ONCOGENE

Cancer Genes Hypermethylated in Human Embryonic Stem Cells

(2008) Vincenzo Calvanese et al.   PLoS One

Deleted in Liver Cancer 1 (DLC1) Negatively Regulates Rho/ROCK/MLC Pathway in Hepatocellular Carcinoma

(2008) Carmen Chak-Lui Wong et al.   PLoS One

DLC-1 suppresses non-small cell lung cancer growth and invasion by RhoGAP-dependent and independent mechanisms

(2007) Kevin D. Healy et al.   MOLECULAR CARCINOGENESIS