Alternative CHRNB4 3′-UTRs Mediate the Allelic Effects of SNP rs1948 on Gene Expression

Transgenic over expression of nicotinic receptor alpha 5, alpha 3, and beta 4 subunit genes reduces ethanol intake in mice

(2012) Xavier Gallego et al.   ALCOHOL

Variants Located Upstream of CHRNB4 on Chromosome 15q25.1 Are Associated with Age at Onset of Daily Smoking and Habitual Smoking

(2012) Manav Kapoor et al.   PLoS One

Overexpression of the CHRNA5/A3/B4 genomic cluster in mice increases the sensitivity to nicotine and modifies its reinforcing effects

(2011) Xavier Gallego et al.   AMINO ACIDS

Differential genome-wide profiling of tandem 3' UTRs among human breast cancer and normal cells by high-throughput sequencing

(2011) Y. Fu et al.   GENOME RESEARCH

Rare missense variants in CHRNB4 are associated with reduced risk of nicotine dependence

(2011) Gabe Haller et al.   HUMAN MOLECULAR GENETICS

Habenular α5 nicotinic receptor subunit signalling controls nicotine intake

(2011) Christie D. Fowler et al.   NATURE

Aversion to Nicotine Is Regulated by the Balanced Activity of β4 and α5 Nicotinic Receptor Subunits in the Medial Habenula

(2011) Silke Frahm et al.   NEURON

In Vitro and Ex Vivo Analysis of CHRNA3 and CHRNA5 Haplotype Expression

(2011) Glenn A. Doyle et al.   PLoS One

Incorporating age at onset of smoking into genetic models for nicotine dependence: evidence for interaction with multiple genes

(2010) Richard A. Grucza et al.   ADDICTION BIOLOGY

CHRNB2 promoter region: association with subjective effects to nicotine and gene expression differences

(2010) N. R. Hoft et al.   GENES BRAIN AND BEHAVIOR

Rapid Communication: Nerve Growth Factor Increases the Transcriptional Activity of the Rat Neuronal Nicotinic Acetylcholine Receptor β4 Subunit Promoter in Transfected PC12 Cells

(2010) Minjie Hu et al.   JOURNAL OF NEUROCHEMISTRY

ASCL1 Regulates the Expression of the CHRNA5/A3/B4 Lung Cancer Susceptibility Locus

(2010) Ma. R. D. Improgo et al.   MOLECULAR CANCER RESEARCH

Sequence variants at CHRNB3–CHRNA6 and CYP2A6 affect smoking behavior

(2010) Thorgeir E Thorgeirsson et al.   NATURE GENETICS

Genome-wide meta-analyses identify multiple loci associated with smoking behavior

(2010)   NATURE GENETICS

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

(2010) Jason Z Liu et al.   NATURE GENETICS

Variation in Nicotinic Acetylcholine Receptor Genes is Associated with Multiple Substance Dependence Phenotypes

(2010) Richard Sherva et al.   NEUROPSYCHOPHARMACOLOGY

A transcriptional regulatory element critical for CHRNB4 promoter activity in vivo

(2010) M.D. Scofield et al.   NEUROSCIENCE

Temporally- and spatially-regulated transcriptional activity of the nicotinic acetylcholine receptor β4 subunit gene promoter

(2010) L. Bruschweiler-Li et al.   NEUROSCIENCE

Human α3β4 Neuronal Nicotinic Receptors Show Different Stoichiometry if They Are Expressed in Xenopus Oocytes or Mammalian HEK293 Cells

(2010) Paraskevi Krashia et al.   PLoS One

Variants in nicotinic acetylcholine receptors α5 and α3 increase risks to nicotine dependence

(2009) Xiangning Chen et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Structural and functional diversity of native brain neuronal nicotinic receptors

(2009) Cecilia Gotti et al.   BIOCHEMICAL PHARMACOLOGY

Genetic Variants on Chromosome 15q25 Associated with Lung Cancer Risk in Chinese Populations

(2009) C. Wu et al.   CANCER RESEARCH

The CHRNA5-CHRNA3-CHRNB4 Nicotinic Receptor Subunit Gene Cluster Affects Risk for Nicotine Dependence in African-Americans and in European-Americans

(2009) N. L. Saccone et al.   CANCER RESEARCH

Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells

(2009) Christine Mayr et al.   CELL

A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis

(2009) Gabriele Siegel et al.   NATURE CELL BIOLOGY

microRNAs at the synapse

(2009) Gerhard Schratt   NATURE REVIEWS NEUROSCIENCE

Transcription factor assembly on the nicotinic receptor β4 subunit gene promoter

(2009) Michael D. Scofield et al.   NEUROREPORT

Human neuronal acetylcholine receptor A5-A3-B4 haplotypes are associated with multiple nicotine dependence phenotypes

(2009) Timothy B. Baker et al.   NICOTINE & TOBACCO RESEARCH

The effect of alcohol and nicotine abuse on gene expression in the brain

(2009) Traute Flatscher-Bader et al.   NUTRITION RESEARCH REVIEWS

Mammalian Nicotinic Acetylcholine Receptors: From Structure to Function

(2009) Edson X. Albuquerque et al.   PHYSIOLOGICAL REVIEWS

Convergence of genetic findings for nicotine dependence and smoking related diseases with chromosome 15q24-25

(2009) Laura Jean Bierut   TRENDS IN PHARMACOLOGICAL SCIENCES

Variants in Nicotinic Receptors and Risk for Nicotine Dependence

(2008) Laura Jean Bierut et al.   AMERICAN JOURNAL OF PSYCHIATRY

The CHRNA5/A3/B4 Gene Cluster Variability as an Important Determinant of Early Alcohol and Tobacco Initiation in Young Adults

(2008) Isabel R. Schlaepfer et al.   BIOLOGICAL PSYCHIATRY

Nicotinic Receptor Gene Variants Influence Susceptibility to Heavy Smoking

(2008) V. L. Stevens et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

The CHRNA5-A3 Region on Chromosome 15q24-25.1 Is a Risk Factor Both for Nicotine Dependence and for Lung Cancer

(2008) Margaret R. Spitz et al.   JNCI-Journal of the National Cancer Institute

Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence

(2008) J C Wang et al.   MOLECULAR PSYCHIATRY

α-5/α-3 nicotinic receptor subunit alleles increase risk for heavy smoking

(2008) W Berrettini et al.   MOLECULAR PSYCHIATRY

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

(2008) Thorgeir E. Thorgeirsson et al.   NATURE

Multifunctional deadenylase complexes diversify mRNA control

(2008) Aaron C. Goldstrohm et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Chromosome 15q25.1 genetic markers associated with level of response to alcohol in humans

(2008) G. Joslyn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP

(2008) Gary A. Wayman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proliferating Cells Express mRNAs with Shortened 3' Untranslated Regions and Fewer MicroRNA Target Sites

(2008) R. Sandberg et al.   SCIENCE

A Candidate Gene Approach Identifies the CHRNA5-A3-B4 Region as a Risk Factor for Age-Dependent Nicotine Addiction

(2008) Robert B. Weiss et al.   PLoS Genetics